Anti-human IL6 Recombinant Antibody (MH166) (TAB-679LC) (CAT#: TAB-679LC)
Recombinant monoclonal antibody MH166 is a mouse monoclonal antibody that specifically binds to human IL-6. MH166 was produced in mice immunized with the recombinant IL-6 protein. It can be potentially used in the treatment studies of inflammatory disease.
Specific Inquiry
Inhib
Figure 1 MH166 inhibits in vitro activity of hIL-6.
NZB/W F1 B cells were cultured with 20 U/ml of natural hIL-6 in the presence or absence of MH 166. After 5 days of culturing, the IgM in the culture supematants was measured by ELISA. The control level was 272.1 ng/ml and the spontaneous level (without lL-6) was 180.4 ng/ml.
Mihara, M., Koishihara, Y., Fukui, H., Yasukawa, K., & Ohsugi, Y. (1991). Murine anti-human IL-6 monoclonal antibody prolongs the half-life in circulating blood and thus prolongs the bioactivity of human IL-6 in mice. Immunology, 74(1), 55.
FuncS
Figure 2 Effect of antibodies on the growth of S6B45 cells in vitro.
S6B45 cells were recovered from the tumor-bearing mice and cultured with indicated concentrations of control mouse antibody (●), anti-human IL-6R mAb PM1 (○), anti-human IL-6 mAb MH166 (▲) or anti-human gp130 mAb AM64 (×). The average of the duplicate is shown.
Suzuki, H., Yasukawa, K., Saito, T., Goitsuka, R., Hasegawa, A., Ohsugi, Y.,... & Kishimoto, T. (1992). Anti‐human interleukin‐6 receptor antibody inhibits human myeloma growth in vivo. European journal of immunology, 22(8), 1989-1993.
Specifications
- Immunogen
- Recombinant IL-6
- Host Species
- Mouse
- Specificity
- Human
- Clone
- MH166
- Applications
- ELISA, Inhib, FuncS
- Related Disease
- Inflammatory disease
Applications
- Application Notes
- This antibody has been tested for use in Inhibition and Functional Assay.
Target
- Alternative Names
- IL6; interleukin 6; HGF; HSF; BSF2; IL-6; IFNB2; interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor
- Gene ID
- 3569
- UniProt ID
- B4DVM1
Related Resources
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Graft-versus-Host Disease
AGE-RAGE Signaling Pathway in Diabetic Complications
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone MH166"
See other products for "IL6"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-097 | Anti-Human IL6 Recombinant Antibody (Sirukumab) | FC, IP, ELISA, Neut, FuncS, IF, WB | IgG1 - kappa |
| TAB-680LC | Human Anti-IL6 Recombinant Antibody (TAB-680LC) | ELISA, FuncS | Human IgG1 |
| TAB-681LC | Human Anti-IL6 Recombinant Antibody (TAB-681LC) | ELISA, FuncS | Human IgG1 |
| TAB-682LC | Human Anti-IL6 Recombinant Antibody (TAB-682LC) | ELISA, FuncS | Human IgG1 |
| TAB-671LC-F(E) | Anti-human IL6 Fab Fragment (SK2a) | ELISA | Human antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-244 | Human Anti-IL6 Recombinant Antibody (clone YC136); Fab Fragment | WB, Block, FuncS | Human Fab |
| HPAB-0674-CN-F(E) | Human Anti-IL6 Recombinant Antibody (clone 9C8-N68T-T83S); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0030LY-F(E) | Humanized Anti-IL6 Recombinant Antibody; Fab Fragment (HPAB-0030LY-F(E)) | WB | Fab |
| HPAB-0164-YJ-F(E) | Mouse Anti-IL6 Recombinant Antibody (clone 6yl-9); Fab Fragment | ELISA, WB, Inhib, Neut | Mouse Fab |
| HPAB-1250-FY-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-1250-FY-S(P)) | ELISA | Mouse scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0026CL | Human Anti-IL6 Recombinant Antibody (TAB-0026CL) | Elisa, In vivo, FuncS, Block | Chimeric (mouse/human) IgG |
| TAB-0026CL-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0026CL-S(P)) | Elisa, In vivo, FuncS, Block | Mouse scFv |
| TAB-670LC | Anti-human IL6 Recombinant Antibody (NTS) (TAB-670LC) | ELISA, Inhib | Chimeric antibody (mouse/human) |
| TAB-670LC-F(E) | Anti-human IL6 Fab Fragment (NTS) | ELISA | Chimeric antibody (mouse/human) |
| VS3-WK1519 | Human Anti-IL6 Recombinant Antibody (clone CLLB8) | ELISA, FC | Chimeric (mouse/human) IgG1 |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0172CL-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0172CL-S(P)) | ELISA, Block, In vivo | Human scFv |
| TAB-0173CL-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0173CL-S(P)) | ELISA, Block, In vivo | Human scFv |
| TAB-0172CL-F(E) | Human Anti-IL6 Recombinant Antibody; Fab Fragment (TAB-0172CL-F(E)) | ELISA, Block, In vivo | Humanized Fab |
| TAB-678LC-S(P) | Anti-human IL6 scFv Fragment (BA399) | ELISA, FC | Humanized antibody |
| TAB-678LC-F(E) | Anti-human IL6 Fab Fragment (BA399) | ELISA, FC | Humanized antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-673LC | Anti-human IL6 Recombinant Antibody | ELISA, FC | |
