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MUC1

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Full Name :
MUC1
Keywords :
EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC

Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
IF, IP, Neut, FuncS, ELISA, FC, ICC
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
ELISA, FC, IP, FuncS, IF, Neut, IHC
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, FuncS, IF, Neut, ELISA, FC, IP
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG1
Application:
WB, ELISA, FC, IP, FuncS, IF, Neut
Species Reactivity:
Human
Application:
Cytotoxicity assay, Functional assay
Targets:
MUC1 & CD3
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
CD28 & MUC1
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
MUC1 & CD3
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
MUC1 & CD2
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
MUC1 & CD28
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Target:
CA6, a specific glycol-epitope of MUC-1
Linker:
SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
Drug:
DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
CanAg
Linker:
SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
Drug:
DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
CanAg
Linker:
SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
Drug:
DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Target:
CanAg
Linker:
SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
Drug:
DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
Mucin1
Drug:
DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
MUC1
Linker:
CL2A
Drug:
SN-38(7-ethyl-10-hydroxy camptothecin)
Target:
CanAg
Linker:
SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
Drug:
DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Target:
CanAg
Linker:
SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
Drug:
DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Target:
CanAg
Linker:
SPDB(N-succinimidyl 4-(2-pyridyldithio)butyrate)
Drug:
DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
CanAg
Linker:
SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
Drug:
[3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Target:
CanAg
Linker:
SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
Drug:
[3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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