Rat Anti-CD86 Recombinant Antibody (clone PO3) (CAT#: VS11-QX48)
This product is a recombinant rat antibody that recognizes CD86. This antibody can be used for the following applications: FC, WB, IHC, Block, FuncS. CD86 acts as a counter-receptor for the T cell surface markers CD28 and CD152 (CTLA-4). This interaction is crucial for facilitating communication between T and B cells, providing costimulation to T cells, promoting the production of autoantibodies, and supporting Th2-mediated Ig production.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line HDLM-2 shows localization to plasma membrane & centriolar satellites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26802/1962_A12_6_selected.jpg

(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_B_8_5.jpg

(Macrophages Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_1_4.jpg

(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_8_3.jpg

(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_9_8.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000114013-CD86
Specifications
- Immunogen
- A mouse B cell line, BCL1 and fusing immune splenocytes with P3U1 myeloma cells.
- Host Species
- Rat
- Derivation
- Rat
- Type
- Rat IgG2b, κ
- Specificity
- Mouse CD86
- Species Reactivity
- Mouse
- Clone
- PO3
- Applications
- FC, WB, IHC, Block, FuncS
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2
- Gene ID
- 12524
- UniProt ID
- P42082
- Long Name
- T-lymphocyte activation antigen CD86
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD86"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L002G | anti-CD86 immunotoxin 1G10 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L002S | anti-CD86 immunotoxin 1G10 (IgG)-Sap | Cytotoxicity assay, Functional assay | |
AGTO-L002O | anti-CD86 immunotoxin 1G10 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
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