Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Liposome (VS-1024-FY263)

Name: Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Liposome (VS-1024-FY263)
SKU: VS-1024-FY263
Rating: 5 (1 reviews)

CAT#: VS-1024-FY263

This product targets cell surface glycoprotein 2 by binding to monoclonal antibodies, enable specific internalization. The binding of the antibodies allows these positively charged lipoplexes to be selectively taken up by cells expressing the corresponding antigen. Research indicates that the internalization of lipoplexes is influenced by their surface charge rather than the concentration of polymer conjugates. This specific internalization mechanism enhances the potential of lipoplexes in gene transfection, allowing for more efficient delivery of DNA into target cells.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg

Normal Tissue Figure 2 Thyroid gland

Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg

Normal Tissue Figure 3 Colon

Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM

❮

❯

Sub Cat	Product Name	Liposome Name	Datasheet
VS-1124-FY4455	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled PEGylated Liposome (VS-1124-FY4455)	PEGylated liposome
VS-1124-FY4456	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Triptolide-loaded Liposome (VS-1124-FY4456)	Triptolide-loaded liposome
VS-1124-FY4457	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Gd-SLs Liposome (VS-1124-FY4457)	Gd-SLs liposome
VS-1124-FY4458	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Phospholipid Liposome (VS-1124-FY4458)	Phospholipid liposome
VS-1124-FY4459	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Cationic Liposome (VS-1124-FY4459)	Cationic liposome
VS-1124-FY4460	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Adriamycin-encapsulated Liposome (VS-1124-FY4460)	Adriamycin-encapsulated liposome
VS-1124-FY4461	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Magnetofluorescent Liposome (VS-1124-FY4461)	Magnetofluorescent liposome
VS-1124-FY4462	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled pH-sensitive Liposome (VS-1124-FY4462)	pH-sensitive liposome
VS-1124-FY4463	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Phototoxic Liposome (VS-1124-FY4463)	Phototoxic liposome
VS-1124-FY4464	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Targeted Liposome (VS-1124-FY4464)	Targeted Liposome
VS-1124-FY4465	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Apt1-Liposome (VS-1124-FY4465)	Apt1-liposome
VS-1124-FY4466	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Thermosensitive Liposome (VS-1124-FY4466)	Thermosensitive liposome
VS-1124-FY4467	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Clodronate Liposome (VS-1124-FY4467)	Clodronate liposome
VS-1124-FY4468	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Galcer Liposome (VS-1124-FY4468)	Galcer liposome
VS-1124-FY4469	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled HBsAg-loaded Liposome (VS-1124-FY4469)	HBsAg-loaded liposome
VS-1124-FY4470	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled Phospholipid Liposome and Cationic Liposome (VS-1124-FY4470)	Phospholipid liposome and Cationic liposome
VS-1124-FY4471	Anti-EPCAM (clone 3-171) Recombinant Antibody Coupled ISMN Liposome (VS-1124-FY4471)	ISMN liposome

More Infomation

Specifications

Potential Clinical Applications
Lipoplexes target cell surface glycoprotein 2 by binding to monoclonal antibodies, achieving specific internalization.

Product Composition

Clone
3-171

Antibody Type
IgG1, kappa

Antibody Host
Human

Antibody Reactivity
Human

Antibody Description
This mouse monoclonal antibody is designed for immunohistochemistry (IHC) applications, specifically targeting Epithelial Specific Antigen, and demonstrates reactivity with human species. The immunogen used for the antibody was derived from neuraminidase-treated cells of a variant small cell lung carcinoma cell line known as GLS-1.

Product Property

Storage
See in the COA

Storage Shelf Time
See in the COA

Target Information

Target
EPCAM

Full Name
Epithelial Cell Adhesion Molecule

Sequence Similarities
Belongs to the EPCAM family.

Cellular Localization
Cell junction, Cell membrane, Membrane, Tight junction

Post Translation Modifications
Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.

