Recombinant Anti-CD70 Vesicular Antibody, EV Displayed (VS-0425-YC77) (CAT#: VS-0425-YC77)
The Recombinant Anti-CD70 Vesicular Antibody, EV Displayed (VS-0425-YC77) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD70-expressed cells or tissues. The CD70 is a protein involved in immune system signaling pathways, associated with conditions like Acute Myocarditis.
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Subcellular Location and Protein Expression
RNA Expression

Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg

Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg

Figure 3 RNA cell line category: Cell line enhanced (SiHa, THP-1, U-251 MG, U-266/70, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD70
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD70 molecule
- Cellular Localization
- Nucleoplasm
- Introduction
- CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor binding and protease binding.
- Alternative Names
- CD27L, CD27LG, TNFSF7
- Gene ID
- 970
- UniProt ID
- P32970
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1584z | Mouse Anti-CD70 Recombinant Antibody (clone 24B8) | FC, IF, IHC, IP | Mouse IgG1, κ |
HPAB-0468-WJ | Human Anti-CD70 Recombinant Antibody (HPAB-0468-WJ) | ELISA | Human IgG |
HPAB-0469-WJ | Human Anti-CD70 Recombinant Antibody (HPAB-0469-WJ) | ELISA | Human IgG |
VS1-YJ31 | Mouse Anti-CD70 Recombinant Antibody (clone BU69), FITC | IHC-Fr, FC | Mouse IgG1 |
VS-0723-WK186 | Rabbit Anti-CD70 Recombinant Antibody (VS-0723-WK186) | ELISA, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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