Recombinant Anti-human IL2RA Intrabody [Tat]
CAT#: IAB-B073(T)
Recombinant anti-IL2RA intrabody in fusion with HIV Tat works within cells to bind human IL2RA, expressed in E. coli cells.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
❮
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Specifications
- Immunogen
- human interleukin 2 receptor, alpha
- Host Species
- mouse
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- human
- Applications
- Antibody assay: Western blot; Coimmunopricipation; Functional studies
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| TAB-155 | Anti-Human CD25 Recombinant Antibody (TAB-155) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
| TAB-641LC | Anti-human IL2RA Recombinant Antibody (TAB-641LC) | ELISA | |
| TAB-641LC-S(P) | Anti-human IL2RA scFv Fragment (TAB-641LC-S(P)) | ELISA | |
| TAB-641LC-F(E) | Anti-human IL2RA Fab Fragment (TAB-641LC-F(E)) | ELISA | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| AGTO-L027R | anti-IL2RA immunotoxin RFT5 (scFv)-RTA | Cytotoxicity assay, Functional assay | |
| AGTO-L028E | anti-IL2RA immunotoxin RFT5 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L028D | anti-IL2RA immunotoxin RFT5 (IgG)-DT | Cytotoxicity assay, Functional assay | |
| AGTO-L028R | anti-IL2RA immunotoxin RFT5 (IgG)-RTA | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-608 | Human Anti-IL2RA Recombinant Antibody (clone RTF5); Fab Fragment | WB, FuncS | Chimeric (mouse/human) Fab |
| FAMAB-0197CQ-F(E) | Mouse Anti-IL2RA Recombinant Antibody (clone 2C8); Fab Fragment | ELISA, WB, FC | Mouse Fab |
| HPAB-M0454-YC-F(E) | Mouse Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-M0454-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-2113-FY-F(E) | Mouse Anti-IL2RA Recombinant Antibody (clone MAK179); Fab Fragment | Inhib | Mouse Fab |
| HPAB-1536WJ-F(E) | Rat Anti-IL2RA Recombinant Antibody; Fab Fragment (clone YTH 906.9.21) | ELISA, WB | Rat Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-642LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-642LC-F(E)) | ELISA, FC | Human Fab |
| TAB-643LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-643LC-F(E)) | ELISA, FC | Human Fab |
| TAB-644LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-644LC-F(E)) | ELISA, FC | Human Fab |
| TAB-645LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-645LC-F(E)) | ELISA, FC | Human Fab |
| PABX-029-F (E) | Recombinant Human Anti-CD25 Antibody Fab Fragment (Daclizumab) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-646LC-F(E) | Anti-human IL2RA Fab Fragment (48M54S) | ELISA, FC | Humanized antibody |
| TAB-647LC-F(E) | Anti-human IL2RA Fab Fragment (48M51L) | ELISA, FC | Humanized antibody |
| TAB-648LC-F(E) | Anti-human IL2RA Fab Fragment (48V54S) | ELISA, FC | Humanized antibody |
| TAB-649LC-F(E) | Anti-human IL2RA Fab Fragment (Dmab) | FC | Humanized antibody |
| TAB-650LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-650LC-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1344CQ | Mouse Anti-IL2RA Recombinant Antibody (clone B-B10) | FC, Neut, WB, IF | Mouse IgG1, κ |
| NEUT-1345CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL017) | Neut, WB, IHC | Mouse IgG1 |
| NEUT-1346CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL242) | ELISA, FC, Neut | Mouse IgG1, κ |
| NEUT-1348CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL726) | WB, IHC, ICC, Neut | Mouse IgG1 |
| NEUT-1349CQ | Mouse Anti-IL2RA Recombinant Antibody (NEUT-1349CQ) | IHC, Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1350CQ | Mouse Anti-IL2RA Recombinant Antibody (NEUT-1350CQ) | Block, FC, ICC, IF, IHC, IP, WB | Mouse IgG1 |
| NEUT-1356CQ | Rat Anti-Il2ra Recombinant Antibody (VMC199) | FC, IP, IHC, Block, Depletion | Rat IgG1, λ |
| NEUT-1357CQ | Rat Anti-Il2ra Recombinant Antibody (clone 3C7) | FC, IP, Inhib | Rat IgG2b, κ |
| NEUT-1358CQ | Rat Anti-Il2ra Recombinant Antibody (NEUT-1358CQ) | Block, Depletion | Rat IgG1 |
| NEUT-1359CQ | Rat Anti-Il2ra Recombinant Antibody (NEUT-1359CQ) | Block, FC, IHC-Fr, IP | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1808 | Rabbit Anti-IL2RA Recombinant Antibody (clone DS1808AB) | IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0197CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 2C8) | ELISA, WB, FC | Mouse IgG1, κ |
| FAMAB-0198CQ | Human Anti-IL2RA Recombinant Antibody (clone 4C1) | ELISA, WB, FC | Chimeric (mouse/human) IgG1, κ |
| FAMAB-0199CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 4F8) | ELISA, WB, FC | Mouse IgG2a, κ |
| HPAB-0060-FY | Human Anti-IL2RA Recombinant Antibody (HPAB-0060-FY) | ELISA, PD | Humanized IgG1, κ |
| HPAB-0197-FY | Mouse Anti-IL2RA Recombinant Antibody (clone WuTac) | FC, DB, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0197CQ-S(P) | Mouse Anti-IL2RA Recombinant Antibody (clone 2C8); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| FAMAB-0198CQ-S(P) | Mouse Anti-IL2RA Recombinant Antibody (clone 4C1); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| FAMAB-0199CQ-S(P) | Mouse Anti-IL2RA Recombinant Antibody (clone 4F8); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| HPAB-0060-FY-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0060-FY-S(P)) | ELISA | Humanized scFv |
| HPAB-0197-FY-S(P) | Mouse Anti-IL2RA Recombinant Antibody (clone WuTac); scFv Fragment | FC, DB, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-004 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-004) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-023 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-023) | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
| AFC-TAB-155 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-155) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY150 | AbPlus™ Anti-IL2RA Magnetic Beads (2R12) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC133 | Human Anti-IL2RA Recombinant Antibody Hexamer (VS-0924-YC133), CDC Enhanced | CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC47 | Rabbit Anti-IL2RA Antibody (VS-0924-YC47) - Cancer Stem Cell Marker | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY44 | Human Anti-IL2RA (clone MAK179) scFv-Fc Chimera | Inhib | Human IgG1, scFv-Fc |
| VS-0425-FY42 | Mouse Anti-IL2RA (clone mAb1) scFv-Fc Chimera | ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY135 | CytoStream™ Mouse Anti-IL2RA Recombinant Antibody (clone BC96) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC386 | Recombinant Anti-IL2RA Vesicular Antibody, EV Displayed (VS-0425-YC386) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3520 | Anti-IL2RA Immunohistochemistry Kit | IHC | |
| VS-0525-XY3521 | Anti-Mouse IL2RA Immunohistochemistry Kit | IHC | |
| VS-0525-XY3522 | Anti-Rat IL2RA Immunohistochemistry Kit | IHC |
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