Protein Refseq
NP_002345.2

Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for VS-1024-FY263. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

Datasheet - VS-1024-FY263.pdf

MSDS

MSDS - VS-1024-FY263.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "Clone 3-171"

CAT
Product Name

See other products for "EPCAM"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1093z	Mouse Anti-EPCAM Recombinant Antibody (clone 41D5)	WB, FC, IHC, IP, FuncS	Mouse IgG1, κ

CAT	Product Name	Application	Type
TAB-701	Anti-Human EpCAM/17-1A Recombinant Antibody (Edrecolomab)	ELISA, IP, FC, FuncS, IF, Neut	IgG2a - kappa

CAT	Product Name	Application	Type
TAB-213	Humanized Anti-EPCAM Recombinant Antibody (clone Tucotuzumab)	WB, Neut, ELISA, IF, IP, FuncS, FC	Humanized (from mouse) IgG1

CAT	Product Name	Application	Type
TAB-106	Anti-Human EPCAM Recombinant Antibody (Adecatumumab)	FC, IHC, FuncS, Inhib, Cyt	IgG1

CAT	Product Name	Application	Type
TAB-112-F(E)	Anti-Human EpCAM Recombinant Antibody Fab Fragment, 17-1A (Citatuzumab Bogatox)	Neut, ELISA, IF, IP, FuncS, FC, ICC	Fab - G1 - kappa

CAT	Product Name	Application	Type
AGTO-L013E	anti-EPCAM immunotoxin MOC31 (IgG)-PE	Cytotoxicity assay, Functional assay

CAT	Product Name	Application	Type
AGTO-L013D	anti-EPCAM immunotoxin MOC31 (IgG)-DT	Cytotoxicity assay, Functional assay

CAT	Product Name	Application	Type
AGTO-L013G	anti-EPCAM immunotoxin MOC31 (IgG)-Gel	Cytotoxicity assay, Functional assay

CAT	Product Name	Application	Type
AGTO-L013R	anti-EPCAM immunotoxin MOC31 (IgG)-RTA	Cytotoxicity assay, Functional assay

CAT	Product Name	Application	Type
AGTO-L013O	anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin	Cytotoxicity assay, Functional assay

CAT	Product Name	Application	Type
TAB-235CL	Human Anti-Human EPCAM Recombinant Antibody (3622W94)	Cyt, FC	Antibody

CAT	Product Name	Application	Type
TAB-0531CL	Anti-Human EPCAM Recombinant Antibody (HE2)	ELISA, Inhib

CAT	Product Name	Application	Type
TAB-0531CL-S(P)	Anti-Human EPCAM Recombinant Antibody scFv Fragment (HE2)	ELISA, Inhib

CAT	Product Name	Application	Type
TAB-0531CL-F(E)	Anti-Human EPCAM Recombinant Antibody Fab Fragment (HE2)	ELISA, Inhib

CAT	Product Name	Application	Type
TAB-356MZ	Anti-Human EPCAM Recombinant Antibody (3-171)	Cyt, ELISA, FC, WB	Human antibody

CAT	Product Name	Application	Type
TAB-357MZ	Anti-Human EPCAM Recombinant Antibody (7-F17)	ELISA	Human antibody

CAT	Product Name	Application	Type
TAB-358MZ	Anti-Human EPCAM Recombinant Antibody (12-C15)	ELISA	Human antibody

CAT	Product Name	Application	Type
TAB-359MZ	Anti-Human EPCAM Recombinant Antibody (16-G5)	ELISA	Human antibody

CAT	Product Name	Application	Type
TAB-363MZ	Mouse Anti-EPCAM Recombinant Antibody (TAB-363MZ)	ELISA, FuncS	Mouse IgG1, κ

CAT	Product Name	Application	Type
TAB-374MZ	Anti-Human EPCAM Recombinant Antibody (h12H8B)	FC, ELISA	Humanized antibody

CAT	Product Name	Application	Type
TAB-375MZ	Anti-Human EPCAM Recombinant Antibody (h12H8C)	FuncS, Inhib	Humanized antibody

CAT	Product Name	Application	Type
MOB-0093MZ	Recombinant Mouse Anti-Ep-CAM Antibody (clone IEA126)	IHC, WB, IF	Mouse antibody

