Anti-Human MUC1 Recombinant Antibody (BOS7D10) (CAT#: TAB-427MZ)
This antibody can inhibit the proliferation and growth of tumor cells as well as induce cell death in cancer cells inducing epithelial, colon, lung, breast and ovarian tumor cells or other cells that express MUC1 proteins. The antibody BOS7D10 shows a potent inhibitory effect on cell growth as well as a potent cell death activity on MCF7 cells.
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FuncS
Figure 1 shows that the effect of BOS7D10 on cell growth is dependent on serum concentration.
H/Y2 cells were exposed to medium supplemented with 0.1% (lanes 6; 12); 0.2% (lanes 5; 11); 0.3% (lanes 4; 10); 1% (lanes 3; 9); 3% (lanes 2; 8); and 10% (lanes 1; 7) FCS. The effect of the different mAb on the H/Y2 cells was analyzed by MTT in order to measure the inhibitory effect of mAbs on cell proliferation.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- BOS7D10
- Applications
- FuncS
- Related Disease
- Epithelial, colon, lung, breast and ovarian tumor
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
- Alternative Names
- MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant;
- Gene ID
- 4582
- UniProt ID
- P15941
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2049-VHH | Recombinant Anti-human MUC1 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| HPAB-AP504-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP504-YC) | FC | Camel VHH |
| HPAB-AP505-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP505-YC) | ELISA | Camel VHH |
| HPAB-0736-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0736-YJ-VHH) | ELISA | Camelid VHH |
| HPAB-0737-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0737-YJ-VHH) | ELISA | Camelid VHH |
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