Human Anti-PDCD1 Recombinant Antibody (clone 6F5H2L2) (CAT#: HPAB-0191-YC)
Transmembrane receptor PD-1 (programmed cell death 1, a programmed cell death) is one of gene family members CD28 in activated T cells, B cells and myeloid cells are expressed. PD-1 ligand PDL-1 and PDL-2 belong to the B7 superfamily, wherein the PDL-1 expression in a variety of cells has, including T cells, B cells and endothelial cells and epithelial cells, PDL-2 only expressed in antigen presenting cells such as dendritic cells and macrophages.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg
(Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
Specifications
- Immunogen
- Recombinant PD-1ECD-TEV-mFc
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human PDCD1
- Species Reactivity
- Human
- Clone
- 6F5H2L2
- Applications
- ELISA, FuncS
- Related Disease
- Tumor
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-900 | Anti-Human PD-1/PDCD1/CD279 Recombinant Antibody (TAB-900) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
| TAB-H55 | Human Anti-PDCD1 Recombinant Antibody (TAB-H55) | Inhib, Agonist | IgG4, κ |
| TAB-0966CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0966CL-S(P)) | ELISA | Human scFv |
| TAB-0975CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0975CL-S(P)) | ELISA | Human scFv |
| TAB-012ML | Anti-Human PDCD1 Recombinant Antibody (TAB-012ML) | ELISA, IHC, FC, IP, IF, BL | IgG4, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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