Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Low fucosylated) (CAT#: Gly-061LC-1)
This product is a chimeric (mouse/human) monoclonal antibody with N-glycosylation site in the Fc region. The antibody chR005-1 F20 with enhanced ADCC specifically binds human CD19 and can be potentially used in the treatment of B-cell malignancy.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_7_3.jpg
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_7_3.jpg
Figure 2 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_5_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_5_6.jpg
Figure 3 Appendix
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_2_2.jpg
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_2_2.jpg
Figure 4 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177455-CD19
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177455-CD19
Glyco-engineering
- Glycosylation site
- Asn297 in Fc region
- Glycoform (ratio)
- GN-GN-M-(M-GN)2
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced ADCC
Specifications
- Target
- CD19 (Cluster of differentiation-19)
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Antibody Isotype
- IgG1
- Clone
- chR005-1 F20
- Applications
- ELISA, FC
Target
- Alternative Names
- CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4;
- Related Disease
- B-cell malignancy
- Gene ID
- 930
- UniProt ID
- P15391
Related Resources
Primary Immunodeficiency
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone chR005-1 F20"
See other products for "CD19"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1087z | Mouse Anti-CD19 Recombinant Antibody (clone 32B9) | WB, FC, ICC, IF, FuncS | Mouse IgG1 |
| HPAB-0264-CN | Human Anti-CD19 Recombinant Antibody (HPAB-0264-CN) | ELISA, FC | Humanized IgG1, κ |
| HPAB-0265-CN | Human Anti-CD19 Recombinant Antibody (HPAB-0265-CN) | ELISA, FC | Humanized IgG1, κ |
| HPAB-0266-CN | Human Anti-CD19 Recombinant Antibody (HPAB-0266-CN) | ELISA, FC | Humanized IgG |
| HPAB-0267-CN | Human Anti-CD19 Recombinant Antibody (HPAB-0267-CN) | ELISA, FC | Humanized IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H17 | Anti-Human CD19 Recombinant Antibody (Denintuzumab Mafodotin) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-891 | Humanized Anti-CD19 Recombinant Antibody (clone Denintuzumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | Humanized IgG1, κ |
| TAB-1612CL | Human Anti-CD19 Recombinant Antibody (TAB-1612CL) | Depletion, FuncS | Humanized IgG1 |
| TAB-1612CL-F(E) | Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1612CL-F(E)) | Depletion, FuncS | Humanized Fab |
| TAB-1625CL-F(E) | Anti-Human CD19 Recombinant Antibody Fab Fragment (396) | Depletion, ELISA | Humanized antibody |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L047E | anti-CD19 immunotoxin HD37 (scFv)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L047D | anti-CD19 immunotoxin HD37 (scFv)-DT | Cytotoxicity assay, Functional assay | |
| AGTO-L047R | anti-CD19 immunotoxin HD37 (scFv)-RTA | Cytotoxicity assay, Functional assay | |
| AGTO-L047S | anti-CD19 immunotoxin HD37 (scFv)-Sap | Cytotoxicity assay, Functional assay | |
| AGTO-L047P | anti-CD19 immunotoxin HD37 (scFv)-PAP | Cytotoxicity assay, Functional assay |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1611CL | Mouse Anti-CD19 Recombinant Antibody (TAB-1611CL) | Depletion, FuncS | Mouse IgG2a, κ |
| TAB-1620CL | Anti-Human CD19 Recombinant Antibody (HD37) | FuncS | |
| TAB-1622CL | Mouse Anti-CD19 Recombinant Antibody (TAB-1622CL) | ELISA, FC, Apop, ADCC, FuncS | Mouse IgG |
| TAB-1623CL | Mouse Anti-CD19 Recombinant Antibody (TAB-1623CL) | ELISA, FC | Mouse IgG |
