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    Recombinant Anti-human CD33 VHH Single Domain Antibody

    CAT#: NAB-321-sdAb

    Anti-human CD33 VHH Single Domain Antibody is a recombinant protein produced in E. coli.

    Gene Expression
    ❮
    Figure 1 IF staining of human cell line PC-3 Figure 2 IHC staining of human lymph node Figure 3 IHC staining of human tonsil Figure 4 IF staining of human cell line RH-30 Figure 5 IF staining of human cell line U-2 OS Figure 6 Kidney Figure 7 Lymph node Figure 8 Spleen Figure 9 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, NB-4, RPMI-8226, THP-1, U-937)
    ❯

    Specifications

    • Immunogen
    • human CD33 molecule
    • Host Species
    • Llama
    • Type
    • Llama VHH
    • Species Reactivity
    • Human
    • Molecule Class
    • VHH Single Domain Antibody
    • Applications
    • This product is suitable for use in WB, IP, ChiP, Neut, ELISA and most other immunological methods.

    Product Property

    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Target

    • Alternative Names
    • CD33; CD33 molecule; p67; SIGLEC3; SIGLEC-3
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    Breast cancer biomarkers at key points during disease progression
    Promising results
    The results with the Recombinant Anti-human CD33 VHH Single Domain Antibody have been very promising. The leukemic cell counts have significantly decreased, and the side effects are minimal.
    Breast cancer biomarkers at key points during disease progression
    Excellent for ELISA
    I've been using the antibody in my laboratory for ELISA tests, and it's been a game-changer. The binding affinity and specificity for human CD33 molecule are excellent.
    Breast cancer biomarkers at key points during disease progression Emily Parker
    09.Apr,22
    High specificity and low background for IA
    The recombinant Anti-human CD33 VHH Single Domain Antibody exceeded our expectations. The high specificity and low background have significantly improved the quality of our immunoassays.

    Q&As

    1. What is the Recombinant Anti-human CD33 VHH Single Domain Antibody's major application?

      A: The primary use of the Recombinant Anti-human CD33 VHH Single Domain Antibody is to target and treat acute myeloid leukemia (AML) by binding specifically to the CD33 antigen on leukemic cells, facilitating their identification and destruction by the immune system, while sparing healthy cells.

    2. Does the Recombinant Anti-human CD33 VHH Single Domain Antibody have any contraindications when used?

      A: Contraindications may include individuals with known hypersensitivity to any components of the antibody formulation. It should also be used with caution in patients with severe pre-existing conditions that could be exacerbated by the treatment. Consulting a healthcare provider is essential to assess individual suitability.

    3. How is harm to healthy cells reduced by the Recombinant Anti-human CD33 VHH Single Domain Antibody?

      A: The antibody's small size and specificity for the CD33 antigen allow it to bind only to leukemic cells, sparing most healthy cells. This specificity reduces the broad, systemic toxicity commonly associated with traditional treatments, resulting in fewer and less severe side effects.

    View the frequently asked questions answered by Creative Biolabs Support.

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    Downloadable Resources

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - NAB-321-sdAb.pdf

    MSDS

    MSDS - NAB-321-sdAb.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

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