Recombinant Humanized monoclonal antibody expressed in CHO binding to Human EPCAM. 3622W94 is a humanized murine monoclonal antibody (MoAb) against the 17-1A antigen, with potential adjuvant therapeutic properties in colorectal cancer.
Figure 1 ADCC activity of five clinically tested anti-EpCAM monoclonal antibodies.
ADCC was determined by dose response analysis as shown for 2 out of 5 human PBMC donors tested.
Münz, M., Murr, A., Kvesic, M., Rau, D., Mangold, S., Pflanz, S., ... & Rüttinger, D. (2010). Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies. Cancer cell international, 10(1), 44.
Figure 2 Mapping of the binding domain of adecatumumab to exon 5 of human EpCAM.
FACS histograms showing the binding of adecatumumab to 293 cells expressing the EpCAM constructs.
Münz, M., Murr, A., Kvesic, M., Rau, D., Mangold, S., Pflanz, S., ... & Rüttinger, D. (2010). Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies. Cancer cell international, 10(1), 44.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1093z | Mouse Anti-EPCAM Recombinant Antibody (clone 41D5) | WB, FC, IHC, IP, FuncS | Mouse IgG1, κ |
MOB-074LC | Human Anti-EPCAM Recombinant Antibody (clone ING-1) | ELISA, FuncS | Humanized IgG1, κ |
FAMAB-0095YC | Mouse Anti-EPCAM Recombinant Antibody (clone MOC31) | ELISA | Mouse IgG1, κ |
HPAB-2216LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2216LY) | ELISA | Human IgG |
HPAB-2217LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2217LY) | ELISA | Human IgG |
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(Creative Biolabs Cat# TAB-235CL, RRID: AB_3111892)
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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