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ERAS
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatogonia, Spermatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Interacts with PIK3CD.
Molecular function
Hydrolase
More Types Infomation
- Mouse Anti-ERAS Recombinant Antibody (clone D10-B9) (MRO-0540-CN)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IF, IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.