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APC-A*02:01/Human CD33 A65Y (YIISGDSPV) MHC Tetramer (CAT#: MHC-LC164)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CD33 A65Y-derived peptide of YIISGDSPV sequence covering 65-73 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line PC-3
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64807/1186_A4_3_selected.jpg
Figure 2 IHC staining of human lymph node
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows membranous and cytoplasmic positivity in germinal center cells and non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35832/113039_A_9_8_selected.jpg
Figure 3 IHC staining of human tonsil
Figure 3 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows cytoplasmic positivity in germinal center cells and non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11442/26430_A_6_8_selected.jpg
Figure 4 IF staining of human cell line RH-30
Figure 4 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64807/1413_G6_1_red_green.jpg
Figure 5 IF staining of human cell line U-2 OS
Figure 5 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64807/1200_A4_2_red_green.jpg
Normal Tissue
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79996/170702_A_9_5.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79996/170702_A_9_8.jpg
Figure 8 Spleen
Figure 8 Spleen
(Cells in red pulp
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79996/170702_B_8_4.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, NB-4, RPMI-8226, THP-1, U-937)
Figure 9 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, NB-4, RPMI-8226, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105383-CD33

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • CD33 A65Y
  • Antigen Species
  • Human
  • Peptide
  • YIISGDSPV
  • Range
  • 65-73
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins.
  • Alternative Names
  • CD33; CD33 molecule; p67; SIGLEC3; SIGLEC-3

Downloads

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See other products for "CD33"

Single-domain Antibody

CAT Product Name Application Type
NAB-321-sdAb Recombinant Anti-human CD33 VHH Single Domain Antibody WB, IP, ChiP, Neut, ELISA Llama VHH

Humanized Antibody

CAT Product Name Application Type
TAB-013 Humanized Anti-CD33 Recombinant Antibody (clone Gemtuzumab) IF, IP, Neut, FuncS, ELISA, FC, WB Humanized (from mouse) IgG4, κ
TAB-H37 Anti-Human CD33 Recombinant Antibody (Gemtuzumab Ozogamicin) ELISA, FC, IP, FuncS, IF, Neut, IHC IgG
TAB-756 Anti-CD33 Recombinant Antibody (Lintuzumab) IF, IP, Neut, FuncS, ELISA, FC, ICC IgG1 - kappa
VS3-WK1523 Human Anti-CD33 Recombinant Antibody (clone CDP-771) FC Humanized IgG4

Immunotoxin

CAT Product Name Application Type
AGTO-G008E Anti-CD33 immunotoxin (scFv)-PE Cytotoxicity assay, Function study
AGTO-G008G Anti-CD33 immunotoxin (scFv)-Gel Cytotoxicity assay, Function study
AGTO-L050E anti-CD33 immunotoxin M195 (IgG)-PE Cytotoxicity assay, Functional assay
AGTO-L050G anti-CD33 immunotoxin M195 (IgG)-Gel Cytotoxicity assay, Functional assay

Human Antibody

CAT Product Name Application Type
TAB-123LC Anti-Human CD33 Recombinant Antibody FC Human antibody
TAB-146LC Human Anti-CD33 Recombinant Antibody (TAB-146LC) ELISA Human IgG
TAB-123LC-S(P) Anti-Human CD33 Recombinant Antibody scFv Fragment FC Human antibody
TAB-146LC-S(P) Human Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-146LC-S(P)) ELISA Human scFv
TAB-123LC-F(E) Anti-Human CD33 Recombinant Antibody Fab Fragment FC Human antibody

Mouse Antibody

CAT Product Name Application Type
TAB-143LC Mouse Anti-CD33 Recombinant Antibody (TAB-143LC) ELISA, FC Mouse IgG
TAB-144LC Mouse Anti-CD33 Recombinant Antibody (TAB-144LC) ELISA, FC Mouse IgG
TAB-145LC Human Anti-CD33 Recombinant Antibody (TAB-145LC) ELISA, FC Human IgG
TAB-147LC Mouse Anti-CD33 Recombinant Antibody (TAB-147LC) FC Mouse IgG
TAB-133LC-F(E) Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-133LC-F(E)) ELISA, FC Mouse Fab