| TAB-1624CL | Anti-Human CD19 Recombinant Antibody (381) | FC, Inhib, ELISA |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1626CL | Anti-Human CD19 Recombinant Antibody (HB12a) | Depletion | Fully human antibody |
| TAB-1627CL | Anti-Human CD19 Recombinant Antibody (HB12b) | Depletion | Fully human antibody |
| TAB-1616CL-S(P) | Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1616CL-S(P)) | ELISA, WB | Human scFv |
| TAB-1626CL-S(P) | Anti-Human CD19 Recombinant Antibody scFv Fragment (HB12a) | Depletion | Fully human antibody |
| TAB-1627CL-S(P) | Anti-Human CD19 Recombinant Antibody scFv Fragment (HB12b) | Depletion | Fully human antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1613CL-S(P) | Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1613CL-S(P)) | Depletion, FuncS | Mouse scFv |
| TAB-1621CL-S(P) | Anti-Human CD19 Recombinant Antibody scFv Fragment (cHD37) | FuncS | Chimeric antibody (mouse/human) |
| TAB-1613CL-F(E) | Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1613CL-F(E)) | Depletion, FuncS | Chimeric (mouse/human) Fab |
| TAB-1614CL-F(E) | Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1614CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| TAB-1621CL-F(E) | Anti-Human CD19 Recombinant Antibody Fab Fragment (cHD37) | FuncS | Chimeric antibody (mouse/human) |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-061LC | Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Low fucosylated) | ELISA, FC | Chimeric antibody (mouse/human) |
| Gly-105LC | Recombinant Anti-Human CD19 Antibody (Fc glycosylation) | ELISA | Mouse antibody |
| Gly-141LC | Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Low- or Non-fucosylated Oligosaccharide
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-141LC-1 | Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0100MZ | Chicken Anti-CD19 Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-286CQ | Mouse Anti-CD19 Recombinant Antibody (clone SJ25-C1) | Neut, FC, IHC, IHC-Fr, IP | Mouse IgG1 |
| NEUT-287CQ | Mouse Anti-CD19 Recombinant Antibody (clone HIB19) | FC, CyTOF, IHC, Block | Mouse IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-288CQ | Rat Anti-CD19 Recombinant Antibody (clone 1D3) | Depletion, Block, FC | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0538 | Hi-Affi™ Rabbit Anti-CD19 Recombinant Antibody (clone DS538AB) | IHC-P | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0117LY-S(P) | Human Anti-CD19 Recombinant Antibody; scFv Fragment (HPAB-0117LY-S(P)) | ELISA | Humanized scfv |
| HPAB-0707-FY-F(E) | Mouse Anti-CD19 Recombinant Antibody (clone AB006); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0421-WJ-S(P) | Human Anti-CD19 Recombinant Antibody; scFv Fragment (HPAB-0421-WJ-S(P)) | ELISA | Human scFv |
| FAMAB-0071WJ-S(P) | Mouse Anti-CD19 Recombinant Antibody (clone 25C1); scFv Fragment | WB, FC | Human scFv |
| FAMAB-0072WJ-S(P) | Mouse Anti-CD19 Recombinant Antibody (clone BLY3); scFv Fragment | WB, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0023LY-F(E) | Humanized Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0023LY-F(E)) | WB | Fab |
| HPAB-0036LY-F(E) | Humanized Anti-CD19 Antibody Fab Fragment (Hbu12) | WB | Fab |
| HPAB-0418LY-F(E) | Human Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0418LY-F(E)) | ELISA, WB, FC, RIA | Human Fab |
| HPAB-0419LY-F(E) | Human Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0419LY-F(E)) | ELISA, WB, FC, RIA | Human Fab |
| HPAB-0420LY-F(E) | Human Anti-CD19 Recombinant Antibody; Fab Fragment (HPAB-0420LY-F(E)) | ELISA, WB, FC, RIA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-174 | Afuco™ Anti-CD19 ADCC Recombinant Antibody (Taplitumomab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for Gly-061LC-1. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.