Human Anti-MUC1 Recombinant Antibody (clone G8) (CAT#: FAMAB-0211JF)
Recombinant monoclonal antibody specially binds to human MUC1. This human anti-MUC1 (G8) can contribute to our understanding of the research of poor clinical prognosis.
Specific Inquiry
IHC
Figure 1 Immunohistochemical staining of breast cancer sections by anti-MUC1 VNTR MAb.
Analysis of the antigenicity and specificity of MUC1 as detecting antigen.
Richards, E. R., Devine, P. L., Quin, R. J., Fontenot, J. D., Ward, B. G., & McGuckin, M. A. (1998). Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women. Cancer Immunology, Immunotherapy, 46(5), 245-252.
WB
Figure 2 The serum reactivity to 8R-MUCPT could be abolished by preincubation with anti-MUC1VNTR MAb but not by preincubation with anti-HBSAg MAb.
Dot blot and inhibition test. 8R-MUCPT was spotted onto a nitrocellulose filter in four dosages.
Richards, E. R., Devine, P. L., Quin, R. J., Fontenot, J. D., Ward, B. G., & McGuckin, M. A. (1998). Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women. Cancer Immunology, Immunotherapy, 46(5), 245-252.
ELISA
Figure 3 CI-ELISA. 8R-MUCPT was captured by anti-MUC1 VNTR MAb as a coating antigen.
The serum samples were directly added into the wells or mixed with three different concentrations of anti-MUC1 VNTR MAb.
Richards, E. R., Devine, P. L., Quin, R. J., Fontenot, J. D., Ward, B. G., & McGuckin, M. A. (1998). Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women. Cancer Immunology, Immunotherapy, 46(5), 245-252.
Block
Figure 4 Blocking experiment. The sera of four patients with breast cancer were mixed with 8R-MUCPT, poly-R, or poly-H in equal molar rations, and then their anti-MUC1 antibody levels were detected by the I-ELISA.
The serum reactivity to 8R-MUCPT in an I-ELISA could be blocked by being mixed with 8R-MUCPT, but poly-R or poly-H could not block this reactivity.
Richards, E. R., Devine, P. L., Quin, R. J., Fontenot, J. D., Ward, B. G., & McGuckin, M. A. (1998). Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women. Cancer Immunology, Immunotherapy, 46(5), 245-252.
Specifications
- Immunogen
- Tetanus toxoid
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human IgG
- Specificity
- Human MUC1
- Species Reactivity
- Human
- Clone
- G8
- Applications
- WB, ELISA, IHC, Block
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The MUC1 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Blocking.
Target
- Alternative Names
- EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2049-VHH | Recombinant Anti-human MUC1 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| HPAB-AP504-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP504-YC) | FC | Camel VHH |
| HPAB-AP505-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP505-YC) | ELISA | Camel VHH |
| HPAB-0736-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0736-YJ-VHH) | ELISA | Camelid VHH |
| HPAB-0737-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0737-YJ-VHH) | ELISA | Camelid VHH |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L036E | anti-MUC1 immunotoxin C242 (Fab)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L064E | anti-MUC1 immunotoxin H23 (scFv)-PE | Cytotoxicity assay, Functional assay |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0278CL | Human Anti-MUC1 Recombinant Antibody (TAB-0278CL) | ELISA, Internalization, BI, FuncS | Human IgG |
| TAB-0278CL-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-0278CL-F(E)) | ELISA, Internalization, BI, FuncS | Human Fab |
| PABX-143 | Recombinant Human Anti-MUC1 Antibody (CTM01) | WB, ELISA, FuncS | IgG |
| PABX-143-S (P) | Recombinant Human Anti-MUC1 Antibody scFv Fragment (CTM01) | WB, ELISA, FuncS | scFv |
| PABX-143-F (E) | Recombinant Human Anti-MUC1 Antibody Fab Fragment (CTM01) | WB, ELISA, FuncS | Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0388CL | Mouse Anti-Human MUC1 Recombinant Antibody | WB, IHC | |
| TAB-411MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-411MZ-F(E)) | ELISA | Mouse Fab |
| TAB-416MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-416MZ-F(E)) | IF | Mouse Fab |
| TAB-417MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-417MZ-F(E)) | IF | Mouse Fab |
| PABX-183-S (P) | Recombinant Mouse Anti-MUC1 Antibody scFv Fragment (CTM01) | Neut, FuncS | scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-412MZ | Human Anti-MUC1 Recombinant Antibody (TAB-412MZ) | ELISA | Chimeric (mouse/human) IgG |
| TAB-412MZ-S(P) | Mouse Anti-MUC1 Recombinant Antibody; scFv Fragment (TAB-412MZ-S(P)) | ELISA | Mouse scFv |
| TAB-412MZ-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-412MZ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-413MZ-S(P) | Human Anti-MUC1 Recombinant Antibody; scFv Fragment (TAB-413MZ-S(P)) | ELISA | Humanized scFv |
