Anti-Human CD25 Recombinant Antibody (Basiliximab) (CAT#: TAB-004)

Recombinant monoclonal antibody to Human CD25. Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a chimeric CD25 monoclonal antibody of the IgG1 isotype. It acts as an antagonist at the interleukin-2(IL-2) binding site of the p55 subunit (Tac antigen) of the high affinity IL-2 receptor (CD25) on the surface of the activated T lymphocytes.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • IgG1 - kappa
  • Specificity
  • Tested positive against native human antigen
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
  • Trade name
  • simulect
  • CAS
  • 152923-56-3
  • Generic Name
  • Basiliximab
  • Biological Half-Life
  • 7.2 days
  • ATC Code
  • L04AC02
  • DrugBank
  • DB00074
  • UNII
  • 9927MT646M
  • ChEMBL
  • CHEMBL1201439
  • MW
  • 143,801.3 g/mol
  • Related Disease
  • Kidney transplant rejection, acute

Product Property

  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Target

  • Alternative Names
  • Basiliximab;simulect;152923-56-3;SDZ CHII621;DB00074IL2RA;interleukin 2 receptor, alpha;IL2R;interleukin-2 receptor subunit alpha;CD25;p55;IL2-RA;IL-2-RA;TAC antigen;IL-2R subunit alpha;IL-2 receptor subunit alpha;TCGFR;IDDM10;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Basiliximab"

Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Basiliximab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human CD25. Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a chimeric CD25 monoclonal antibody of the IgG1 isotype. It acts as an antagonist at the interleukin-2(IL-2) binding site of the p55 subunit (Tac antigen) of the high affinity IL-2 receptor (CD25) on the surface of the activated T lymphocytes.

See other products for "IL2RA"

Intrabody

CAT Product Name Application Type
IAB-B073(A) Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] IF, ELISA, FuncS scFv-(D-Arg)9
IAB-B073(G) Recombinant Anti-human IL2RA Intrabody [+36 GFP] IF, FC, WB, FuncS scFv-(+36GFP)
IAB-B073(T) Recombinant Anti-human IL2RA Intrabody [Tat] WB, CO-IP, FuncS scFv-Tat

Immunotoxin

CAT Product Name Application Type
AGTO-L027D anti-IL2RA immunotoxin RFT5 (scFv)-DT Cytotoxicity assay, Functional assay
AGTO-L027R anti-IL2RA immunotoxin RFT5 (scFv)-RTA Cytotoxicity assay, Functional assay
AGTO-L028E anti-IL2RA immunotoxin RFT5 (IgG)-PE Cytotoxicity assay, Functional assay
AGTO-L028D anti-IL2RA immunotoxin RFT5 (IgG)-DT Cytotoxicity assay, Functional assay
AGTO-L028R anti-IL2RA immunotoxin RFT5 (IgG)-RTA Cytotoxicity assay, Functional assay

Chimeric Antibody

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1350CQ Mouse Anti-IL2RA Recombinant Antibody (clone 2R12) Block, FC, ICC, IF, IHC, IP, WB Mouse IgG1
NEUT-1356CQ Rat Anti-Il2ra Recombinant Antibody (VMC199) FC, IP, IHC, Block, Depletion Rat IgG1, λ
NEUT-1357CQ Rat Anti-Il2ra Recombinant Antibody (clone 3C7) FC, IP, Inhib Rat IgG2b, κ
NEUT-1358CQ Rat Anti-Il2ra Recombinant Antibody (clone mAb0817) Block, Depletion Rat IgG1
NEUT-1359CQ Rat Anti-Il2ra Recombinant Antibody (clone mAb0845) Block, FC, IHC-Fr, IP Rat IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1808 Rabbit Anti-IL2RA Recombinant Antibody (clone DS1808AB) IHC, ICC, IP Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-004 Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Basiliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-023 Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Daclizumab), ADCC Enhanced ELISA, Neut, IF, IP, FC, FuncS ADCC enhanced antibody
AFC-TAB-155 Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Inolimomab), ADCC Enhanced IP, IF, FuncS, FC, Neut, ELISA ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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