Human Anti-PRNP Recombinant Antibody (clone ch31C6)
CAT#: FAMAB-0272CQ
Recombinant Human Antibody clone ch31C6, which is specific to PRNP. The mAb 31C6 (group II) reacted with peptides from 58 to 61, which share in common residues 143-149, DWEDRYY. mAb 31C6 only reacted with MoPrPSc.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg
Normal Tissue
Figure 4 Caudate
Neuronal cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG1
- Specificity
- Mouse Prion Protein
- Species Reactivity
- Mouse
- Clone
- ch31C6
- Applications
- ELISA, WB, IHC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone ch31C6"
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1227z | Mouse Anti-PRNP Recombinant Antibody (clone 25G7) | WB, IP, IF, IHC, FC, ELISA | Mouse IgG1, κ |
| FAMAB-0050-CN | Chicken Anti-PRNP Recombinant Antibody (clone phAb4-31) | ELISA | Chicken IgG |
| FAMAB-0051-CN | Human Anti-PRNP Recombinant Antibody (clone hu4.00) | ELISA | Humanized IgG |
| FAMAB-0052-CN | Human Anti-PRNP Recombinant Antibody (clone ch4.31) | ELISA | Chimeric (chicken/human) IgG |
| FAMAB-0053-CN | Human Anti-PRNP Recombinant Antibody (clone hu4.15) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B034(A) | Recombinant Anti-human PRNP Intrabody [(D-Arg)9] | IF, FC, WB, FuncS | scFv-(D-Arg)9 |
| IAB-B034(G) | Recombinant Anti-human PRNP Intrabody [+36 GFP] | WB, CO-IP, FuncS | scFv-(+36GFP) |
| IAB-B034(T) | Recombinant Anti-human PRNP Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-310 | Mouse Anti-PRNP Recombinant Antibody (clone POM2); scFv Fragment | WB, IHC, FuncS | Mouse scFv |
| FAMAB-0050-CN-S(P) | Chicken Anti-PRNP Recombinant Antibody (clone phAb4-31); scFv Fragment | ELISA | Chicken scFv |
| FAMAB-0051-CN-S(P) | Human Anti-PRNP Recombinant Antibody (clone hu4.00); scFv Fragment | ELISA | Humanized scFv |
| FAMAB-0052-CN-S(P) | Chicken Anti-PRNP Recombinant Antibody (clone ch4.31); scFv Fragment | ELISA | Chicken scFv |
| PABX-161-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone POM1); scFv Fragment | ELISA, IP, IHC, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-310 | Mouse Anti-PRNP Recombinant Antibody (clone POM2); Fab Fragment | WB, IHC, FuncS | Mouse Fab |
| HPAB-0282CQ-F(E) | Human Anti-PRNP Recombinant Antibody (clone boPrP-15); Fab Fragment | ELISA, WB | Human Fab |
| PFBC-254 | Mouse Anti-PRNP Recombinant Antibody (clone POM6); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0909-FY-S(P) | Mouse Anti-PRNP Recombinant Antibody scFv Fragment (HPAB-0909-FY-S(P)) | WB, ELISA | Mouse scFv |
| PABX-161-F(E) | Mouse Anti-PRNP Recombinant Antibody (clone POM1); Fab Fragment | ELISA, IP, IHC, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-026 | Recombinant Anti-Human PRNP VHH Single Domain Antibody (PNBL-026) | WB, ELISA, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-953LC | Anti-Human PRNP Recombinant Antibody (1A1) | FuncS, FC | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-942LC-S(P) | Anti-Sheep PRNP Recombinant Antibody scFv Fragment (6.1) | ELISA | Mouse antibody |
| MRO-948LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (6H10) | ELISA | Mouse antibody |
| MRO-949LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (31C6) | ELISA | Mouse antibody |
| MRO-950LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (72-5) | ELISA | Mouse antibody |
| PABX-161-F (E) | Recombinant Mouse Anti-PrP Antibody Fab Fragment (POM1) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-943LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (D13) | ELISA | Human antibody |
| MRO-944LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (D18) | ELISA | Human antibody |
| MRO-945LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (R72) | ELISA | Human antibody |
| MRO-946LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (R1) | ELISA | Human antibody |
| MRO-947LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (R2) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0727MZ | Chicken Anti-PRNP Polyclonal IgY | ICC, IF | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2871 | Hi-Affi™ Recombinant Rabbit Anti-PRNP Monoclonal Antibody (DS2871AB) | WB, FC, IHC-P, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0158CQ | Mouse Anti-PRNP Recombinant Antibody (clone 2A11) | WB, ELISA, IHC | Mouse IgG |
| EPAF-0268CQ | Mouse Anti-PRNP Recombinant Antibody (clone MA1-750) | ELISA | Mouse IgG |
| EPAF-0269CQ | Mouse Anti-PRNP Recombinant Antibody (clone D13) | ELISA, FC | Mouse IgG |
| EPAF-0270CQ | Mouse Anti-PRNP Recombinant Antibody (clone D18) | ELISA, FC | Mouse IgG |
| EPAF-0271CQ | Mouse Anti-PRNP Recombinant Antibody (clone R2) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY84 | Human Anti-PRNP (clone mAb132) scFv-Fc Chimera | ELISA, WB | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1763 | Anti-PRNP Immunohistochemistry Kit | IHC | |
| VS-0525-XY5727 | Anti-Human PRNP Immunohistochemistry Kit | IHC | |
| VS-0525-XY5728 | Anti-Mouse PRNP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC520 | Recombinant Anti-PRNP Vesicular Antibody, EV Displayed (VS-0425-YC520) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC150 | Recombinant Anti-PRNP (AA 56-90 x AA 83-89) Biparatopic Antibody, Tandem scFv (mAb 106 x mAb 110) | ELISA, IHC, WB | Tandem scFv |
| VS-0525-YC152 | Recombinant Anti-PRNP (AA 119-127 x AA 143-149) Biparatopic Antibody, Tandem scFv (mAb 132 x Clone 31C6) | ELISA, IHC, WB | Tandem scFv |
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