Human Anti-MUC1 Recombinant Antibody (clone E29) (CAT#: FAMAB-1222CQ)

This product is a recombinant human antibody that recognizes MUC1. The antibody was purified by affinity chromatography. It can be used in WB, IHC.


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IHC

Figure 1 APAAP staining of normal gastric mucosa with antibody E29, showing strong labelling of gastricparietal cells.

Figure 1 APAAP staining of normal gastric mucosa with antibody E29, showing strong labelling of gastricparietal cells.

In the higher power view the intracanalicular localisation of the antigen is seen (see arrowed cell).

Cordell, J., Richardson, T. C., Pulford, K. A., Ghosh, A. K., Gatter, K. C., Heyderman, E., & Mason, D. Y. (1985). Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. British journal of cancer, 52(3), 347-354.

IHC

Figure 2 APAAP staining of pancreas with antibody E29 shows strong labelling of exocrine glandularelements but no reactivity of islets of Langerhans (IL).

Figure 2 APAAP staining of pancreas with antibody E29 shows strong labelling of exocrine glandularelements but no reactivity of islets of Langerhans (IL).

The higher power view shows that labelling is principally confined to the luminal aspect of the glandular cells.

Cordell, J., Richardson, T. C., Pulford, K. A., Ghosh, A. K., Gatter, K. C., Heyderman, E., & Mason, D. Y. (1985). Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. British journal of cancer, 52(3), 347-354.

Figure 3 APAAP staining of kidney with antibody E29 shows strong labelling of distal tubules but noreactivity of proximal tubules or gomeruli.

Figure 3 APAAP staining of kidney with antibody E29 shows strong labelling of distal tubules but noreactivity of proximal tubules or gomeruli.

Cordell, J., Richardson, T. C., Pulford, K. A., Ghosh, A. K., Gatter, K. C., Heyderman, E., & Mason, D. Y. (1985). Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. British journal of cancer, 52(3), 347-354.

Figure 4 APAAP staining of prostate with antibody E29. A strongly labelled glandular structure is seen,with labelling principally on the luminal aspect of the cells. The intensity of the labelling varies markedly inthe prostate, some glandular elements showing no reactivity with antibody E29.

Figure 4 APAAP staining of prostate with antibody E29. A strongly labelled glandular structure is seen,with labelling principally on the luminal aspect of the cells. The intensity of the labelling varies markedly inthe prostate, some glandular elements showing no reactivity with antibody E29.

Cordell, J., Richardson, T. C., Pulford, K. A., Ghosh, A. K., Gatter, K. C., Heyderman, E., & Mason, D. Y. (1985). Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. British journal of cancer, 52(3), 347-354.

Figure 5 APAAP staining of normal mesothelium with antibody E29 shows strong staining of the cellsurface.

Figure 5 APAAP staining of normal mesothelium with antibody E29 shows strong staining of the cellsurface.

Cordell, J., Richardson, T. C., Pulford, K. A., Ghosh, A. K., Gatter, K. C., Heyderman, E., & Mason, D. Y. (1985). Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. British journal of cancer, 52(3), 347-354.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1
  • Species Reactivity
  • Human
  • Clone
  • E29
  • Applications
  • WB, IHC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Mucin 1, Cell Surface Associated; Tumor-Associated Epithelial Membrane Antigen; Breast Carcinoma-Associated Antigen DF3; Peanut-Reactive Urinary Mucin; Polymorphic Epithelial Mucin; Carcinoma-Associated Mucin; Mucin 1, Transmembrane; Krebs Von Den Lungen-6; Cancer Antigen 15-3; Episialin; CA 15-3; H23AG; MUC-1; KL-6; PEMT; EMA; PUM; PEM

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone E29"

See other products for "MUC1"

Humanized Antibody

CAT Product Name Application Type
TAB-166 Humanized Anti-MUC1 Recombinant Antibody (clone Cantuzumab) IP, IF, FuncS, FC, Neut, ELISA, ICC Humanized (from mouse) IgG1, κ
TAB-037-F(E) Anti-Human MUC1 Recombinant Antibody Fab Fragment (Clivatuzumab Tetraxetan) Neut, ELISA, IF, IP, FuncS, FC, IHC Fab - G1 - kappa
TAB-413MZ Human Anti-MUC1 Recombinant Antibody (TAB-413MZ) ELISA Humanized IgG
TAB-425MZ Anti-Human MUC1 Recombinant Antibody (huDMB5F3) ELISA, FC, FuncS, ICC Humanized antibody
TAB-430MZ Anti-Human MUC1 Recombinant Antibody (BLC595) ELISA, FC Humanized antibody

Immunotoxin

CAT Product Name Application Type
AGTO-L036E anti-MUC1 immunotoxin C242 (Fab)-PE Cytotoxicity assay, Functional assay
AGTO-L064E anti-MUC1 immunotoxin H23 (scFv)-PE Cytotoxicity assay, Functional assay

Fab Glycosylation

CAT Product Name Application Type
Gly-012LC Recombinant Anti-Human MUC1 Antibody (Fab glycosylation/Sialylated) ELISA, FC, IHC Humanized antibody
Gly-120LC Recombinant Anti-Human MUC1 Antibody (Fab glycosylation) ELISA Mouse antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-012LC-1 Recombinant Anti-Human MUC1 Antibody (Fab glycosylation/Sialylated) ELISA, FC, IHC Humanized antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-109LC Recombinant Anti-Human MUC1 Antibody (Fc glycosylation) ELISA Human antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0379MZ Chicken Anti-MUC1 Polyclonal IgY IHC, WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2320 Hi-Affi™ Recombinant Rabbit Anti-MUC1 Monoclonal Antibody (DS2320AB) IHC-P, IHC-Fr IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H56 Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Pemtumomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-H65 Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Sontuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF ADCC enhanced antibody
AFC-TAB-026ML Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Gatipotuzumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-166 Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Cantuzumab), ADCC Enhanced IP, IF, FuncS, FC, Neut, ELISA ADCC enhanced antibody
AFC-TAB-H77 Afuco™ Human Anti-MUC1 Recombinant Antibody, ADCC Enhanced (AFC-TAB-H77) ELISA, FC, IP, FuncS, IF IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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