Mouse Anti-Sheep PRNP Recombinant Antibody (clone 2G11) (CAT#: VS-0224-XY113)
The product is a mouse monoclonal antibody which binds to sheep prion protein (PRNP). It was purified by protein G resins. It has been determined by Enzyme-linked immunosorbent assay and Immunohistochemistry.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg
(Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg
Figure 4 Caudate
(Neuronal cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg
(Neuronal cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg
Figure 5 Colon
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
Figure 6 RNA cell line category: Cell line enhanced (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
Specifications
- Immunogen
- Synthetic peptide 146-R154R171-182 of ovine PrP
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Sheep PRNP
- Species Reactivity
- Sheep
- Clone
- 2G11
- Applications
- ELISA, Immunohistochemistry
- Related Disease
- Creutzfeldt-Jakob Disease; Fatal Familial Insomnia
Product Property
- Purification
- Protein G purified
- Buffer
- PBS
- Preservative
- 0.09% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested in ELISA (1/1000).
Target
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PRNP"
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B034(A) | Recombinant Anti-human PRNP Intrabody [(D-Arg)9] | IF, FC, WB, FuncS | scFv-(D-Arg)9 |
| IAB-B034(G) | Recombinant Anti-human PRNP Intrabody [+36 GFP] | WB, CO-IP, FuncS | scFv-(+36GFP) |
| IAB-B034(T) | Recombinant Anti-human PRNP Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-310 | Mouse Anti-PRNP Recombinant Antibody (clone POM2) | WB, IHC, FuncS | Mouse IgG |
| PABC-107 | Mouse Anti-PRNP Recombinant Antibody (clone ICSM 18) | ELISA, Inhib, IF | Mouse IgG |
| PABW-107 | Mouse Anti-PRNP Recombinant Antibody (clone VRQ14) | ELISA | Mouse IgG2a |
| PABX-161 | Mouse Anti-PRNP Recombinant Antibody (clone POM1) | ELISA, IP, IHC, FuncS | Mouse IgG1 |
| FAMAB-0272CQ | Human Anti-PRNP Recombinant Antibody (clone ch31C6) | ELISA, WB, IHC | Chimeric (mouse/human) IgG1 |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-026 | Recombinant Anti-Human PRNP VHH Single Domain Antibody (PNBL-026) | WB, ELISA, FuncS | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-943LC | Anti-Mouse Prnp Recombinant Antibody (D13) | ELISA | Human antibody |
| MRO-944LC | Anti-Mouse Prnp Recombinant Antibody (D18) | ELISA | Human antibody |
| MRO-945LC | Anti-Mouse Prnp Recombinant Antibody (R72) | ELISA | Human antibody |
| MRO-946LC | Anti-Mouse Prnp Recombinant Antibody (R1) | ELISA | Human antibody |
| MRO-947LC | Anti-Mouse Prnp Recombinant Antibody (R2) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-948LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (6H10) | ELISA | Mouse antibody |
| MRO-949LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (31C6) | ELISA | Mouse antibody |
| MRO-950LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (72-5) | ELISA | Mouse antibody |
| MRO-951LC-S(P) | Anti-Mouse Prnp Recombinant Antibody scFv Fragment (44B1) | ELISA | Mouse antibody |
| MRO-952LC-S(P) | Mouse Anti-Prnp Recombinant Antibody; scFv Fragment (MRO-952LC-S(P)) | ELISA | Mouse scFv |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0727MZ | Chicken Anti-PRNP Polyclonal IgY | ICC/IF | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2871 | Hi-Affi™ Recombinant Rabbit Anti-PRNP Monoclonal Antibody (DS2871AB) | WB, FC, IHC-P, ICC/IF | IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0275CQ | Mouse Anti-PRNP Recombinant Antibody (clone E123) | FC, ELISA | Mouse IgG |
| EPAF-0276CQ | Mouse Anti-PRNP Recombinant Antibody (clone E149) | FC, ELISA | Mouse IgG |
| EPAF-0277CQ | Mouse Anti-PRNP Recombinant Antibody (clone 4H8) | Inhib | Mouse IgG2b |
| EPAF-0278CQ | Mouse Anti-PRNP Recombinant Antibody (clone 6BH) | Inhib | Mouse IgG1 |
| EPAF-0279CQ | Mouse Anti-PRNP Recombinant Antibody (clone 3F10) | WB | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0272CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone ch31C6); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0273CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 106); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0274CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 110); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0275CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 132); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| HPAB-1462LY-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone CBL030); scfv Fragment | ELISA, WB, Inhib | Mouse scfv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0294-CN-F(E) | Human Anti-PRNP Recombinant Antibody (clone D18); Fab Fragment | WB, IF, IHC | Human Fab |
| FAMAB-0295-CN-F(E) | Human Anti-PRNP Recombinant Antibody (clone 3:3); Fab Fragment | WB, IF, IHC | Human Fab |
| FAMAB-0296-CN-F(E) | Human Anti-PRNP Recombinant Antibody (clone 6:4); Fab Fragment | WB, IF, IHC | Human Fab |
| FAMAB-0297-CN-F(E) | Human Anti-PRNP Recombinant Antibody (clone 6:6); Fab Fragment | WB, IF, IHC | Human Fab |
| HPAB-1462LY-F(E) | Mouse Anti-PRNP Recombinant Antibody (clone CBL030); Fab Fragment | ELISA, WB, Inhib | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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