Anti-Human CD70 Recombinant Antibody (Vorsetuzumab Mafodotin) (CAT#: TAB-882)

Recombinant human monoclonal antibody expressed in CHO binding to human CD70. Vorsetuzumab mafodotin is an antibody-drug conjugate (ADC) directed to the protein CD70 designed for the treatment of cancer. It is a humanized monoclonal antibody, vorsetuzumab, conjugated with noncleavable monomethyl auristatin F (MMAF), a cytotoxic agent.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Humanized (from mouse)
  • Type
  • IgG1 - kappa
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
  • CAS
  • 1165741-01-4
  • Generic Name
  • Vorsetuzumab mafodotin
  • MW
  • 150 kDa
  • Related Disease
  • Non-Hodgkin's lymphoma (NHL)

Product Property

  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

Target

  • Alternative Names
  • Vorsetuzumab mafodotin;1165741-01-4;SGN-75;h1F6-mcMMAF(4);SGN-75;CD70;CD70 molecule;CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7;CD70 antigen;CD27L;CD27-L;CD27 ligand;Ki-24 antigen;surface antigen CD70;tumor necrosis factor ligand

Related Resources

  • Biosimilar Overview
Please refer to Vorsetuzumab Mafodotin Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Vorsetuzumab Mafodotin.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CD70"

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-404CQ Rat Anti-Cd70 Recombinant Antibody (clone MAB0825) Block, FC, Inhib, IP Rat IgG2

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H76 Afuco™ Anti-CD70 ADCC Recombinant Antibody (Vorsetuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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