CTLA4 & CD40

Anti-CTLA4 & CD40 Products

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Anti-Human CTLA4 Recombinant Antibody (TAB-067) (TAB-067)
- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: WB, FuncS, IF, Neut, ELISA, FC, IP
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Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab)) (TAB-206)
- Derivation: Human
- Species Reactivity: Human
- Type: IgG2
- Application: WB, IF, IP, Neut, FuncS, ELISA, FC
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Anti-Human CD40 Recombinant Antibody (TAB-152) (TAB-152)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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Human Anti-CD40 Recombinant Antibody (TAB-126CL) (TAB-126CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: Block, Cyt, FuncS, Inhib
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Mouse Anti-CTLA4 Recombinant Antibody (TAB-195CL) (TAB-195CL)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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Human Anti-CD40 Recombinant Antibody (MOB-119CQ) (MOB-119CQ)
- Species Reactivity: Human
- Type: Human IgG2, κ
- Application: ELISA, IHC, IF, IP, FC, FuncS
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Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2422.H) (TAB-084MZ-F(E))
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.C) (TAB-085MZ-F(E))
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2422.C) (TAB-086MZ-F(E))
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-088MZ-F(E)) (TAB-088MZ-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-091MZ-F(E)) (TAB-091MZ-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-092MZ-F(E)) (TAB-092MZ-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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Mouse Anti-CD40 Recombinant Antibody (clone 27G1) (MOB-1269z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, FuncS
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Hamster Anti-Ctla4 Recombinant Antibody (clone YC082) (MOB-006LC)
- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: ELISA, FC
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Human Anti-CTLA4 Recombinant Antibody (MOB-061LC) (MOB-061LC)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FuncS
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Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.H) (TAB-083MZ-F(E))
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-202LC-F(E)) (TAB-202LC-F(E))
- Derivation: Chimeric (mouse/rhesus)
- Species Reactivity: Human, Rhesus
- Type: Chimeric antibody (mouse/rhesus)
- Application: FC, ELISA
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Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-203LC-F(E)) (TAB-203LC-F(E))
- Derivation: Chimeric (mouse/rhesus)
- Species Reactivity: Human, Rhesus
- Type: Chimeric antibody (mouse/rhesus)
- Application: FC, ELISA
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Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-204LC-F(E)) (TAB-204LC-F(E))
- Derivation: Phage display
- Species Reactivity: Human
- Type: Human Fab
- Application: SPR, ELISA
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Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-205LC-F(E)) (TAB-205LC-F(E))
- Derivation: Phage display
- Species Reactivity: Human
- Type: Human Fab
- Application: SPR, ELISA
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Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.H) (TAB-083MZ-S(P))
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.H) (TAB-084MZ-S(P))
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.C) (TAB-085MZ-S(P))
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.C) (TAB-086MZ-S(P))
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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Human Anti-CTLA4 Recombinant Antibody (clone 10D1) (HPAB-0051-YC)
- Species Reactivity: Human, Monkey
- Type: Human IgG, κ
- Application: ELISA, Cyt, Block
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Afuco™ Anti-Human CD40 ADCC Recombinant Antibody (APX005), ADCC Enhanced (AFC-120CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Afuco™ Anti-Human CTLA4 ADCC Recombinant Antibody (JMW-3B3), ADCC Enhanced (AFC-185CL)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Anti-CD40 Recombinant Antibody (Lucatumumab) (TAB-759)
- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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Anti-Human CD40 Recombinant Antibody (TAB-262) (TAB-262)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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Anti-Human CD40 Recombinant Antibody (hsPPAT-071-04) (TAB-0086CL)
- Type: Humanized Antibody
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-12) (TAB-0072CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-13) (TAB-0073CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-14) (TAB-0074CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-01) (TAB-0061CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-02) (TAB-0062CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-03) (TAB-0063CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-04) (TAB-0064CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-05) (TAB-0065CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Mouse Anti-CD40 Recombinant Antibody (TAB-209LC) (TAB-209LC)
- Species Reactivity: Human
- Type: Mouse IgG, κ
- Application: ELISA
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Anti-Human CD40 Recombinant Antibody (PPAT-071-02) (TAB-0062CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-03) (TAB-0063CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
Compare

