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  • Anti-Human CD44 Recombinant Antibody Fab Fragment (14G9.B8.B4)

Anti-Human CD44 Recombinant Antibody Fab Fragment (14G9.B8.B4) (CAT#: TAB-229LC-F(E))

Recombinant monoclonal antibody to CD44. 14G9.B8.B4 is a human antibody that can be potentially used in the treatment of inflammatory disease and autoimmune disease.

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Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
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Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/316/203_H10_1_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/112/if_selected.jpg
Figure 3 IHC staining of human vagina
Figure 3 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/316/5_B_2_2_selected.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Enterocytes
Staining: Medium
Intensity: Strong
Quantity: <25%
Goblet cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity:>75%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_A_9_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_A_8_5.jpg
Figure 6 Skin
Figure 6 Skin
(Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in spinous layer
Staining: High
Intensity: Strong
Quantity:>75%
Fibrohistiocytic cells
Staining: High
Intensity: Strong
Langerhans cells
Staining: High
Intensity: Strong
Quantity:>75%
Lymphocytes
Staining: High
Intensity: Strong
Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_B_7_1.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000026508-CD44
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000026508-CD44

Specifications

  • Immunogen
  • THP-1 cell, Recombinant CD44-Fc, 300-19 transfectants expressing human CD44
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • 14G9.B8.B4
  • Applications
  • FC, ELISA
  • Related Disease
  • Inflammatory disease, Autoimmune disease

Target

  • Alternative Names
  • IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; CD44

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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CAT Product Name Application Type
DrMAB-991 Mouse Anti-CD44 Recombinant Antibody (clone BU52) IHC, WB, IP, Inhib, Stim Mouse IgG1 F(ab')2, κ
HPAB-0154-FY-F(E) Human Anti-CD44 Recombinant Antibody (clone (hu)ARH460-16-2 variant HV2/KV1); Fab Fragment Inhib Humanized Fab
HPAB-0746-FY-S(P) Human Anti-CD44 Recombinant Antibody; scFv Fragment (HPAB-0746-FY-S(P)) ELISA Human scFv
HPAB-0747-FY-S(P) Human Anti-CD44 Recombinant Antibody; scFv Fragment (HPAB-0747-FY-S(P)) ELISA Human scFv
HPAB-1055-FY-S(P) Mouse Anti-CD44 Recombinant Antibody; scFv Fragment (HPAB-1055-FY-S(P)) IHC, Inhib, FC Mouse scFv

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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