CD70
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Loading...- Anti-CD70 monoclonal antibody (MDX-1411) (Gly-008CL)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
- Rat Anti-CD70 Recombinant Antibody (clone 4F2-12) (HPAB-M0487-YC)
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- Species Reactivity: Canine
- Type: Rat IgG2a, κ
- Application: FC
- Anti-Human CD70 Recombinant Antibody (TAB-138CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human CD70 Recombinant Antibody (VL-8-VH) (TAB-340LC)
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- Type: Human antibody
- Application: FC, WB
- Anti-Human CD70 Recombinant Antibody (VH-8-VL) (TAB-341LC)
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- Type: Human antibody
- Application: FC, WB
- Human Anti-CD70 Recombinant Antibody (TAB-342LC) (TAB-342LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (TAB-335LC-S(P)) (TAB-335LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Anti-Human CD70 Recombinant Antibody scFv Fragment (Mb VLVH) (TAB-336LC-S(P))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody scFv Fragment (Mb VHVL) (TAB-337LC-S(P))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody scFv Fragment (VL-5-VH) (TAB-338LC-S(P))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody scFv Fragment (VH-5-VL) (TAB-339LC-S(P))
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- Type: Human antibody
- Application: FC, ELISA
- Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-335LC-F(E)) (TAB-335LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Anti-Human CD70 Recombinant Antibody Fab Fragment (Mb VLVH) (TAB-336LC-F(E))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody Fab Fragment (Mb VHVL) (TAB-337LC-F(E))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody Fab Fragment (VL-5-VH) (TAB-338LC-F(E))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody Fab Fragment (VH-5-VL) (TAB-339LC-F(E))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody Fab Fragment (VL-8-VH) (TAB-340LC-F(E))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody Fab Fragment (VH-8-VL) (TAB-341LC-F(E))
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- Type: Human antibody
- Application: FC, ELISA
- Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-342LC-F(E)) (TAB-342LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-CD70 Recombinant Antibody (HPAB-0101-LSX) (HPAB-0101-LSX)
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: ELISA, Inhib, ADCC, ADCP, CDC, FuncS
- Human Anti-CD70 Recombinant Antibody (TAB-335LC) (TAB-335LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA
- Anti-Human CD70 Recombinant Antibody (Mb VLVH) (TAB-336LC)
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- Type: Human antibody
- Application: ELISA, FC, WB
- Anti-Human CD70 Recombinant Antibody (Mb VHVL) (TAB-337LC)
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- Type: Human antibody
- Application: ELISA, FC, WB
- Anti-Human CD70 Recombinant Antibody (VL-5-VH) (TAB-338LC)
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- Type: Human antibody
- Application: FC, WB
- Anti-Human CD70 Recombinant Antibody (VH-5-VL) (TAB-339LC)
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- Type: Human antibody
- Application: FC, WB
- Human Anti-CD70 Recombinant Antibody (HPAB-0095-LSX) (HPAB-0095-LSX)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, ADCC, FuncS
- Human Anti-CD70 Recombinant Antibody (HPAB-0096-LSX) (HPAB-0096-LSX)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Block, FuncS
- Human Anti-CD70 Recombinant Antibody (HPAB-0097-LSX) (HPAB-0097-LSX)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Block, FuncS
- Human Anti-CD70 Recombinant Antibody (HPAB-0099-LSX) (HPAB-0099-LSX)
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: ELISA, FC, Block
- Human Anti-CD70 Recombinant Antibody (HPAB-0100-LSX) (HPAB-0100-LSX)
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: ELISA, Inhib, ADCC, ADCP, CDC, FuncS
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
- Human Anti-CD70 Recombinant Antibody (HPAB-0468-WJ) (HPAB-0468-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody (HPAB-0469-WJ) (HPAB-0469-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody (HPAB-0470-WJ) (HPAB-0470-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody (HPAB-0471-WJ) (HPAB-0471-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody (HPAB-0472-WJ) (HPAB-0472-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody (HPAB-0473-WJ) (HPAB-0473-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody (HPAB-0474-WJ) (HPAB-0474-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Mouse Anti-CD70 Recombinant Antibody (clone m1F6) (HPAB-AP584-YC)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: FC, ADCC, CDC, FuncS
- Human Anti-CD70 Recombinant Antibody (clone c1F6) (HPAB-AP585-YC)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) IgG
- Application: FC, ADCC, CDC, FuncS
- Human Anti-CD70 Recombinant Antibody (clone h1F6-HHLA) (HPAB-AP586-YC)
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- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Humanized (mouse/human) IgG
- Application: FC, ADCC, CDC, FuncS
- Human Anti-CD70 Recombinant Antibody (clone h1F6-HELA) (HPAB-AP587-YC)
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- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Humanized (mouse/human) IgG
- Application: FC, ADCC, CDC, FuncS
- Mouse Anti-CD70 Recombinant Antibody (clone TAN 1-7) (FAMAB-1735CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG2a
- Application: Block, ELISA, FC, IF
- Mouse Anti-CD70 Recombinant Antibody (clone TAN1-6) (FAMAB-1763CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG2a
- Application: Block, WB, FC, IF
- Mouse Anti-CD70 Antibody (clone TAN 1-7), mRNA (FAMAB-1735CQ-mRNA)
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- Species Reactivity: Mouse
- Mouse Anti-CD70 Antibody (clone TAN1-6), mRNA (FAMAB-1763CQ-mRNA)
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- Species Reactivity: Mouse
- Human Anti-CD70 Antibody (Gly-008CL-mRNA), mRNA (Gly-008CL-mRNA)
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- Human Anti-CD70 Recombinant Antibody (VS-0723-WK5) (VS-0723-WK5)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC
- Human Anti-CD70 Recombinant Antibody (TAB-343LC) (TAB-343LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Anti-Human CD70 Recombinant Antibody scFv Fragment (VL-8-VH) (TAB-340LC-S(P))
