Human Anti-APP Recombinant Antibody (clone hu5E3); Fab Fragment (CAT#: HPAB-0105-YJ-F(E))
This product is a recombinant humanized Fab that recognizes human APP. It may function in treating and/or preventing amyloid-beta associated diseases such as Alzheimer's disease.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/60_E2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/60_E2_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/61_E2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/61_E2_1_blue_red_green.jpg
Figure 4 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/157/2073_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/157/2073_B_7_5.jpg
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human APP
- Species Reactivity
- Human
- Clone
- hu5E3
- Applications
- ELISA, WB
- Related Disease
- Alzheimer's disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma; Amyloid-beta precursor protein; Amyloid-beta A4 protein; Alzheimer disease amyloid protein; Amyloid beta (A4) precursor protein; Amyloid beta A4 protein; Amyloid precursor protein; Beta-amyloid peptide; Beta-amyloid peptide(1-40); Beta-amyloid peptide(1-42); Beta-amyloid precursor protein; Cerebral vascular amyloid peptide; Peptidase nexin-II; Protease nexin-II; Testicular tissue protein Li 2
- Gene ID
- 351
- UniProt ID
- P05067
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone hu5E3"
See other products for "APP"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody Products
Human Antibody Products
Single Domain Antibody Products
Chimeric Antibody Products
Humanized Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
Epitope-Specific Antibody Products
Neuroscience Antibody Products
Fab Antibody Products
IgG Antibody Products
ADCC Enhanced Antibody Products
IgM Antibody Products
ScFv Antibody Products
Antibody Magnetic Beads
Non-Human Primate (NHP) Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0010CL | Anti-Human APP Recombinant Antibody | ELISA, Block, FuncS, ELISA | |
| TAB-252CQ-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-252CQ-S(P)) | ELISA | Mouse scFv |
| TAB-255CQ-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-255CQ-S(P)) | ELISA | Mouse scFv |
| TAB-0764CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0764CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0765CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0765CLV-S(P)) | ELISA | Mouse scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0105-YJ-F(E). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, IHC, FC, Cyt, ELISA
Application: Neut, ELISA, Inhib, ICC, WB
-1.jpg)
Application: IB, ELISA, FC, FuncS
Application: ELISA, WB, Neut, Funcs, IHC, Inhib
Application: WB, ELISA, Neut, FuncS
Application: FC, IHC-Fr, IP, ELISA, Block
Application: WB, IHC-Fr, IHC-P, ICC, IF
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
