CytoStream™ Rabbit Anti-CD80 Recombinant Antibody (VS13-YC176)

Name: CytoStream™ Rabbit Anti-CD80 Recombinant Antibody (VS13-YC176)
SKU: VS13-YC176
Rating: 5 (1 reviews)

CAT#: VS13-YC176

The CytoStream™ Rabbit Anti-CD80 Recombinant Antibody is specific for human CD80. CD80, encoding a co-stimulatory molecule, impacts pathways modulating immune responses and diseases through coreceptor activity, linked to conditions like glomerulosclerosis. The anti-CD80 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

Gene Expression

Normal Tissue Figure 1 Bone marrow

Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25368/56116_B_6_4.jpg

Normal Tissue Figure 2 Lymph node

Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25368/56076_A_9_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-266/70)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121594-CD80

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Specifications

Immunogen
Recombinant human B7-1 protein.

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human CD80

Species Reactivity
Human

Applications
FC, ELISA

Conjugate
NONE

Related Disease
Focal Segmental Glomerulosclerosis and Vaccinia

Product Property

Clonality
Monoclonal

Purification
Affinity Chromatography purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.

Preservative
0.02% Sodium azide

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Shipping with ice pack.

Applications

Application Notes
Flow cytometry (FC): 1/50-1/100
ELISA: 1/10000

Target

Alternative Names
CD80 Molecule; CD80 Antigen (CD28 Antigen Ligand 1, B7-1 Antigen); B-Lymphocyte Activation Antigen B7; CTLA-4 Counter-Receptor B7.1; Activation B7-1 Antigen; CD28LG1; CD28LG; LAB7; BB1;

Gene ID
941

UniProt ID
P33681

Long Name
CD80 Molecule

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Related Diseases

Rheumatoid Arthritis

Systemic Lupus Erythematosus

Allograft Rejection

Autoimmune Thyroid Disease

Graft-versus-Host Disease

Maturity Onset Diabetes of the Young

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS13-YC176.pdf

MSDS

MSDS - VS13-YC176.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Secondary Antibody

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