| TAB-425MZ-S(P) | Anti-Human MUC1 Recombinant Antibody scFv Fragment (huDMB5F3) | FC | Humanized antibody |
| TAB-430MZ-S(P) | Anti-Human MUC1 Recombinant Antibody scFv Fragment (BLC595) | ELISA, FC | Humanized antibody |
| TAB-430MZ-F(E) | Anti-Human MUC1 Recombinant Antibody Fab Fragment (BLC595) | ELISA, FC | Humanized antibody |
| TAB-026ML | Anti-Human MUC1 Recombinant Antibody (Gatipotuzumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-012LC | Recombinant Anti-Human MUC1 Antibody (Fab glycosylation/Sialylated) | ELISA, FC, IHC | Humanized antibody |
| Gly-120LC | Recombinant Anti-Human MUC1 Antibody (Fab glycosylation) | ELISA | Mouse antibody |
Sialylated IgG Glycan
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-012LC-1 | Recombinant Anti-Human MUC1 Antibody (Fab glycosylation/Sialylated) | ELISA, FC, IHC | Humanized antibody |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-109LC | Recombinant Anti-Human MUC1 Antibody (Fc glycosylation) | ELISA | Human antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-121LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
| Gly-122LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
| Gly-123LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
| Gly-124LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0379MZ | Chicken Anti-MUC1 Polyclonal IgY | IHC, WB | Chicken antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC054 | PE-A*02:01/Human MUC1 (LLLTVLTVV) MHC Tetramer | FCM | |
| MHC-LC055 | APC-A*02:01/Human MUC1 (LLLTVLTVV) MHC Tetramer | FCM | |
| MHC-LC781 | A*0201/Human MUC-1 (LLLLTVLTV) MHC Tetramer | FCM | |
| MHC-YF272 | A*02:01/Human MUC1 (LLLLTVLTV) MHC Monomer | MHC Multimer | |
| MHC-YF570 | A*02:01/Human Mucin (TLAPATEPA) MHC Pentamer | FCM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2320 | Hi-Affi™ Recombinant Rabbit Anti-MUC1 Monoclonal Antibody (DS2320AB) | IHC-P, IHC-Fr | IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0838LC | Recombinant Mouse Anti-Human MUC1 Antibody (SM3) | ELISA | IgG1 |
| EPAF-0581CQ | Recombinant Mouse Anti-Human MUC1 Antibody (B27.29) | Neut, FC | IgG1 |
| EPAF-0583CQ | Recombinant Mouse Anti-Human MUC1 Antibody (BC4E549) | Neut, FC | IgG1 |
| EPAF-0584CQ | Recombinant Mouse Anti-Human MUC1 Antibody (DF3) | Neut, FC | IgG1 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0094-YC | Mouse Anti-MUC1 Recombinant Antibody (clone 12D10) | ELISA, FC | Mouse IgG2a |
| PABC-399 | Mouse Anti-MUC1 Recombinant Antibody (clone AR20.5) | ELISA, FC, FuncS | Mouse IgG1 |
| PABC-400 | Mouse Anti-MUC1 Recombinant Antibody (clone SM3) | FC, IHC-Fr, IF, ELISA, IHC-P | Mouse IgG1 |
| HPAB-1159WJ | Mouse Anti-MUC1 Recombinant Antibody (clone 12E) | ELISA | Mouse IgG |
| HPAB-1160WJ | Mouse Anti-MUC1 Recombinant Antibody (clone 3D) | ELISA | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0091-YC-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0091-YC-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0094-YC-F(E) | Mouse Anti-MUC1 Recombinant Antibody (clone 12D10); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0872LY-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0872LY-F(E)) | ELISA, WB, FC | Mouse Fab |
| HPAB-0873LY-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0873LY-F(E)) | ELISA, WB, FC | Humanized Fab |
| HPAB-0874LY-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0874LY-F(E)) | ELISA, WB, FC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0225-YC-S(P) | Mouse Anti-MUC1 Recombinant Antibody (clone MUSE11); scFv Fragment | IHC | Mouse scFv |
| PSBC-399 | Mouse Anti-MUC1 Recombinant Antibody (clone AR20.5); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
| PSBC-400 | Mouse Anti-MUC1 Recombinant Antibody (clone SM3); scFv Fragment | FC, IHC-Fr, IF, ELISA, IHC-P | Mouse scFv |
| HPAB-0495-FY-S(P) | Human Anti-MUC1 Recombinant Antibody; scFv Fragment (HPAB-0495-FY-S(P)) | ELISA | Human scFv |
| FAMAB-0211JF-S(P) | Human Anti-MUC1 Recombinant Antibody (clone G8); scFv Fragment | ELISA, FuncS | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H56 | Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Pemtumomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-H65 | Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Sontuzumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-026ML | Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Gatipotuzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-166 | Afuco™ Anti-MUC1 ADCC Recombinant Antibody (Cantuzumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-H77 | Afuco™ Human Anti-MUC1 Recombinant Antibody, ADCC Enhanced (AFC-TAB-H77) | ELISA, FC, IP, FuncS, IF | IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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