CAT	Product Name	Application	Type
MOR-1163	Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB)	IHC-P, WB, ICC, ICC, IF	Rabbit IgG

CAT	Product Name	Application	Type
MOB-074LC	Human Anti-EPCAM Recombinant Antibody (clone ING-1)	ELISA, FuncS	Humanized IgG1, κ

CAT	Product Name	Application	Type
FAMAB-0095YC	Mouse Anti-EPCAM Recombinant Antibody (clone MOC31)	ELISA	Mouse IgG1, κ

CAT	Product Name	Application	Type
FAMAB-0095-YC-S(P)	Mouse Anti-EPCAM Recombinant Antibody (clone MOC31); scFv Fragment	ELISA	Mouse scFv

CAT	Product Name	Application	Type
FAMAB-0095-YC-F(E)	Mouse Anti-EPCAM Recombinant Antibody (clone MOC31); Fab Fragment	ELISA	Mouse Fab

CAT	Product Name	Application	Type
FAMAB-0129CQ	Human Anti-EPCAM Recombinant Antibody (clone 17-1A)	ELISA, IHC, FC	Chimeric (mouse/human) IgG

CAT	Product Name	Application	Type
FAMAB-0129CQ-F(E)	Human Anti-EPCAM Recombinant Antibody (clone 17-1A); Fab Fragment	ELISA, IHC, FC	Chimeric (mouse/human) Fab

CAT	Product Name	Application	Type
FAMAB-0130CQ-F(E)	Human Anti-EPCAM Recombinant Antibody (clone 323/A3); Fab Fragment	ELISA, IHC, FC	Chimeric (mouse/human) Fab

CAT	Product Name	Application	Type
FAMAB-0131CQ-F(E)	Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161); Fab Fragment	ELISA, IHC, FC	Mouse Fab

CAT	Product Name	Application	Type
FAMAB-0129CQ-S(P)	Mouse Anti-EPCAM Recombinant Antibody (clone 17-1A); scFv Fragment	ELISA, IHC, FC	Mouse scFv

CAT	Product Name	Application	Type
FAMAB-0130CQ-S(P)	Mouse Anti-EPCAM Recombinant Antibody (clone 323/A3); scFv Fragment	ELISA, IHC, FC	Mouse scFv

CAT	Product Name	Application	Type
FAMAB-0131CQ-S(P)	Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161); scFv Fragment	ELISA, IHC, FC	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0163CQ-F(E)	Human Anti-EPCAM Recombinant Antibody (clone HuMAB UBS-54); Fab Fragment	ELISA, FC, FuncS	Human Fab

CAT	Product Name	Application	Type
HPAB-0163CQ-S(P)	Human Anti-EPCAM Recombinant Antibody (clone HuMAB UBS-54); scFv Fragment	ELISA, FC, FuncS	Human scFv

CAT	Product Name	Application	Type
MRO-0538-CN	Mouse Anti-EPCAM Recombinant Antibody (clone 3-E1-E2)	WB, IF, IHC, FC	Mouse IgM

CAT	Product Name	Application	Type
AFC-TAB-106	Afuco™ Anti-EPCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-106)	ELISA, IP, FC, FuncS, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-213	Afuco™ Anti-EPCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-213)	Neut, ELISA, IF, IP, FuncS	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-701	Afuco™ Anti-EpCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-701)	ELISA, IP, FC, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
MHC-CN0031	APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer	FCM

CAT	Product Name	Application	Type
MHC-CN0032	PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer	FCM

CAT	Product Name	Application	Type
VS-0724-YC1517	AbPlus™ Anti-EPCAM Magnetic Beads (VS-0724-YC1517)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0924-YC37	Mouse Anti-EPCAM Recombinant Antibody (VS-0924-YC37) - Cancer Stem Cell Marker	IHC, WB	Mouse IgG1

CAT	Product Name	Application	Type
VS-0924-YC38	Rabbit Anti-EPCAM Antibody (VS-0924-YC38) - Cancer Stem Cell Marker	IHC, WB	Rabbit IgG

