Recombinant Anti-Human CD19 Antibody (Fc glycosylation) (CAT#: Gly-105LC)
This product is a mouse monoclonal antibody with glycosylation site in Fc region. The antibody with reduced anti-drug immune responsespecifically binds human CD19 and can be potentially used in the treatment of autoimmune disease and bone disease.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_7_3.jpg
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_7_3.jpg
Figure 2 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_5_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_5_6.jpg
Figure 3 Appendix
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_2_2.jpg
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_2_2.jpg
Figure 4 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177455-CD19
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177455-CD19
Glyco-engineering
- Glycosylation site
- Fc region
- Glycoform (ratio)
- G2-NANA
- Glycosylation Type
- N-glycosylation
- Activity
- Reduced anti-drug immune response
Specifications
- Target
- CD19 (Cluster of differentiation-19)
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- Human
- Applications
- ELISA
Target
- Alternative Names
- CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4;
- Related Disease
- Autoimmune disease and bone disease
- Gene ID
- 930
- UniProt ID
- P15391
Related Resources
Primary Immunodeficiency
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Immunotoxins
Humanized Antibodies
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NHP Antibodies
FC Reagents & Kits
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Extracellular Vesicle Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G076E | Anti-CD19 immunotoxin HD37 (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-G076D | Anti-CD19 immunotoxin HD37 (IgG)-DT | Cytotoxicity assay, Function study | |
| AGTO-G076R | Anti-CD19 immunotoxin HD37 (IgG)-RTA | Cytotoxicity assay, Function study | |
| AGTO-G076S | Anti-CD19 immunotoxin HD37 (IgG)-Sap | Cytotoxicity assay, Function study | |
| AGTO-G076P | Anti-CD19 immunotoxin HD37 (IgG)-PAP | Cytotoxicity assay, Function study |
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For Research Use Only. Not For Clinical Use.
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