Rabbit Anti-IL2RA Antibody (VS-0924-YC47) - Cancer Stem Cell Marker (CAT#: VS-0924-YC47)
This product is an anti-IL2RA antibody (VS-0924-YC47). It specifically targets the human IL2RA protein, which is a marker for cancer stem cells (CSCs). The antibody is suitable for detecting IL2RA in CSC tissues or cells using Immunohistochemistry, at dilutions ranging from 1:1000 to 1:2500.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
Figure 2 Tonsil
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL2RA
- Species Reactivity
- Human
- Applications
- IHC
- Related Disease
- Immunodeficiency 41 With Lymphoproliferation And Autoimmunity and Type 1 Diabetes Mellitus 10
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity purified using the PrEST antigen as affinity ligand
- Concentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.2, with 40% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/1000-1/2500
Target
- Alternative Names
- p55; CD25; IL2R; IMD41; TCGFR; IDDM10
- Gene ID
- 3559
- UniProt ID
- P01589
- Long Name
- Interleukin 2 receptor, alpha
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn70, Asn89, Thr218, Thr224, Thr229, and Thr237 (NX_P01589 [NX_P01589-1])
Modification sites at PhosphoSitePlus (P01589)
Glycosylation from GlyGen (P01589) 6 sites
- Protein Refseq
- NP_001295171.1; NP_000408.1
- Function
- Receptor for interleukin-2.
The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
TREGs suppress the activation and expansion of autoreactive T-cells.
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Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
| IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
| IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
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