This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-EpCAM FAB to GM-CSF. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the EpCAM as well as the biological activity of GM-CSF. This fusion protein was directed against EpCAM and induced tumor cell lysis in vitro, which was dependent on the presence of the cytokine. Thus, GM-CSF activated PBMCs to lyse tumor cells, while IL-2 redirected lysis by T cells. This immunocytokine was designed for treating solid tumor.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1093z | Mouse Anti-EPCAM Recombinant Antibody (clone 41D5) | WB, FC, IHC, IP, FuncS | Mouse IgG1, κ |
HPAB-0163CQ | Human Anti-EPCAM Recombinant Antibody (clone HuMAB UBS-54) | ELISA, FC, FuncS | Human IgG1 |
HPAB-2216LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2216LY) | ELISA | Human IgG |
HPAB-2217LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2217LY) | ELISA | Human IgG |
HPAB-2218LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2218LY) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-235CL | Human Anti-Human EPCAM Recombinant Antibody (3622W94) | Cyt, FC | Antibody |
TAB-362MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) | Confocal, ELISA | Humanized antibody |
TAB-374MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8B) | FC, ELISA | Humanized antibody |
TAB-375MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8C) | FC, ELISA | Humanized antibody |
TAB-376MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h2D11B) | FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-356MZ | Anti-Human EPCAM Recombinant Antibody (3-171) | Cyt, ELISA, FC, WB | Human antibody |
TAB-357MZ | Anti-Human EPCAM Recombinant Antibody (7-F17) | ELISA | Human antibody |
TAB-358MZ | Anti-Human EPCAM Recombinant Antibody (12-C15) | ELISA | Human antibody |
TAB-359MZ | Anti-Human EPCAM Recombinant Antibody (16-G5) | ELISA | Human antibody |
TAB-360MZ | Anti-Human EPCAM Recombinant Antibody (17-C20) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-363MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-363MZ-S(P)) | Confocal, ELISA | Mouse scFv |
TAB-364MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-364MZ-S(P)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse scFv |
TAB-365MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-365MZ-S(P)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse scFv |
TAB-366MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-366MZ-S(P)) | ELISA, WB, IHC | Mouse scFv |
TAB-367MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-367MZ-S(P)) | ELISA, WB, IHC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0129CQ-F(E) | Human Anti-EPCAM Recombinant Antibody (clone 17-1A); Fab Fragment | ELISA, IHC, FC | Chimeric (mouse/human) Fab |
FAMAB-0130CQ-F(E) | Human Anti-EPCAM Recombinant Antibody (clone 323/A3); Fab Fragment | ELISA, IHC, FC | Chimeric (mouse/human) Fab |
FAMAB-0131CQ-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161); Fab Fragment | ELISA, IHC, FC | Mouse Fab |
HPAB-2216LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) | ELISA | Human Fab |
HPAB-2217LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2217LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2232LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2232LY-S(P)) | ELISA | Human scFv |
HPAB-AP343-YC-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-AP343-YC-S(P)) | ELISA, WB | Humanized scFv |
HPAB-0428-FY-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-0428-FY-S(P)) | ELISA | Mouse scFv |
HPAB-1316WJ-S(P) | Human Anti-EPCAM Recombinant Antibody (clone LD9); scFv Fragment | ELISA | Humanized scFv |
HPAB-2051-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone 02-237); scFv Fragment | FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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