Anti-human IL2RA Recombinant Antibody (48V54S) (TAB-648LC) (CAT#: TAB-648LC)
This antibody is a recombinant human antibody that recognizes Interleukin-2 receptor subunit alpha (IL2RA). The antibody was purified by affinity chromatography. It is capable of being used in research of multiple sclerosis. It has been detected by Enzyme-linked immunosorbent assay and other applications.
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Figure 1 Average proliferative responses of human PBMC to E.HAT Fab and four variants.
Heat inactivated Fab fragments from the E.HAT and four variant antibodies were cocultured with human PBMC for 6 days. Stimulation indexes were calculated for each donor at each concentration, and the results were averaged. Data is shown as average SI±sem.
Figure 2 The average stimulation index versus the percentage of donors responding with an SI>1.99.
Data for the 25 μL/mL concentration was selected, and was graphed versus the percent of donors whose proliferative response reached a value of 1.99 or greater.
Figure 3 The average stimulation index for all tested variants from donors who responded with an SI greater than 1.99 to the E.HAT Fab.
The proliferative responses from all donors whose responses were greater than 1.99 at the 25 μg/ml concentration were averaged. Data is shown as average SI+sem.
FuncS
Figure 1 shows average proliferative responses of human PBMC to E.HAT Fab and four variants.
Heat inactivated Fab fragments from the E.HAT and four variant antibodies were cocultured with human PBMC for 6 days. Stimulation indexes were calculated for each donor at each concentration, and the results were averaged. Data is shown as average SI + sem.
FuncS
Figure 2 shows the average stimulation index versus the percentage of donors responding with an SI > 1.99. Data for the 25 ug/ml concentration was selected, and was graphed versus the percent of donors whose proliferative response reached a value of 1.99 or greater.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- 48V54S
- Applications
- FuncS
- Related Disease
- Multiple sclerosis
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
- Alternative Names
- IL2RA; interleukin 2 receptor, alpha; p55; CD25; IL2R; TCGFR; IDDM10; interleukin-2 receptor subunit alpha; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha
- Gene ID
- 3559
- UniProt ID
- P01589
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1094z | Mouse Anti-IL2RA Recombinant Antibody (clone 18C9) | WB, ELISA, IF, IHC, FuncS | Mouse IgG1, κ |
| PABZ-020 | Human Anti-IL2RA Recombinant Antibody (clone CHI621) | Block | Chimeric (mouse/human) IgG |
| PABZ-082 | Human Anti-IL2RA Recombinant Antibody (clone SDZ CHI621) | Block | Chimeric (mouse/human) IgG |
| MOB-0351MZ | Recombinant Mouse Anti-Human IL2RA Antibody (clone BCT-2) | ELISA | Mouse antibody |
| VS3-WK1278 | Rat Anti-IL2RA Recombinant Antibody (clone PC-61.5.3) | IF, FC | Rat IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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