Anti-Human CD40 Recombinant Antibody (PPAT-071-04) (TAB-0064CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-05) (TAB-0065CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-06) (TAB-0066CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-07) (TAB-0067CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-08) (TAB-0068CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-09) (TAB-0069CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-10) (TAB-0070CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-11) (TAB-0071CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-177LC-S(P)) (TAB-177LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-178LC-S(P)) (TAB-178LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-179LC-S(P)) (TAB-179LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-180LC-S(P)) (TAB-180LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-181LC-S(P)) (TAB-181LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-182LC-S(P)) (TAB-182LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-183LC-S(P)) (TAB-183LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
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Mouse Anti-Human CD40 Recombinant Antibody scFv Fragment (1.66) (TAB-184LC-S(P))
- Application: SPR, ELISA
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Anti-Human CD40 Recombinant Antibody scFv Fragment (2.36) (TAB-185LC-S(P))
- Application: SPR, ELISA
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Anti-Human CD40 Recombinant Antibody scFv Fragment (2.174) (TAB-186LC-S(P))
- Application: SPR, ELISA
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Recombinant Mouse Anti-Human CTLA4 Antibody F(ab')₂ Fragment, clone ANC152.2/8H5 (DrMAB-986)
- Species Reactivity: Human
- Type: F(ab')2
- Application: FC, EIA, FX, Bios
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Mouse Anti-CTLA4 Recombinant Antibody (clone ANC152.2/8H5); Fab Fragment (DrMAB-987)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA
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Anti-CTLA4 immunotoxin (scFv)-Mel (AGTO-G015M)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CTLA4 immunotoxin (scFv)-PE (AGTO-G015E)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CTLA4 immunotoxin (scFv)-Sap (AGTO-G015S)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CD40 immunotoxin (scFv)-PE (AGTO-G079E)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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10-FnIII scaffold protein anti-Human Cd40l (SFN-L034)
- Scaffold Name: 10-FnIII
- Target: Cd40l
- Species Reactivity: Human
- Derivation: Phage display
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Anti-Human CD40 Recombinant Antibody (PPAT-071-01) (TAB-0061CL)
- Species Reactivity: Human, Monkey
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-23) (TAB-0083CL)
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, ADCC, CDC, FuncS
Compare

Anti-Human CD40 Recombinant Antibody (PPAT-071-24) (TAB-0084CL)
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, ADCC, CDC, FuncS
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Anti-Human CD40 Recombinant Antibody (PPAT-071-25) (TAB-0085CL)
- Species Reactivity: Cross-react with cynomolgus CD40
- Application: ELISA, ADCC, CDC, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-01) (TAB-0061CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-02) (TAB-0062CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-03) (TAB-0063CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-04) (TAB-0064CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-05) (TAB-0065CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-06) (TAB-0066CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-07) (TAB-0067CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-08) (TAB-0068CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-09) (TAB-0069CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-10) (TAB-0070CL-F(E))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-15) (TAB-0075CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
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Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-16) (TAB-0076CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-17) (TAB-0077CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-18) (TAB-0078CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-19) (TAB-0079CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-20) (TAB-0080CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-21) (TAB-0081CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-22) (TAB-0082CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-23) (TAB-0083CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-24) (TAB-0084CL-S(P))
- Species Reactivity: Cross-react with mouse CD40
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-06) (TAB-0066CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-07) (TAB-0067CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-08) (TAB-0068CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-09) (TAB-0069CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-10) (TAB-0070CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
Compare

Anti-Human CD40 Recombinant Antibody scFv Fragment (PPAT-071-11) (TAB-0071CL-S(P))
- Species Reactivity: Human, Monkey
- Application: ELISA, FuncS
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Anti-Human CTLA4 Recombinant Antibody Fab Fragment (Mu-26B) (TAB-093MZ-F(E))
- Application: ELISA
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Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-089MZ-F(E)) (TAB-089MZ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-090MZ-F(E)) (TAB-090MZ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-087MZ-F(E)) (TAB-087MZ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.

Background

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

CD40 (CD40 Molecule) is a Protein Coding gene. Diseases associated with CD40 include Immunodeficiency With Hyper-Igm, Type 3 and Cd40 Ligand Deficiency. Among its related pathways are NLR Proteins and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include enzyme binding and receptor activity. An important paralog of this gene is TNFRSF11A.

Related Diseases

Asthma

Rheumatoid Arthritis

Systemic Lupus Erythematosus

Primary Immunodeficiency

Allograft Rejection

Autoimmune Thyroid Disease