Fab Glycosylation

CAT Product Name Application Type
Gly-013LC Recombinant Anti-Human CD33 Antibody (Fab glycosylation) ELISA Humanized antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-341CQ Mouse Anti-CD33 Recombinant Antibody (clone WM53) FC, IHC-Fr, ICC, IP, WB, Block Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0553 Hi-Affi™ Rabbit Anti-CD33 Recombinant Antibody (clone DS553AB) WB, ICC, IP Rabbit IgG

Chimeric Antibody

CAT Product Name Application Type
TAB-471CQ Anti-Human CD33 Recombinant Antibody (Vadastuximab) ELISA, IHC, FC, IP, IF, FuncS IgG1, κ

Recombinant Antibody

CAT Product Name Application Type
FAMAB-0045CQ Human Anti-CD33 Recombinant Antibody (clone huM195) ELISA, FC, FuncS Humanized IgG1
HPAB-M0471-YC Human Anti-CD33 Recombinant Antibody (HPAB-M0471-YC) FuncS Humanized IgG
HPAB-1910LY Human Anti-CD33 Recombinant Antibody (HPAB-1910LY) FC, Inhib, FuncS Humanized IgG
HPAB-1911LY Human Anti-CD33 Recombinant Antibody (HPAB-1911LY) FC, SPR, FuncS Humanized IgG
HPAB-1912LY Human Anti-CD33 Recombinant Antibody (HPAB-1912LY) FC Humanized IgG

scFv Fragment Antibody

CAT Product Name Application Type
FAMAB-0045CQ-S(P) Human Anti-CD33 Recombinant Antibody (clone huM195); scFv Fragment ELISA, FC Humanized scFv
HPAB-0087-FY-S(P) Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0087-FY-S(P)) ELISA Human scFv
HPAB-676-FY-S(P) Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-676-FY-S(P)) FC Mouse scFv
HPAB-M0470-YC-S(P) Human Anti-CD33 Recombinant Antibody (clone Lintuzumab); scFv Fragment FuncS Humanized scFv
HPAB-M0471-YC-S(P) Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-M0471-YC-S(P)) FuncS Humanized scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-M0470-YC-F(E) Human Anti-CD33 Recombinant Antibody (clone Lintuzumab); Fab Fragment FuncS Humanized Fab
HPAB-M0471-YC-F(E) Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-M0471-YC-F(E)) FuncS Humanized Fab
HPAB-2047LY-F(E) Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-2047LY-F(E)) FC, ELISA Humanized Fab
HPAB-2048LY-F(E) Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-2048LY-F(E)) FC, ELISA Humanized Fab
HPAB-2049LY-F(E) Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-2049LY-F(E)) FC, ELISA Humanized Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-471CQ Afuco™ Anti-CD33 ADCC Recombinant Antibody (Vadastuximab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-756 Afuco™ Anti-CD33 ADCC Recombinant Antibody (Lintuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-013 Afuco™ Anti-CD33 ADCC Recombinant Antibody (Gemtuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN0509 PE-A*02:01/Human CD33 (YLISGDSPV) MHC Tetramer FCM, IHC
MHC-CN0510 APC-A*02:01/Human CD33 (YLISGDSPV) MHC Tetramer FCM, IHC
MHC-CN0511 FITC-A*02:01/Human CD33 (YLISGDSPV) MHC Tetramer FCM, IHC
MHC-CN0512 A*02:01/Human CD33 (YLISGDSPV) MHC Tetramer FCM, IHC
MHC-YF358 A*02:01/Human CD33 65-73 (1Y2L) (YLISGDSPV) MHC Pentamer FCM

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