CD19
CD19 (CD19 Molecule) is a Protein Coding gene. Diseases associated with CD19 include Immunodeficiency, Common Variable, 3 and Common Variable Immunodeficiency. Among its related pathways are RET signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include signal transducer activity, downstream of receptor.
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, FuncS
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: Depletion, Block, FC
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- Species Reactivity: Human, Chimpanzee
- Type: Mouse IgG1, κ
- Application: FC, CyTOF, IHC, Block
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, FC, IHC, IHC-Fr, IP
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: Cyt, FuncS, FC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human IgG1
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized IgG
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized IgG
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1, κ
- Application: ELISA, IHC, FC, IP, IF, FuncS
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Asn297 in Fc region
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Asn297 in Fc region
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- Host Species: Mouse
- Specificity: Human
- Type: Mouse antibody
- Glycosylation site: Fc region
- Glycoform (ratio): G2-NANA
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- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): GN-GN-M-(M-GN)2
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- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): GN-GN-M-(M-GN)2
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- Type: Fully human antibody
- Application: Depletion
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- Type: Fully human antibody
- Application: Depletion
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Depletion, ELISA
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- Application: FC, Inhib, ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, Apop, ADCC, FuncS
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: Depletion, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Depletion, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Depletion, FuncS
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- Type: Fully human antibody
- Application: Depletion
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- Type: Fully human antibody
- Application: Depletion
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Depletion, ELISA
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- Application: FC, Inhib, ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, Apop, ADCC, FuncS
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FuncS
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: Depletion, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Depletion, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Depletion, FuncS
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- Type: Fully human antibody
- Application: Depletion
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- Type: Fully human antibody
- Application: Depletion
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Depletion, ELISA
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- Application: FC, Inhib, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, Apop, ADCC, FuncS
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ADCC, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: Cyt, FC, FuncS, Inhib
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: Depletion, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: Depletion, FuncS
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- Target: CD19
- Linker: mc-vc (maleimidocaproyl-valine-alanine)
- Drug: pyrrolobenzodiazepine (PBD) dimers SGD-1882
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- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD19
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD19
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
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- Target: CD19
- Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD19
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD19
- Linker: VC (valine-citrulline)
- Drug: duocarmycin
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- Target: CD19
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD19
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD19
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Target: CD19
- Linker: VC-PAB (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Derivation: Human
- Species Reactivity: Human
- Type: Antibody
- Application: FC, ADCC, FuncS
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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