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    Rabbit Anti-BAX Recombinant Antibody (clone R07-4G1) (CAT#: VS3-XY3274)

    The antibody is a recombinant rabbit antibody binding with BAX (BCL2 associated X, apoptosis regulator), which plays a role in the mitochondrial apoptotic process. It recognizes and binds to human BAX. It also has cross-reactivity against mouse or rat BAX. It has been detected using Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation and Flow cytometry.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Low cell line specificity
    Figure 7 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX

    Specifications

    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse, Rat and Hamster BAX
    • Species Reactivity
    • Human, Mouse, Rat, Hamster
    • Clone
    • R07-4G1
    • Applications
    • WB, IHC-P, IP, FC
    • Related Disease
    • Colorectal Cancer; T-Cell Acute Lymphoblastic Leukemia

    Product Property

    • Clonality
    • Monoclonal
    • Aggregation
    • < 5%
    • Format
    • Liquid
    • Buffer
    • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
    • Preservative
    • 0.02% sodium azide
    • Storage
    • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • WB: 1/500-1/1000
      IHC: 1/50-1/100
      IP: 1/20
      FC: 1/50-1/100

    Target

    • Alternative Names
    • BCL2L4
    • Long Name
    • BCL2 associated X, apoptosis regulator
    • Cellular Localization
    • Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus
    • Post Translation Modifications
    • Ubiquitinated on Lys-128 and Lys-190. 'Lys-63'-linked polyubiquitin chains on Lys-128 are removed by USP12.
    • Function
    • Plays a role in the mitochondrial apoptotic process. Promotes activation of CASP3, and thereby apoptosis.

    Recommended Products

    Isotype Control

    Recommended Dilution Buffer

    Secondary Antibody

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "BAX"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Intrabody Products Single Domain Antibody Products IgG Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Antibody Magnetic Beads Non-Human Primate (NHP) Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    IAB-B001(A) Recombinant Anti-human BaX Intrabody [(D-Arg)9] ELISA, ICC, FuncS vhh-(D-Arg)9
    IAB-B001(G) Recombinant Anti-human BaX Intrabody [+36GFP] PCA, Neut, FuncS vhh-(+36GFP)
    IAB-B001(T) Recombinant Anti-human BaX Intrabody [Tat] WB, Neut, FuncS vhh-Tat

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