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    AbPlus™ Anti-IL2RA Magnetic Beads (2R12)

    CAT#: VS-0424-XY150

    The AbPlus Anti-IL2RA Magnetic Beads (2R12) is an innovative affinity resin which is bound with anti-IL2RA specific antibody (2R12). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IL2RA protein under native and denaturing conditions.

    Gene Expression
    ❮
    Figure 1 Lymph node Figure 2 Tonsil Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
    ❯

    Specifications

    • Applications
    • Immunoprecipitation, Protein Purification
    • Matrix
    • Magrose bead (> 50 μmol/mL gel)
    • Bead Ligand
    • Anti-IL2RA specific antibody (2R12)
    • Target
    • IL2RA
    • Immunogen
    • p55 alpha chain of the human IL-2 receptor
    • Target Species
    • Human
    • Antibody Clone
    • 2R12
    • Bead Capacity
    • 20-30 mg/mL binding antibody
    • Bead size
    • 10-37 μm
    • Stability
    • pH 2-14
    • Format
    • 20% Suspension
    • Buffer
    • PBS, pH 7.4, with 1% BSA
    • Preservative
    • 0.03% Proclin 300
    • Storage
    • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

    Applications

    • Application Notes
    • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

    Target

    • Introduction
    • The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
    • Alternative Names
    • IL2RA; interleukin 2 receptor; alpha; p55; CD25; IL2R; TCGFR; IDDM10; interleukin-2 receptor subunit alpha; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha
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    Datasheet

    Datasheet - VS-0424-XY150.pdf

    MSDS

    MSDS - VS-0424-XY150.pdf

    COA

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