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FOLR1 & CD3

Anti-FOLR1 & CD3 Products

Anti-Human folate receptor 1 Recombinant Antibody (TAB-113) (TAB-113)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P)) (TAB-0416CL-S(P))
- Application: IB, ELISA, FC, FuncS
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Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (TAB-0416CL)
- Application: FC, IB, ELISA
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Humanized Anti-Human CD3 Recombinant Antibody (TAB-0418CL)
- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
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Rat Anti-CD3 Recombinant Antibody (clone 17A2) (MOB-0202MC)
- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IHC, IP, Activ, CMCD, Depletion
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Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-071LC-F(E))
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-072LC-F(E))
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-075LC-S(P)) (TAB-075LC-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-076LC-S(P)) (TAB-076LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-077LC-S(P)) (TAB-077LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-078LC-S(P)) (TAB-078LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-079LC-S(P)) (TAB-079LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-080LC-S(P)) (TAB-080LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-081LC-S(P)) (TAB-081LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-083LC-S(P)) (TAB-083LC-S(P))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-084LC-S(P)) (TAB-084LC-S(P))
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-085LC-S(P)) (TAB-085LC-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-018CQ-F(E)) (TAB-018CQ-F(E))
- Derivation: Chimeric (Rat/Human)
- Species Reactivity: Human, Cynomolgus
- Type: Chimeric (Rat/Human) Fab
- Application: ELISA, WB, IHC
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Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-016CQ-F(E)) (TAB-016CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, WB
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Mouse Anti-FOLR1 Recombinant Antibody (clone LK26) (MOB-098CQ)
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FC, IHC, WB, IP
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Human Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-0532CL-S(P))
- Type: Human antibody
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Human Anti-CD3 Recombinant Antibody (TAB-080LC) (TAB-080LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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Human Anti-CD3 Recombinant Antibody (TAB-081LC) (TAB-081LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC
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Human Anti-CD3 Recombinant Antibody (TAB-083LC) (TAB-083LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC
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Human Anti-CD3 Recombinant Antibody (TAB-078LC) (TAB-078LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-072LC-S(P))
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody (TAB-079LC) (TAB-079LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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Human Anti-Human CD3 Recombinant Antibody (TAB-0532CL)
- Type: Human antibody
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-118CL) (TAB-118CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Fab fragment
- Application: ELISA
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Mouse Anti-FOLR1 Recombinant Antibody (clone 24A8) (MOB-1297z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, FC, ICC, IF, IHC
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Anti-Human CD3 Recombinant Antibody (TAB-071LC)
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Chimeric Anti-Human CD3 Recombinant Antibody (TAB-072LC)
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody (TAB-075LC) (TAB-075LC)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC
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Human Anti-CD3 Recombinant Antibody (TAB-076LC) (TAB-076LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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Human Anti-CD3 Recombinant Antibody (TAB-077LC) (TAB-077LC)
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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Human Anti-CD3 Recombinant Antibody (TAB-084LC) (TAB-084LC)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
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Anti-Human CD3 Recombinant Antibody (TAB-085LC) (TAB-085LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
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Anti-Human CD3 Recombinant Antibody (TAB-086LC) (TAB-086LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CD3 Recombinant Antibody (TAB-087LC) (TAB-087LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CD3 Recombinant Antibody (TAB-088LC) (TAB-088LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CD3 Recombinant Antibody (TAB-089LC) (TAB-089LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
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Anti-Human CD3 Recombinant Antibody (TAB-090LC) (TAB-090LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
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Anti-Human CD3 Recombinant Antibody (TAB-091LC) (TAB-091LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CD3 Recombinant Antibody (TAB-092LC) (TAB-092LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-Human CD3 Recombinant Antibody (TAB-093LC) (TAB-093LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Human Anti-CD3 Recombinant Antibody (TAB-094LC) (TAB-094LC)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, WB
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Human Anti-CD3 Recombinant Antibody (TAB-095LC) (TAB-095LC)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, WB
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Human Anti-CD3 Recombinant Antibody (TAB-096LC) (TAB-096LC)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, WB
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Human Anti-CD3 Recombinant Antibody (TAB-098LC) (TAB-098LC)
- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus Monkey
- Type: Humanized IgG
- Application: ELISA, SPR
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-075LC-F(E)) (TAB-075LC-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-076LC-F(E)) (TAB-076LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-077LC-F(E)) (TAB-077LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-078LC-F(E)) (TAB-078LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-079LC-F(E)) (TAB-079LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-080LC-F(E)) (TAB-080LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-081LC-F(E)) (TAB-081LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-083LC-F(E)) (TAB-083LC-F(E))
- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-019CQ-F(E)) (TAB-019CQ-F(E))
- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus
- Type: Humanized Fab
- Application: ELISA, WB, IHC