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- Type: Human antibody
- Application: FC, ELISA
- Anti-Human CD70 Recombinant Antibody scFv Fragment (VH-8-VL) (TAB-341LC-S(P))
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- Type: Human antibody
- Application: FC, ELISA
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (TAB-342LC-S(P)) (TAB-342LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (TAB-343LC-S(P)) (TAB-343LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (TAB-344LC-S(P)) (TAB-344LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
- Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-343LC-F(E)) (TAB-343LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-344LC-F(E)) (TAB-344LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IF, IHC, IP
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
- Anti-CD70 Antibody-Cytokine Fusion Protein, IgG-IFNγ (ACFP-SH160)
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- Target: CD70
- Species Reactivity: Human
- Cytokine 1: IFNγ
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IFNγ
- Rat Anti-CD70 Recombinant Antibody (clone 4F2-12); Fab Fragment (HPAB-M0487-YC-F(E))
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- Species Reactivity: Canine
- Type: Rat Fab
- Application: FC
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0471-WJ-S(P)) (HPAB-0471-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0472-WJ-S(P)) (HPAB-0472-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0468-WJ-F(E)) (HPAB-0468-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0469-WJ-F(E)) (HPAB-0469-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0468-WJ-S(P)) (HPAB-0468-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0469-WJ-S(P)) (HPAB-0469-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0470-WJ-S(P)) (HPAB-0470-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Anti-CD70 (clone 2F2)-vc-AFP ADC (ADC-115CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (dimethylvaline-valine-dolaisoleuine-dolaproine-phenylalanine-p-phenylenediamine)
- Anti-CD70 (clone 2F2)-vc-MMAF ADC (ADC-116CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (h1F6)-vc-AFP ADC (ADC-071LCT)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (auristatin phenylalanine phenylenediamine)
- Anti-CD70 (c1F6)-vc-AFP ADC (ADC-072LCT)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (auristatin phenylalanine phenylenediamine)
- Anti-CD70 (clone h1F6 )-mc-vc-PABC-MMAE ADC (ADC-155LZY)
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- Target: CD70
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
- Anti-CD70 Immunohistochemistry Kit (VS-0525-XY1215)
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- Species Reactivity: Human
- Target: CD70
- Application: IHC
- Anti-CD70 (h1F6)-vc-rachelmycin ADC (ADC-073LCT)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: CC-1065 (rachelmycin)
- Anti-CD70 (h1F6)-vc-MMAF ADC (ADC-074LCT)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (1F6)-val-cit-PABC-MMAF ADC (ADC-075LCT)
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- Target: CD70
- Linker: VC-PABC (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD70 (h1F6)-α-glucuronide-MMAE ADC (ADC-076LCT)
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- Target: CD70
- Linker: α-glucuronide
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD70 (h1F6)-α-glucuronide-MMAF ADC (ADC-077LCT)
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- Target: CD70
- Linker: α-glucuronide
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (clone 1F6)-vc-MMAE ADC (ADC-111CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD70 (clone 1F6)-vc-AFP ADC (ADC-112CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (dimethylvaline-valine-dolaisoleuine-dolaproine-phenylalanine-p-phenylenediamine)
- Anti-CD70 (clone 1F6)-vc-MMAF ADC (ADC-113CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (clone 2F2)-vc-MMAE ADC (ADC-114CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD70 (1F6)-C4v2-bac-MMAF ADC (ADC-066LCT)
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- Target: CD70
- Linker: bac
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (1F6)-C4v2-bac-vc-MMAF ADC (ADC-067LCT)
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- Target: CD70
- Linker: bac-VC
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (1F6)-C4v2-mc-MMAF ADC (ADC-068LCT)
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- Target: CD70
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (1F6)-C4v2-mc-vc-MMAF ADC (ADC-069LCT)
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- Target: CD70
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70(h1F6)-mc-vc-PBD ADC (ADC-176LCT)
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- Target: CD70
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: pyrrolobenzodiazepine (PBD) dimers
- Anti-CD70-vc-MGBA ADC (ADC-014LZY)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MGBA
- Anti-CD70 (clone h1F6)-mc-MMAF ADC (ADC-036LZY)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-CD27L-MCC-DM1 ADC (ADC-038LZY)
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- Target: CD27L
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD70 (clone h1F6)-vc-PABC-MMAF ADC (ADC-051LZY)
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- Target: CD70
- Linker: VC-PABC(valine-citrulline-p-aminobenzylcarbamate)
- Drug: MMAF (monomethyl auristatin F)
- Anti-CD70 (clone h1F6)-MCC-DM1 ADC (ADC-052LZY)
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- Target: CD70
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD27L-DM1 ADC (ADC-127LZY)
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- Target: CD27L
- Linker: Noncleavable thioether linker
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD70 (clone h1F6239C)-PBD ADC (ADC-135LZY)
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- Target: CD70
- Linker: maleimidocaproyl-valine-alanine
- Drug: pyrrolobenzodiazepine (PBD) dimers
- Anti-CD70 (clone h1F6 C4v2)-mc-C-labeled MMAF ADC (ADC-215LZY)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: C-labeled MMAF(C-labeled monomethylauristatin F)
- Anti-CD70 (clone 1F6)-mc-vc-PABC-MMAF ADC (ADC-222LZY)
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- Target: CD70
- Linker: mc-VC-PABC(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-CD70 (clone 1F6)-mc-MMAF ADC (ADC-223LZY)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD70
- Linker: cleavable di-peptide linker
- Drug: Duocarmycins
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

