TNF
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: WB, FC, IP, ELISA, Neut, FuncS, IF
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab'
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, Inhib
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, BL
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, IHC
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- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: FC, ELISA
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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- Derivation: Humanized
- Species Reactivity: Human, Rhesus macaque, Cynomolgus, Canine
- Type: Humanized antibody
- Application: ELISA, FC, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: WB
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human, Rhesus macaque, Cynomolgus, Canine
- Type: Human scFv
- Application: ELISA, FC, Neut
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- Species Reactivity: Human, Mouse, Monkey
- Type: Humanized antibody
- Application: FuncS, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, Neut
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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- Species Reactivity: Human, Rhesus macaque, Mouse, Chimpanzee
- Type: Humanized antibody
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, BL
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Human antibody
- Application: Inhib, ELISA
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF
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- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, Neut
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- Species Reactivity: Human, Cynomolgous macaque
- Type: Human IgG
- Application: ELISA, Inhib, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human, Rabbit
- Type: Human IgG1, κ
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human antibody
- Application: ELISA, Neut
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- Species Reactivity: Human, Mouse, Monkey
- Type: Humanized scFv
- Application: ELISA, Neut
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- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human
- Type: [V-kappa]2 - Fc
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human, Rhesus macaque, Mouse, Chimpanzee
- Type: Humanized scFv
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC, IF
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Neut
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- Species Reactivity: Human
- Application: Inhib, ELISA
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- Species Reactivity: Human
- Application: ELISA, FC, Neut
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- Species Reactivity: Human
- Application: ELISA
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- Species Reactivity: Human
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, WB
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- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut, FunS
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- Species Reactivity: Human
- Application: ELISA
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- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut
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- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Application: ELISA, WB
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- Species Reactivity: Human
- Application: ELISA, WB
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- Species Reactivity: Human, Mouse
- Type: Single domain antibody
- Application: ELISA, Inhib
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- Species Reactivity: Human
- Application: Neut, ELISA, WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, IHC, FC, FuncS
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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- Species Reactivity: Human
- Type: Bovine IgG
- Application: Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: F(ab')2 - G3 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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