Anti-human IL2RA Recombinant Antibody (48M54S) (TAB-646LC) (CAT#: TAB-646LC)

Figure 1 Average proliferative responses of human PBMC to E.HAT Fab and four variants.

Heat inactivated Fab fragments from the E.HAT and four variant antibodies were cocultured with human PBMC for 6 days. Stimulation indexes were calculated for each donor at each concentration, and the results were averaged. Data is shown as average SI±sem.

Figure 2 The average stimulation index versus the percentage of donors responding with an SI>1.99.

Data for the 25 μL/mL concentration was selected, and was graphed versus the percent of donors whose proliferative response reached a value of 1.99 or greater.

Figure 3 The average stimulation index for all tested variants from donors who responded with an SI greater than 1.99 to the E.HAT Fab.

The proliferative responses from all donors whose responses were greater than 1.99 at the 25 μg/ml concentration were averaged. Data is shown as average SI+sem.

Figure 4 The average stimulation index versus the percentage of donors responding with an SI greater than 1.99.

Data for the 25 μg/ml concentration was selected, and was graphed versus the percent of donors whose proliferative response reached a value of 1.99 or greater.

Figure 1 shows average proliferative responses of human PBMC to E.HAT Fab and four variants.

Heat inactivated Fab fragments from the E.HAT and four variant antibodies were cocultured with human PBMC for 6 days. Stimulation indexes were calculated for each donor at each concentration, and the results were averaged. Data is shown as average SI + sem.

Figure 2 shows the average stimulation index versus the percentage of donors responding with an SI > 1.99. Data for the 25 ug/ml concentration was selected, and was graphed versus the percent of donors whose proliferative response reached a value of 1.99 or greater.