CD70
CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor binding and protease binding.
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, FuncS
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, FC, FuncS, IHC-Fr, IP
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, ADCC, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: FC, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
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- Type: Human antibody
- Application: FC, WB
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, Neut
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, FuncS, Neut, IP
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, Neut
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- Species Reactivity: Mouse
- Type: Rat IgG2
- Application: Block, FC, Inhib, IP
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, Neut
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Type: Human antibody
- Application: FC, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: ELISA, Inhib, ADCC, ADCP, CDC, FuncS
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: ELISA, FC, Block
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Block, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Block, FuncS
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- Type: Human antibody
- Application: FC, WB
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- Type: Human antibody
- Application: FC, WB
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- Type: Human antibody
- Application: FC, WB
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- Type: Human antibody
- Application: ELISA, FC, WB
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- Type: Human antibody
- Application: ELISA, FC, WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IF, IHC, IP
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Target: CD70
- Species Reactivity: Human
- Cytokine 1: IFNγ
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IFNγ
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA, FC
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- Target: CD70
- Linker: cleavable di-peptide linker
- Drug: Duocarmycins
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- Target: CD70
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD70
- Linker: maleimidebutaryl-VC
- Drug: Duocarmycins
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- Target: CD70
- Linker: β-glucuronide linker
- Drug: Doxorubicin
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (dimethylvaline-valine-dolaisoleuine-dolaproine-phenylalanine-p-phenylenediamine)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (dimethylvaline-valine-dolaisoleuine-dolaproine-phenylalanine-p-phenylenediamine)
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- Target: CD70
- Linker: mc-VC-PABC(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: C-labeled MMAF(C-labeled monomethylauristatin F)
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- Target: CD70
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
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- Target: CD70
- Linker: maleimidocaproyl-valine-alanine
- Drug: pyrrolobenzodiazepine (PBD) dimers
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- Target: CD27L
- Linker: Noncleavable thioether linker
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD70
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: bac-VC
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: bac
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: β-glucuronide linker
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: β-glucuronide linker
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD70
- Linker: β-glucuronide linker
- Drug: CBI Minor Groove Binder
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- Target: CD70
- Linker: β-glucuronide linker
- Drug: Camptothecin Analog
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- Target: CD70
- Linker: α-glucuronide
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: α-glucuronide
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD70
- Linker: VC-PABC (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: CC-1065 (rachelmycin)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (auristatin phenylalanine phenylenediamine)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (auristatin phenylalanine phenylenediamine)
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- Target: CD70
- Linker: VC-PABC(valine-citrulline-p-aminobenzylcarbamate)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD27L
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MGBA
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- Target: CD70
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: pyrrolobenzodiazepine (PBD) dimers
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