Anti-Human CD37 Recombinant Antibody (Lilotomab)
CAT#: TAB-467CQ
Recombinant monoclonal antibody to CD37. Lilotomab is a mouse monoclonal antibody that can be potentially used in the treatment of Non-Hodgkin's lymphoma (NHL).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/1848_F10_26_cr5abb8def07051_selected.jpg
Normal Tissue
Figure 2 Tonsil
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_A_5_8_val_selected.jpg
Normal Tissue
Figure 3 Colon
Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_9_3.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_7_8.jpg
Normal Tissue
Figure 5 Spleen
Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_B_8_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Daudi, HMC-1, RPMI-8226, THP-1, U-698, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104894-CD37
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG1, κ
- Specificity
- Human CD37
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Trade name
- Betalutin
- CAS
- 1453362-55-4
- Generic Name
- Lilotomab
- UNII
- 58I6YNR7BV
- Related Disease
- Non-Hodgkin's lymphoma (NHL)
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The CD37 antibody has been reported in applications of Cyt, FC, ADCC, IF.
Target
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(Creative Biolabs Cat# TAB-467CQ, RRID: AB_3111956)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Lilotomab"
Afuco™ Anti-CD37 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-467CQ)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD37. It is a mouse monoclonal antibody that can be potentially used in the treatment of Non-Hodgkin's lymphoma (NHL).
DrugMonitor™ Anti-Lilotomab Antibody (VS-1224-YC669)Lilotomab (formerly tetulomab, HH1) is a murine monoclonal antibody targeting CD37, under investigation for relapsed non-Hodgkin lymphoma treatment. The DrugMonitor™ Anti-Lilotomab Antibody (VS-1224-YC669) is an anti-drug antibody (ADA) against Lilotomab. This drug-based antibody is raised in mice immunized with the Lilotomab. The anti-Lilotomab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Lilotomab in samples.
See other products for "CD37"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1367z | Mouse Anti-CD37 Recombinant Antibody (clone 41C4) | WB, IP, IF, IHC, ELISA | Mouse IgG2b, κ |
| HPAB-AP033-YC | Human Anti-CD37 Recombinant Antibody (clone A2) | FuncS | Human IgG |
| HPAB-AP034-YC | Human Anti-CD37 Recombinant Antibody (clone B2) | FuncS | Human IgG |
| FAMAB-1051CQ | Human Anti-CD37 Recombinant Antibody (clone G28-1) | Depletion | Human IgG1 |
| FAMAB-1052CQ | Mouse Anti-CD37 Recombinant Antibody (clone WR17) | FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-904 | Anti-Human CD37 Recombinant Antibody (Otlertuzumab) | ELISA, IP, FC, FuncS, Neut, IF, ICC | VH - V-kappa - CH2 - CH3 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0272CL | Human Anti-CD37 Recombinant Antibody (TAB-0272CL) | ELISA, WB | Chimeric (mouse/human) |
| TAB-0272CL-S(P) | Human Anti-CD37 Recombinant Antibody scFv Fragment (TAB-0272CL-S(P)) | ELISA, WB | Chimeric (mouse/human) |
| TAB-0273CL-S(P) | Human Anti-CD37 Recombinant Antibody scFv Fragment (TAB-0273CL-S(P)) | Block | Chimeric (mouse/human) |
| TAB-0272CL-F(E) | Human Anti-CD37 Recombinant Antibody Fab Fragment (TAB-0272CL-F(E)) | ELISA, WB | Chimeric (mouse/human) |
| TAB-0273CL-F(E) | Human Anti-CD37 Recombinant Antibody Fab Fragment (TAB-0273CL-F(E)) | Block | Chimeric (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0159-FY-S(P) | Mouse Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-0159-FY-S(P)) | Activ, Depletion, FuncS, Inhib | Mouse scFv |
| HPAB-0163-FY-S(P) | Mouse Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-0163-FY-S(P)) | FC, Inhib | Mouse scFv |
| HPAB-AP033-YC-S(P) | Human Anti-CD37 Recombinant Antibody (clone A2); scFv Fragment | FuncS | Human scFv |
| HPAB-AP034-YC-S(P) | Human Anti-CD37 Recombinant Antibody (clone B2); scFv Fragment | FuncS | Human scFv |
| HPAB-0901-WJ-S(P) | Mouse Anti-CD37 Recombinant Antibody scFv Fragment (HPAB-0901-WJ-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-467CQ | Afuco™ Anti-CD37 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-467CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP033-YC-F(E) | Human Anti-CD37 Recombinant Antibody (clone A2); Fab Fragment | FuncS | Human Fab |
| HPAB-AP034-YC-F(E) | Human Anti-CD37 Recombinant Antibody (clone B2); Fab Fragment | FuncS | Human Fab |
| HPAB-1045-FY-S(P) | Human Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-1045-FY-S(P)) | FC, ELISA | Human scFv |
| HPAB-1046-FY-S(P) | Human Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-1046-FY-S(P)) | FC, ELISA | Human scFv |
| HPAB-1047-FY-S(P) | Human Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-1047-FY-S(P)) | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC112 | Mouse Anti-CD37 Recombinant Antibody Hexamer (VS-0924-YC112), CDC Enhanced | FC, Inhib, CDC | Antibody hexamer |
| VS-0924-YC113 | Human Anti-CD37 Recombinant Antibody Hexamer (VS-0924-YC113), CDC Enhanced | CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY21 | Human Anti-CD37 (clone chHH1.1) scFv-Fc Chimera | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY43 | CytoStream™ Mouse Anti-CD37 Recombinant Antibody (VS-0225-XY43) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC73 | Recombinant Anti-CD37 Vesicular Antibody, EV Displayed (VS-0425-YC73) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC9 | Recombinant Anti-CD37 Biparatopic Antibody, Asymmetric hetero Fab | ELISA | Asymmetric hetero Fab |
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