CAT	Product Name	Application	Type
VS-0125-FY18	Human Anti-EpCAM (clone 3-171) scFv-Fc Chimera	Cyt, ELISA, FC, WB	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0225-XY107	CytoStream™ Mouse Anti-EPCAM Recombinant Antibody (VS-0225-XY107)	FC	Mouse IgG2b, kappa

CAT	Product Name	Application	Type
VS-0325-XY773	Anti-EPCAM Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0425-YC210	Recombinant Anti-EPCAM Vesicular Antibody, EV Displayed (VS-0425-YC210)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY2307	Anti-Human EPCAM Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY2308	Anti-Mouse EPCAM Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-YC214	Recombinant Anti-EpCAM (Exon 2 x Exon 5) Biparatopic Antibody, Tandem scFv (Edrecolomab x Adecatumumab)	ELISA, FC	Tandem scFv

CAT	Product Name	Application	Type
VS-0525-XY2309	Anti-Canine EPCAM Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0825-YC114	SmartAb™ Recombinant Anti-EpCAM pH-dependent Antibody (Clone Edrecolomab)	ELISA, IP, FC IF, Neut	Mouse IgG2a kappa

CAT	Product Name	Application	Type
VS-1025-YC211	Anti-EpCAM Antibody Prodrug, Protease Activated (VS-1025-YC211)	ISZ, Cyt, FuncS

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Anti-CD248 Recombinant Antibody (Ontuxizumab) (CAT# TAB-773)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Anti-Human FAP Recombinant Antibody (TAB-211) (CAT# TAB-211)
Application: ELISA, IP, FC, FuncS, Neut, IF, WB

Anti-Human CD40L Recombinant Antibody (TAB-027) (CAT# TAB-027)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Anti-Human IL13 Recombinant Antibody (Tralokinumab) (CAT# TAB-218)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Human Anti-GPNMB Recombinant Antibody (clone Glembatumumab) (CAT# TAB-751)
Application: WB, IF, IP, Neut, FuncS, ELISA, FC

Anti-Human Nogo-A Recombinant Antibody (TAB-903) (CAT# TAB-903)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Anti-Human EGFR Recombinant Antibody (TAB-119) (CAT# TAB-119)
Application: FC, IP, ELISA, Neut, FuncS, IF, WB

Human Anti-PDCD1 Recombinant Antibody (TAB-H55) (CAT# TAB-H55)
Application: Inhib, Agonist

Anti-Human MUC5AC Recombinant Antibody (TAB-200) (CAT# TAB-200)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Anti-Human GPC3 Recombinant Antibody (Codrituzumab) (CAT# TAB-H14)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC

Anti-Human CD18 Recombinant Antibody F(ab')₂ Fragment (TAB-154-F(E)) (CAT# TAB-154-F(E))
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Anti-Human DKK1 Recombinant Antibody (BHQ880) (CAT# TAB-214CL)
Application: IHC, ELISA, IB

Anti-Human GD2 Recombinant Antibody (hu14.18K322A) (CAT# TAB-304CL)
Application: FC, FuncS

Mouse Anti-GD2 Recombinant Antibody (clone 3F8) (CAT# PABL-101)
Application: FC, ELISA, FuncS

Human Anti-HIV-1 Env Recombinant Antibody (clone PGDM1400) (CAT# PABL-151)
Application: Neut, FuncS

Recombinant Mouse Anti-Staphylococcal enterotoxin B Antibody (PABL-706) (CAT# PABL-706)
Application: WB, IF, FuncS

Human Anti-IL13 Recombinant Antibody (clone CNTO607) (CAT# PABW-170)
Application: ELISA, WB, Neut

Anti-LPA Recombinant Antibody (LT3015 [B7(LT3000, Lpathomab)]) (CAT# TAB-0340CL)
Application: ELISA, SPR, Inhib, FuncS

Anti-Human TIM3 Recombinant Antibody (TSR-022) (CAT# TAB-0366CL)
Application: FC, FuncS

Anti-Human LAG3 Recombinant Antibody (TSR-033) (CAT# TAB-0367CL)
Application: FC, FuncS, Block

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.