| TAB-673LC-S(P) | Anti-human IL6 scFv Fragment | ELISA, FC | |
| TAB-679LC-S(P) | Anti-human IL6 scFv Fragment (MH166) | ELISA | |
| TAB-673LC-F(E) | Anti-human IL6 Fab Fragment | ELISA, FC | |
| TAB-679LC-F(E) | Anti-human IL6 Fab Fragment (MH166) | ELISA |
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-037LC | Recombinant Anti-Human IL6 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-197LC | Recombinant Anti-Human IL6 Antibody (Non-glycosylated) | ELISA | Humanized antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0284MZ | Chicken Anti-Interleukin-6 Polyclonal IgY | WB, Indirect ELISA | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1450CQ | Mouse Anti-IL6 Recombinant Antibody (clone CBL596) | Neut | Mouse IgG2a |
| NEUT-1472CQ | Mouse Anti-IL6 Recombinant Antibody (clone AS16) | IHC, IP, Neut | Mouse IgG1 |
| NEUT-1473CQ | Rat Anti-Il6 Recombinant Antibody (clone 20F3) | Block, ELISA, IHC-P, IP, Neut, WB | Rat IgG1 |
| NEUT-1475CQ | Rat Anti-Il6 Recombinant Antibody (clone 10F9) | Neut | Rat IgG2a |
| NEUT-1476CQ | Rat Anti-Il6 Recombinant Antibody (clone CBL112) | Neut, WB | Rat IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1474CQ | Rat Anti-Il6 Recombinant Antibody (clone 32C11) | Block, ELISA, WB | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1814 | Rabbit Anti-IL6 Recombinant Antibody (clone DS1814AB) | WB | Rabbit IgG |
| MOR-4277 | Rabbit Anti-IL6 Recombinant Antibody (clone SI360DS) | ELISA | Rabbit IgG |
| MOR-4622 | Rabbit Anti-IL6 Recombinant Antibody (clone TH135DS) | WB, ELISA | Rabbit IgG |
| MOR-4623 | Rabbit Anti-IL6 Recombinant Antibody (clone TH136DS) | WB | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3429 | PE-B8/Human IL6 (ILKQKIALD) MHC Tetramer | FCM | |
| MHC-LC3430 | APC-B8/Human IL6 (ILKQKIALD) MHC Tetramer | FCM |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-043CN | Human Anti-IL6 Recombinant Antibody (NS-043CN) | ELISA, WB | Human IgG1 |
| NS-043CN-F(E) | Human Anti-IL6 Recombinant Antibody; Fab Fragment (NS-043CN-F(E)) | ELISA, WB | Human Fab |
| NS-043CN-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (NS-043CN-S(P)) | ELISA, WB | Human scFv |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0030LY-S(P) | Humanized Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-0030LY-S(P)) | WB | scFv |
| HPAB-1758-FY-F(E) | Rat Anti-IL6 Recombinant Antibody; Fab Fragment (HPAB-1758-FY-F(E)) | ELISA | Rat Fab |
| HPAB-S0076-YC-S(P) | Rabbit Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-S0076-YC-S(P)) | ELISA, WB, Block, FuncS | Rabbit scFv |
| HPAB-S0077-YC-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-S0077-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-S0083-YC-S(P) | Rabbit Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-S0083-YC-S(P)) | ELISA, Block | Rabbit scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0833-CN | Mouse Anti-IL6 Recombinant Antibody (clone 1-6) | WB, IHC, IF | Mouse IgG2b |
| MRO-0834-CN | Mouse Anti-IL6 Recombinant Antibody (clone 11-D4) | WB, IHC, IF, ELISA | Mouse IgG1 |
| MRO-0835-CN | Mouse Anti-IL6 Recombinant Antibody (clone 7-A7) | WB, IHC | Mouse IgG1 |
| MRO-1969-CN | Rabbit Anti-IL6 Polyclonal Antibody (MRO-1969-CN) | WB, ELISA | Rabbit IgG |
| MRO-1970-CN | Rabbit Anti-IL6 Polyclonal Antibody (MRO-1970-CN) | WB, IF, IHC, FC | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-239 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Elsilimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-097 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Sirukumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-H26 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Enlimomab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-253 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Olokizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0166-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 6D5) | ELISA | Camelid VHH |
| HPAB-S0167-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 8F2) | ELISA | Camelid VHH |
| HPAB-S0168-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 6B12) | ELISA, Inhib | Camelid VHH |
| HPAB-S0169-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 7G4) | ELISA, Inhib | Camelid VHH |
| HPAB-S0170-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 7G5) | ELISA, Inhib | Camelid VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-679LC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.