Anti-Human CD40 Recombinant Antibody (PPAT-071-14) (CAT#: TAB-0074CL)
Anti-human CD40 monoclonal antibody is a monoclonal antibody that binds to CD40 which is a membrane glycoprotein expressed on the human B cell surface, the humanized anti-human CD40 monoclonal antibody can exhibits even greater ADCC activity without the stimulatory activity.
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Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
Specifications
- Immunogen
- CD40/NIH3T3
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Cross-react with mouse CD40
- Clone
- PPAT-071-14
- Related Disease
- Tumors expressing human CD40
Target
- Alternative Names
- CD40; CD40 molecule, TNF receptor superfamily member 5; p50; Bp50; CDW40; TNFRSF5; tumor necrosis factor receptor superfamily member 5; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); nerve growth factor receptor-related B-lymphocyte activation molecule
- Gene ID
- 958
- UniProt ID
- P25942
Related Resources
Asthma
Systemic Lupus Erythematosus
Primary Immunodeficiency
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-262 | Anti-Human CD40 Recombinant Antibody (TAB-262) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 |
| TAB-188LC-S(P) | Anti-Human CD40 Recombinant Antibody scFv Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
| TAB-192LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-192LC-S(P)) | ELISA | Mouse scFv |
| TAB-193LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-193LC-S(P)) | ELISA | Mouse scFv |
| TAB-202LC-S(P) | Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-202LC-S(P)) | FC, ELISA | scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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