Anti-CD19 fully human monoclonal antibody MDX-1342 (CAT#: Gly-011CL)

A fully human anti-CD19 monoclonal antibody directed against the B-cell-specific membrane protein CD-19 with potential antineoplastic activity. Anti-CD19 monoclonal antibody MDX-1342 binds to CD19, depleting and eliminating CD19-expressing B-cells. CD19 is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages.

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Specifications

  • Type
  • Fully human Ab
  • Class
  • Antineoplastics; Antirheumatics; Monoclonal antibodies
  • Mechanism of action
  • CD19 antigen inhibitors

Related Resources

  • Related Diseases

Downloads

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See other products for "CD19"

Humanized Antibody

CAT Product Name Application Type
TAB-891 Humanized Anti-CD19 Recombinant Antibody (clone Denintuzumab) ELISA, FC, IP, FuncS, IF, Neut, ICC Humanized IgG1, κ
TAB-1625CL Anti-Human CD19 Recombinant Antibody (396) Depletion, ELISA Humanized antibody
TAB-1612CL-S(P) Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1612CL-S(P)) Depletion, FuncS Humanized scFv
TAB-1625CL-S(P) Anti-Human CD19 Recombinant Antibody scFv Fragment (396) Depletion, ELISA Humanized antibody
TAB-431CQ Anti-Human CD19 Recombinant Antibody ELISA, IHC, FC, IP, IF, FuncS IgG1, κ

Immunotoxin

CAT Product Name Application Type
AGTO-L047E anti-CD19 immunotoxin HD37 (scFv)-PE Cytotoxicity assay, Functional assay
AGTO-L047D anti-CD19 immunotoxin HD37 (scFv)-DT Cytotoxicity assay, Functional assay
AGTO-L047R anti-CD19 immunotoxin HD37 (scFv)-RTA Cytotoxicity assay, Functional assay
AGTO-L047S anti-CD19 immunotoxin HD37 (scFv)-Sap Cytotoxicity assay, Functional assay
AGTO-L047P anti-CD19 immunotoxin HD37 (scFv)-PAP Cytotoxicity assay, Functional assay

Human Antibody

CAT Product Name Application Type
TAB-108CL Anti-Human CD19 Recombinant Antibody (MDX-1342) FC, ADCC, FuncS Antibody
TAB-1616CL-F(E) Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1616CL-F(E)) ELISA, WB Human Fab
TAB-1617CL-F(E) Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1617CL-F(E)) ELISA, WB Human Fab
TAB-1626CL-F(E) Anti-Human CD19 Recombinant Antibody Fab Fragment (HB12a) Depletion Fully human antibody
TAB-1627CL-F(E) Anti-Human CD19 Recombinant Antibody Fab Fragment (HB12b) Depletion Fully human antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-1613CL Human Anti-CD19 Recombinant Antibody (TAB-1613CL) Cyt, FC, FuncS, Inhib Chimeric (mouse/human) IgG1
TAB-1621CL Anti-Human CD19 Recombinant Antibody (cHD37) ADCC, FuncS Chimeric antibody (mouse/human)
TAB-1613CL-S(P) Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1613CL-S(P)) Depletion, FuncS Mouse scFv
TAB-1614CL-S(P) Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1614CL-S(P)) FuncS Mouse scFv
TAB-1621CL-S(P) Anti-Human CD19 Recombinant Antibody scFv Fragment (cHD37) FuncS Chimeric antibody (mouse/human)

Mouse Antibody

CAT Product Name Application Type
TAB-1611CL-F(E) Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1611CL-F(E)) Depletion, FuncS Mouse Fab
TAB-1620CL-F(E) Anti-Human CD19 Recombinant Antibody Fab Fragment (HD37) FuncS
TAB-1622CL-F(E) Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1622CL-F(E)) ELISA, FC, Apop, ADCC, FuncS Mouse Fab
TAB-1623CL-F(E) Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1623CL-F(E)) ELISA, FC Mouse Fab
TAB-1624CL-F(E) Anti-Human CD19 Recombinant Antibody Fab Fragment (381) FC, Inhib, ELISA

Fc Glycosylation

CAT Product Name Application Type
Gly-061LC Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Low fucosylated) ELISA, FC Chimeric antibody (mouse/human)
Gly-105LC Recombinant Anti-Human CD19 Antibody (Fc glycosylation) ELISA Mouse antibody
Gly-141LC Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Non fucosylated) ELISA Humanized antibody

Low- or Non-fucosylated Oligosaccharide

CAT Product Name Application Type
Gly-061LC-1 Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Low fucosylated) ELISA, FC Chimeric antibody (mouse/human)
Gly-141LC-1 Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Non fucosylated) ELISA Humanized antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0100MZ Chicken Anti-CD19 Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-286CQ Mouse Anti-CD19 Recombinant Antibody (clone SJ25-C1) Neut, FC, IHC, IHC-Fr, IP Mouse IgG1
NEUT-287CQ Mouse Anti-CD19 Recombinant Antibody (clone HIB19) FC, CyTOF, IHC, Block Mouse IgG1, κ

Blocking Antibody

CAT Product Name Application Type
NEUT-288CQ Rat Anti-CD19 Recombinant Antibody (clone 1D3) Depletion, Block, FC Rat IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0538 Hi-Affi™ Rabbit Anti-CD19 Recombinant Antibody (clone DS538AB) IHC-P Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0458LY Human Anti-CD19 Recombinant Antibody (clone CBL001LY) FC Human IgG1
HPAB-0459LY Human Anti-CD19 Recombinant Antibody (clone 1) ELISA Humanized IgG1
HPAB-0460LY Human Anti-CD19 Recombinant Antibody (clone 2) ELISA Humanized IgG1
HPAB-0461LY Human Anti-CD19 Recombinant Antibody (clone 3) ELISA Humanized IgG1
HPAB-0463LY Mouse Anti-CD19 Recombinant Antibody (clone CBL002LY) FC, in vitro cytotoxic, ELISA Mouse IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0023LY-F(E) Humanized Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0023LY-F(E)) WB Fab
HPAB-0036LY-F(E) Humanized Anti-CD19 Antibody Fab Fragment (Hbu12) WB Fab
HPAB-0418LY-F(E) Human Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0418LY-F(E)) ELISA, WB, FC, RIA Human Fab
HPAB-0419LY-F(E) Human Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0419LY-F(E)) ELISA, WB, FC, RIA Human Fab
HPAB-0420LY-F(E) Human Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0420LY-F(E)) ELISA, WB, FC, RIA Human Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-174 Afuco™ Anti-CD19 ADCC Recombinant Antibody (Taplitumomab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-2977LY-S(P) Human Anti-CD19 Recombinant Antibody (clone 1F1); scfv Fragment ELISA, FC Human scfv
HPAB-2978LY-S(P) Human Anti-CD19 Recombinant Antibody (clone 1H11); scfv Fragment ELISA, FC Human scfv
HPAB-3158LY-S(P) Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (HPAB-3158LY-S(P)) ELISA Mouse scfv
FAMAB-0071WJ-S(P) Mouse Anti-CD19 Recombinant Antibody (clone 25C1); scFv Fragment WB, FC Human scFv
FAMAB-0072WJ-S(P) Mouse Anti-CD19 Recombinant Antibody (clone BLY3); scFv Fragment WB, FC Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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