Anti-Human CD25 Recombinant Antibody (Basiliximab) (CAT#: TAB-004)
Recombinant monoclonal antibody to Human CD25. Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a chimeric CD25 monoclonal antibody of the IgG1 isotype. It acts as an antagonist at the interleukin-2(IL-2) binding site of the p55 subunit (Tac antigen) of the high affinity IL-2 receptor (CD25) on the surface of the activated T lymphocytes.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
Figure 2 Tonsil
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Chimeric (mouse/human)
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen
- Species Reactivity
- Human
- Applications
- Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
- Trade name
- simulect
- CAS
- 152923-56-3
- Generic Name
- Basiliximab
- Biological Half-Life
- 7.2 days
- ATC Code
- L04AC02
- DrugBank
- DB00074
- UNII
- 9927MT646M
- ChEMBL
- CHEMBL1201439
- MW
- 143,801.3 g/mol
- Related Disease
- Kidney transplant rejection, acute
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- Basiliximab;simulect;152923-56-3;SDZ CHII621;DB00074IL2RA;interleukin 2 receptor, alpha;IL2R;interleukin-2 receptor subunit alpha;CD25;p55;IL2-RA;IL-2-RA;TAC antigen;IL-2R subunit alpha;IL-2 receptor subunit alpha;TCGFR;IDDM10;
- Gene ID
- 3559
- UniProt ID
- P01589
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Basiliximab"
Afuco™ Anti-IL2RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-004)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human CD25. It is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a chimeric CD25 monoclonal antibody of the IgG1 isotype. It acts as an antagonist at the interleukin-2(IL-2) binding site of the p55 subunit (Tac antigen) of the high affinity IL-2 receptor (CD25) on the surface of the activated T lymphocytes.
DrugMonitor™ Anti-Basiliximab Antibody (VS-1224-YC163)Basiliximab is a recombinant chimeric (murine/human) monoclonal antibody functioning as an immunosuppressant by binding to and blocking the IL-2R alpha on activated T-lymphocytes. The DrugMonitor™ Anti-Basiliximab Antibody (VS-1224-YC163) is an anti-drug antibody (ADA) against Basiliximab. This drug-based antibody is raised in mice immunized with the Basiliximab. The anti-Basiliximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Basiliximab in samples.
See other products for "IL2RA"
Select a product category from the dropdown menu below to view related products.
Please select product type
Intrabody Products
Mouse Antibody Products
Immunotoxin Products
ScFv Antibody Products
Fab Antibody Products
Human Antibody Products
Humanized Antibody Products
Chimeric Antibody Products
Neutralizing Antibody Products
Blocking Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
Hexamer Antibody Products
Cancer Stem Cell Biomarker Specific Antibody Products
ScFv-Fc Chimera Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
| IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
| IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-004. Click the button above to contact us or submit your feedback about this product.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-004, RRID: AB_3111732)
Copy citation
Popular products with customers
Application: FC, Cyt, Stim, PP, Agonist
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, Inhib, FC
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, Inhib
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
