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    Recombinant Anti-CD80 Vesicular Antibody, EV Displayed (VS-0425-YC176)

    CAT#: VS-0425-YC176

    The Recombinant Anti-CD80 Vesicular Antibody, EV Displayed (VS-0425-YC176) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD80-expressed cells or tissues. The CD80 is a protein associated with immune signaling pathways, linked to diseases such as Focal Segmental Glomerulosclerosis.

    Gene Expression
    ❮
    Figure 1 Bone marrow Figure 2 Lymph node Figure 3 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-266/70)
    ❯

    Recombinant Antibody

    • Application
    • ELISA, FC, Cell-uptake
    • Product Type
    • Ab-Fc-EVs
    • Antibody Quantification (Ab/EV)
    • ~100 Ab/EV
    • Target
    • CD80
    • Host Animal
    • Mouse
    • Antibody Isotype
    • IgG
    • Species Reactivity
    • Human
    • Expression Cell
    • Mammalian cell

    Engineered EVs

    • EV-sorting domain
    • CD63
    • Fc-binding domain
    • Protein A
    • EV Size
    • 30~150 nm
    • Producing Cell
    • HEK293F
    • Isolation Method
    • Gradient centrifugation
    • Purification
    • qEV size exclusion chromatography
    • Concentration
    • 1 x 10¹⁰
    • Size
    • 1 mL
    • Buffer
    • PBS
    • Storage
    • Store at -80°C for 12 months

    Target

    • Full Name
    • CD80 molecule
    • Biological Process
    • Host-virus interaction
    • Molecular Function
    • Host cell receptor for virus entry, Receptor
    • Introduction
    • CD80 (CD80 Molecule) is a Protein Coding gene. Diseases associated with CD80 include Focal Segmental Glomerulosclerosis and Vaccinia. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include coreceptor activity. An important paralog of this gene is CD86.
    • Alternative Names
    • B7-1, B7.1, CD28LG, CD28LG1
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    Related Diseases

    Rheumatoid Arthritis Rheumatoid Arthritis
    Systemic Lupus Erythematosus Systemic Lupus Erythematosus
    Allograft Rejection Allograft Rejection
    Autoimmune Thyroid Disease Autoimmune Thyroid Disease
    Graft-versus-Host Disease Graft-versus-Host Disease
    Maturity Onset Diabetes of the Young Maturity Onset Diabetes of the Young

    Downloadable Resources

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    Datasheet

    Datasheet - VS-0425-YC176.pdf

    MSDS

    MSDS - VS-0425-YC176.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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