Human Anti-CD70 Recombinant Antibody (clone h1F6-HELA); scFv Fragment (CAT#: HPAB-AP587-YC-S(P))
Provided are recombinant anti-CD70 antibodies, that exert a cytotoxic, cytostatic or immunomodulatory on CD70 expressing cells. The antibody could be used for the prophylaxis or treatment of CD70-expressing cancers and immunological disorders where CD70-expressing cells are present.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
Figure 3 RNA cell line category: Cell line enhanced (SiHa, THP-1, U-251 MG, U-266/70, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
Specifications
- Host Species
- Human
- Derivation
- Humanized (mouse/human)
- Type
- Humanized (mouse/human) scFv
- Specificity
- Human CD70
- Species Reactivity
- Human, Mouse
- Clone
- h1F6-HELA
- Applications
- FC, ADCC, CDC, FuncS
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD70 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD70 Antigen; CD27 Ligand; CD27LG; TNFSF7; CD27-L
- Gene ID
- 970
- UniProt ID
- P32970
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone h1F6-HELA"
See other products for "CD70"
Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products
Human Antibody Products
Neutralizing Antibody Products
Blocking Antibody Products
ScFv Antibody Products
Fab Antibody Products
ADCC Enhanced Antibody Products
IgG Antibody Products
Hexamer Antibody Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
ScFv-Fc Chimera Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-335LC | Human Anti-CD70 Recombinant Antibody (TAB-335LC) | ELISA | Humanized IgG1, κ |
| TAB-335LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-335LC-F(E)) | ELISA | Humanized Fab |
| TAB-342LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-342LC-F(E)) | FC | Humanized Fab |
| TAB-343LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-343LC-F(E)) | FC | Humanized Fab |
| TAB-344LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-344LC-F(E)) | FC | Humanized Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-AP587-YC-S(P). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IP, WB, IHC, IF, FuncS
-YJ-3.jpg)
Application: ELISA
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, FuncS
Application: ELISA, Neut
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