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Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-020CQ-F(E)) (TAB-020CQ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, WB, IHC
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Mouse Anti-CD3 Recombinant Antibody (TAB-097LC) (TAB-097LC)
- Species Reactivity: Cynomolgus, Human
- Type: Mouse IgG
- Application: ELISA, SPR
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Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0668LY-S(P)) (HPAB-0668LY-S(P))
- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
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Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-070LC-S(P)) (TAB-070LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-CD3 Recombinant Antibody (TAB-073LC) (TAB-073LC)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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Mouse Anti-CD3 Recombinant Antibody (TAB-074LC) (TAB-074LC)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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Anti-Mouse CD3 Recombinant Antibody (Dow2) (TAB-0365CL)
- Application: FC, IHC
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Mouse Anti-CD3 Recombinant Antibody (TAB-070LC) (TAB-070LC)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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Anti-α-FR Antibody-Cytokine Fusion Protein, IL2-scFv (MOV19) (ACFP-SH052)
- Target: α-FR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: IL2-scFv
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Mouse Anti-CD3 Recombinant Antibody (TAB-099LC) (TAB-099LC)
- Species Reactivity: Cynomolgus, Human
- Type: Mouse IgG
- Application: ELISA, SPR
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Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-073LC-S(P)) (TAB-073LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-074LC-S(P)) (TAB-074LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-CD3 Recombinant Antibody (clone G3(3)); scFv Fragment (FAMAB-0053-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, IHC
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Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0667LY-S(P)) (HPAB-0667LY-S(P))
- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
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Rat Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-017CQ-F(E)) (TAB-017CQ-F(E))
- Species Reactivity: Human, Cynomolgus
- Type: Rat Fab
- Application: ELISA, WB, IHC
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Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-540CT-S(P)) (TAB-540CT-S(P))
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-540CT-F(E)) (TAB-540CT-F(E))
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0115-CN-F(E)) (HPAB-0115-CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC
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Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0116-CN-F(E)) (HPAB-0116-CN-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, IHC
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Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0117-CN-F(E)) (HPAB-0117-CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0118-CN-F(E)) (HPAB-0118-CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0119-CN-F(E)) (HPAB-0119-CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, WB
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Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0120-CN-F(E)) (HPAB-0120-CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, WB
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Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0121-CN-F(E)) (HPAB-0121-CN-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, IHC, WB
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Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0122-CN-F(E)) (HPAB-0122-CN-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, IHC, WB
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Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-070LC-F(E)) (TAB-070LC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-073LC-F(E)) (TAB-073LC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-074LC-F(E)) (TAB-074LC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) (TAB-0365CL-S(P))
- Application: IP, IB, FuncS
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Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation) (Gly-116LC)
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation
- Glycosylation site: Fc region
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Anti-FOLR1 (Mirvetuximab)-sulfo-SPDB-DM4 ADC (IMGN853) (ADC-L018)
- Target: FOLR1
- Linker: sulfo-SPDB (sulfosuccinimidyl N-succinimidyl-4-(2-pyridyldithio)butyrate)
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4- methyl-1-oxopentyl)maytansine)
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Recombinant Anti-FOLR1 × Anti-CD3 Bispecific Antibody (Fab₂) (FAB-L067)
- Targets: FOLR1 & CD3
- Type: Fab₂
- Application: FuncS, Promising therapeutic agent
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Anti-FOLR1 (M9346A)-sulfo-SPDB-DM4 ADC (ADC-119LCT)
- Target: FOLR1
- Linker: sulfo-SPDB
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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Anti-FRα-DGN462 ADC (ADC-120LZY)
- Target: FRα
- Linker: maleimide containing linkers
- Drug: DGN462
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Recombinant Anti-FOLR1 × Anti-CD3 Bispecific Antibody (Tandem Diabody) (TAND-L059)
- Targets: FOLR1 & CD3
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
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Anti-FRα (clone M9346A)-SPDB-DM4 ADC (ADC-073LZY)
- Target: FRα
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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Recombinant Anti-human FOLR1 Intrabody [(D-Arg)₉] (IAB-B029(A))
- Species Reactivity: human
- Type: scFv-(D-Arg)₉
- Application: PCA, Neut, FuncS
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Anti-FR-S-S-Dox ADC (ADC-170LZY)
- Target: folate receptor (FR)
- Linker: disulfide ("S-S") linker
- Drug: doxorubicin
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Recombinant Anti-human FOLR1 Intrabody [+36 GFP] (IAB-B029(G))
- Species Reactivity: human
- Type: scFv-(+36GFP)
- Application: WB, Neut, FuncS
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Recombinant Anti-human FOLR1 Intrabody [Tat] (IAB-B029(T))
- Species Reactivity: human
- Type: scFv-Tat
- Application: WB, ICC, Neut, FuncS
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Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) (Gly-029LC)
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Asn299 of heavy chain
- Glycoform (ratio): NGA2
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Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) (Gly-029LC-1)
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Asn299 of heavy chain
- Glycoform (ratio): NGA2
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For Research Use Only. Not For Clinical Use.

Background

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.