Human Anti-IL2RA (clone MAK179) scFv-Fc Chimera (CAT#: VS-0125-FY44)

Anti-CD25 NP scFv-Fc is a novel monoclonal antibody specifically targeting the CD25 molecule, featuring high specificity and affinity. This makes it a powerful tool for diagnosis and treatment in Adult T-cell Leukemia Lymphoma (ATLL) and various immune disorders. This antibody not only aids researchers in gaining a better understanding of the pathogenesis of ATLL but also provides new therapeutic strategies for clinical use, potentially improving patient survival rates and quality of life. Moreover, the application prospects of anti-CD25 NP scFv-Fc are broad, holding promise for the development of innovative immunotherapy methods and contributing to the advancement of precision medicine.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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Other Requirements:
We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Species Reactivity
  • Human
  • Clone
  • MAK179
  • Applications
  • Inhibition
  • Related Disease
  • Adult T cell leukemia lymphoma (ATLL)

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Stabilizer
  • No Stabilizers
  • Sterility
  • 0.2 μM filtered
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • It can potentially serve as an effective tool for the diagnosis and treatment of adult T-cell leukemia/lymphoma (ATLL) and a range of autoimmune diseases.

Target

  • Alternative Names
  • Interleukin 2 Receptor Subunit Alpha
  • Cellular Localization
  • Membrane
  • Post Translation Modifications
  • Glycosylation at Asn70, Asn89, Thr218, Thr224, Thr229, and Thr237
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyGen 6 sites
  • Function
  • Receptor for interleukin-2.
    The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
    TREGs suppress the activation and expansion of autoreactive T-cells.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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MOB-1094z Mouse Anti-IL2RA Recombinant Antibody (clone 18C9) WB, ELISA, IF, IHC, FuncS Mouse IgG1, κ
FAMAB-0197CQ Mouse Anti-IL2RA Recombinant Antibody (clone 2C8) ELISA, WB, FC Mouse IgG1, κ
FAMAB-0198CQ Human Anti-IL2RA Recombinant Antibody (clone 4C1) ELISA, WB, FC Chimeric (mouse/human) IgG1, κ
FAMAB-0199CQ Mouse Anti-IL2RA Recombinant Antibody (clone 4F8) ELISA, WB, FC Mouse IgG2a, κ
FAMAB-0200CQ Human Anti-IL2RA Recombinant Antibody (clone huD1) ELISA, FC, Block Humanized IgG1, κ

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