Human Anti-IL2RA (clone MAK179) scFv-Fc Chimera (CAT#: VS-0125-FY44)
Anti-CD25 NP scFv-Fc is a novel monoclonal antibody specifically targeting the CD25 molecule, featuring high specificity and affinity. This makes it a powerful tool for diagnosis and treatment in Adult T-cell Leukemia Lymphoma (ATLL) and various immune disorders. This antibody not only aids researchers in gaining a better understanding of the pathogenesis of ATLL but also provides new therapeutic strategies for clinical use, potentially improving patient survival rates and quality of life. Moreover, the application prospects of anti-CD25 NP scFv-Fc are broad, holding promise for the development of innovative immunotherapy methods and contributing to the advancement of precision medicine.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_8_8.jpg
Figure 2 Tonsil
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54622/137874_A_4_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134460-IL2RA
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human
- Clone
- MAK179
- Applications
- Inhibition
- Related Disease
- Adult T cell leukemia lymphoma (ATLL)
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- It can potentially serve as an effective tool for the diagnosis and treatment of adult T-cell leukemia/lymphoma (ATLL) and a range of autoimmune diseases.
Target
- Alternative Names
- Interleukin 2 Receptor Subunit Alpha
- Gene ID
- 3559
- UniProt ID
- P01589
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn70, Asn89, Thr218, Thr224, Thr229, and Thr237
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 6 sites
- Protein Refseq
- NP_001295171.1; NP_000408.1
- Function
- Receptor for interleukin-2.
The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
TREGs suppress the activation and expansion of autoreactive T-cells.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone MAK179"
See other products for "IL2RA"
Select a product category from the dropdown menu below to view related products.
Please select product type
Intrabody Products
Chimeric Antibody Products
Mouse Antibody Products
Immunotoxin Products
ScFv Antibody Products
Human Antibody Products
Humanized Antibody Products
IgG Antibody Products
Neutralizing Antibody Products
Blocking Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
Hexamer Antibody Products
Cancer Stem Cell Biomarker Specific Antibody Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
ScFv-Fc Chimera Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
| IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
| IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0125-FY44. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, Inhib, ICC, WB
-YJ-3.jpg)
Application: ELISA
Application: Neut, Inhib, FC, ELISA
Application: ELISA, FC, WB, Block
Application: ELISA, IHC, FC, WB, IF, IA
Application: ELISA
Application: SPR, Inhib, FuncS
-2.png)
Application: WB, ELISA, FuncS
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
