Does this antibody distinguish FOLR1 from other folate receptors?

This Recombinant Human Antibody is specific for FOLR1 (Folate Receptor Alpha). While members of the folate receptor family are similar, this antibody has been validated to bind specifically to Human FOLR1, which is often overexpressed in certain cancers like ovarian carcinoma.

What are the recommended storage conditions?

The antibody should be stored at +4°C for short-term use (1-2 weeks). For long-term storage, aliquot and store at -20°C to prevent freeze/thaw cycles. It is supplied in PBS without preservatives, so sterile handling is recommended to maintain product integrity.

Human Anti-FOLR1 Recombinant Antibody (HPAB-0121-CN)

CAT#: HPAB-0121-CN

This product is a recombinant human antibody that recognizes FOLR1. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HeLa

Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1

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Specifications

Host Species
Human

Derivation
Humanized

Type
Humanized IgG

Specificity
Human FOLR1

Species Reactivity
Human

Applications
ELISA, FC, IHC, WB

Related Disease
Cancer

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Folate Receptor 1 (Adult); Ovarian Tumor-Associated Antigen MOv18; Adult Folate-Binding Protein; Folate Receptor, Adult; KB Cells FBP; FR-Alpha; FOLR; FBP; Folate Binding Protein; Folate Receptor; 1

Gene ID
2348

UniProt ID
P15328

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Breast cancer biomarkers at key points during disease progression

Specific Folate Receptor Binding

We used this human recombinant antibody to detect FOLR1 in ovarian cancer cell lines using Flow Cytometry. It showed high specificity for the folate receptor alpha, distinguishing it from other isoforms. It is a valuable reagent for our studies on folate transport and tumor markers.

Validated for Multiple Applications

We tested this antibody in ELISA, Western Blot, and Immunohistochemistry. It performed consistently across all applications, recognizing the human FOLR1 protein. The antibody is useful for researching the role of folate receptors in neurodegeneration and cellular uptake mechanisms.

Q&As

Does this antibody distinguish FOLR1 from other folate receptors?

A: This Recombinant Human Antibody is specific for FOLR1 (Folate Receptor Alpha). While members of the folate receptor family are similar, this antibody has been validated to bind specifically to Human FOLR1, which is often overexpressed in certain cancers like ovarian carcinoma.
What are the recommended storage conditions?

A: The antibody should be stored at +4°C for short-term use (1-2 weeks). For long-term storage, aliquot and store at -20°C to prevent freeze/thaw cycles. It is supplied in PBS without preservatives, so sterile handling is recommended to maintain product integrity.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# HPAB-0121-CN, RRID: AB_3713775)

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0121-CN.pdf

MSDS

MSDS - HPAB-0121-CN.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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