Antibody ESC14 is a fully human, mouse/human cross-reactive, high affinity anti-FAP antibody that induces relevant regulatory activities on target cells pointing out to their therapeutic impact.
Figure 1 Human Anti-FAP Recombinant Antibody (HPAB-0175-CN) in SDS-PAGE
SDS-PAGE analysis of HPAB-0175-CN in β-mercaptoethanol-reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively. And non-reduced protein migrates as about 135-245 kDa.
Figure 2 Human Anti-FAP Recombinant Antibody (HPAB-0175-CN) in SEC-HPLC
The purity of HPAB-0175-CN was greater than 95% as determined by SEC-HPLC.
Column: 3 µm, 7.8 x 300 nm
Mobile phase: 150 mM Sodium Phosphate Buffer, pH 7.0
Detection: UV 280 nm
Injection: 10 µl
Figure 3 Human Anti-FAP Recombinant Antibody (HPAB-0175-CN) in DB
Dot blot analysis of HPAB-0175-CN was performed by loading human FAP protein active dimer (His Tag).
HPAB-0175-CN incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Figure 4 Human Anti-FAP Recombinant Antibody (HPAB-0175-CN) in WB
Western blot analysis of HPAB-0175-CN was performed by loading human FAP protein active dimer (His Tag).
HPAB-0175-CN incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (0.1 μg)
Lane 2: Reducing antigen (0.3 μg)
Lane 3: Reducing antigen (0.6 μg)
Figure 5 Human Anti-FAP Recombinant Antibody (HPAB-0175-CN) in ELISA
ELISA analysis of HPAB-0175-CN was performed by coating with human FAP protein active dimer (His Tag).
The secondary antibody: HRP-Anti-Human IgG (H+L)
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2277z | Mouse Anti-FAP Recombinant Antibody (clone 36B12) | FC, IF, IP | Mouse IgG1 |
HPAB-0668-YJ | Human Anti-FAP Recombinant Antibody (HPAB-0668-YJ) | ELISA, Inhib, IHC, IF, FuncS | Human IgG1 |
HPAB-A1368-YJ | Mouse Anti-FAP Recombinant Antibody (clone F19) | ELISA, FuncS, RIA, IP, IF, IHC, IA, Block | Mouse IgG |
HPAB-A1373-YJ | Human Anti-FAP Recombinant Antibody (clone 34) | ELISA, IHC, FC, Inhib | Human IgG1 |
HPAB-A1374-YJ | Human Anti-FAP Recombinant Antibody (clone 18) | ELISA, FC, Inhib | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-211 | Anti-Human FAP Recombinant Antibody (Sibrotuzumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-022WM | Human Anti-FAP Recombinant Antibody (TAB-022WM) | FC, ELISA | Human IgG1 |
TAB-024WM | Human Anti-FAP Recombinant Antibody (TAB-024WM) | IHC, ELISA, FC, IF | Human IgG1 |
TAB-022WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) | FC, ELISA | Human scFv |
TAB-022WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) | FC, ELISA | Human Fab |
TAB-024WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-024WM-F(E)) | ELISA, FC, IF | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-150LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-151LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-152LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-153LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-150LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-151LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-152LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-153LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0170-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) | ELISA, IF | Human scFv |
HPAB-0171-CN-S(P) | Mouse Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0171-CN-S(P)) | ELISA | Mouse scFv |
HPAB-0173-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0173-CN-S(P)) | ELISA | Humanized scFv |
HPAB-0176-CN-S(P) | Mouse Anti-FAP Recombinant Antibody (clone cF19); scFv Fragment | ELISA, FC, IHC, IP, IF | Mouse scFv |
HPAB-2062-FY-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2062-FY-S(P)) | FC, ELISA, IF | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0170-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) | ELISA, IF | Human Fab |
HPAB-0171-CN-F(E) | Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) | ELISA | Mouse Fab |
HPAB-0173-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) | ELISA | Humanized Fab |
HPAB-0175-CN-F(E) | Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment | ELISA, WB, FC, IHC, IP | Human Fab |
HPAB-2061-FY-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-2061-FY-F(E)) | FC, ELISA, IF | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0619-CN | Recombinant Dromedary Anti-FAP Single Domain Antibody (Nb67) | ELISA | VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-211 | Afuco™ Anti-FAP ADCC Recombinant Antibody (Sibrotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0661 | PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-CN0662 | APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-CN0663 | FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-CN0664 | H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-YF573 | H-2Kb/Human muFAP alpha (SDYYFSWL) MHC Pentamer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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