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CD19

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Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Derivation:
Mouse
Species Reactivity:
Human
Type:
(scFv - kappa - heavy) - (scFv - heavy - kappa)
Application:
IF, IP, Neut, FuncS, ELISA, FC, ICC
Species Reactivity:
Human
Application:
Cytotoxicity assay, Function study
Species Reactivity:
Human
Application:
Cytotoxicity assay, Function study
Species Reactivity:
Human
Application:
Cytotoxicity assay, Function study
Species Reactivity:
Human
Application:
Cytotoxicity assay, Function study
Species Reactivity:
Human
Application:
Cytotoxicity assay, Function study
Target:
CD19
Linker:
VC-PAB (valine-citrulline-p-aminobenzoyloxycarbonyl)
Drug:
MMAE (Monomethyl auristatin E)
Target:
CD19
Linker:
Mc (maleimidocaproyl)
Drug:
MMAF (Monomethyl auristatin F)
Target:
CD19
Linker:
Mc (maleimidocaproyl)
Drug:
MMAF (Monomethyl auristatin F)
Target:
CD19
Linker:
Mc (maleimidocaproyl)
Drug:
MMAE (Monomethyl auristatin E)
Target:
CD19
Linker:
SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
Drug:
DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
CD19
Linker:
Mc (maleimidocaproyl)
Drug:
MMAF (Monomethyl auristatin F)
Target:
CD19
Linker:
mc (maleimidocaproyl)
Drug:
MMAF (monomethyl auristatin F)
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
ELISA, IP, FC, FuncS, Neut, IF, ICC
Derivation:
Chimeric
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
IF, IP, Neut, FuncS, ELISA, FC, ICC
Derivation:
Humanized
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
IF, IP, Neut, FuncS, ELISA, FC, WB
Derivation:
Humanized
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
ELISA, FC, IP, FuncS, IF, Neut, ICC
Targets:
CD19 & CD3
Type:
BiTE
Application:
FuncS, Promising therapeutic agent
Targets:
CD19 & FcαR
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
CD19 & FcγRI
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
FcγRI & CD19
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
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