Anti-TNFα Recombinant Antibody (TAB-718)

Name: Anti-TNFα Recombinant Antibody (TAB-718)
SKU: TAB-718
Rating: 5 (1 reviews)

CAT#: TAB-718

Recombinant mouse monoclonal antibody F(ab')₂ fragment expressed in CHO binding to human TNFα. It is an anti-TNFα monoclonal antibody. Administration of it reduces the concentration of interleukin-6 in patients with sepsis, but reduces mortality only marginally.

Gene Expression

Normal Tissue Figure 1 Tonsil

Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Mouse

Derivation
Mouse

Type
F(ab')2 - G3 - kappa

Species Reactivity
Human

Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.

Related Disease
Sepsis toxic shock

Product Property

Purity
Purity >95% by SDS-PAGE.

Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.

Target

Alternative Names
Afelimomab;156227-98-4;MAK 195F;LU54107;MAK 195F;TNF;tumor necrosis factor;TNFA, tumor necrosis factor (TNF superfamily, member 2);DIF;TNF superfamily;member 2;TNF alpha;TNFSF2;TNF-a;cachectin;APC1 protein;TNF, monocyte-derived;TNF, macrophage-derived;TNF

Gene ID
7124

UniProt ID
P01375

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Biosimilar Overview

Please refer to Afelimomab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Afelimomab.

Related Diseases

Asthma

Inflammatory Bowel Diseases

Related Signaling Pathways

TNF Signaling Pathway

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-718.pdf

MSDS

MSDS - TAB-718.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
TAB-148CQ	Anti-Human TNF Recombinant Antibody	ELISA	Chimeric antibody (mouse/human)
TAB-402CQ	Human Anti-TNF Recombinant Antibody (TAB-402CQ)	ELISA	Chimeric (mouse/human) IgG
TAB-148CQ-S(P)	Anti-Human TNF Recombinant Antibody scFv Fragment	ELISA	Chimeric antibody (mouse/human)
TAB-402CQ-S(P)	Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P))	ELISA	Mouse scFv
TAB-148CQ-F(E)	Anti-Human TNF Recombinant Antibody Fab Fragment	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
TAB-111CQ-F(E)	Anti-Human TNF Recombinant Antibody Fab Fragment (B5)	ELISA, WB	Human antibody
TAB-113CQ-F(E)	Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-113CQ-F(E))	ELISA	Human Fab
TAB-119CQ-F(E)	Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-119CQ-F(E))	ELISA, BL	Human Fab
TAB-120CQ-F(E)	Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-120CQ-F(E))	ELISA, Neut	Human antibody
TAB-121CQ-F(E)	Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-121CQ-F(E))	ELISA, Neut	Human antibody

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CAT	Product Name	Application	Type
Gly-083LC-1	Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated)	ELISA, FC	Human antibody

CAT	Product Name	Application	Type
Gly-085LC-1	Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated)	ELISA, FC	Human antibody
Gly-163LC-1	Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
Gly-086LC-1	Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated)	ELISA, FC	Human antibody
Gly-087LC-1	Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated)	ELISA, FC	Human antibody

CAT	Product Name	Application	Type
MOB-0229MZ	Recombinant Mouse Anti-Human TNF Antibody (clone G7C6)	ELISA, IHC	Mouse antibody
MOB-169CQ	Goat Anti-TNF Polyclonal Antibody, Biotin	WB, ELISA(Det), ICC	Goat IgG
MOB-170CQ	Mouse Anti-TNF Recombinant Antibody (clone YC146), Biotin	Neut, ELISA, ICC, FC	Mouse IgG1, κ
MRO-2233-CN	Rabbit Anti-TNF Polyclonal Antibody (MRO-2233-CN)	WB, IF, IHC, FC, ELISA	Rabbit IgG
HPAB-M0680-YC	Human Anti-TNF Recombinant Antibody (HPAB-M0680-YC)	ELISA, Neut, Inhib	Humanized IgG

CAT	Product Name	Application	Type
BRD-0609MZ	Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY	Indirect ELISA, WB	Chicken antibody

CAT	Product Name	Application	Type
NEUT-2051CQ	Mouse Anti-TNF Recombinant Antibody (clone CBL589)	ELISA, ICC, Neut	Mouse IgG1
NEUT-2052CQ	Mouse Anti-TNF Recombinant Antibody (clone CBL570)	WB, Neut	Mouse IgG2b
NEUT-2053CQ	Mouse Anti-TNF Recombinant Antibody (clone CBL571)	WB, Neut	Mouse IgG1
NEUT-2054CQ	Rat Anti-Tnf Recombinant Antibody (NEUT-2054CQ)	Neut	Rat IgG1
NEUT-2055CQ	Rat Anti-Tnf Recombinant Antibody (NEUT-2055CQ)	Neut, FC	Rat IgD

CAT	Product Name	Application	Type
NEUT-2057CQ	Rat Anti-Tnf Recombinant Antibody (NEUT-2057CQ)	Block, ELISA, IHC, WB	Rat IgG1
NEUT-2070CQ	Mouse Anti-TNF Recombinant Antibody (clone 4F4)	Block, ELISA, ICC, IF, IHC, WB	Mouse IgG1
NEUT-2071CQ	Rabbit Anti-TNF Recombinant Antibody (clone 6E10)	Block, ELISA, IHC, WB	Rabbit IgG1
NEUT-2082CQ	Mouse Anti-TNF Recombinant Antibody (clone B-C7)	Block	Mouse IgG1

CAT	Product Name	Application	Type
MOR-3602	Rabbit Anti-Tnf Recombinant Antibody (clone DS3602AB)	ELISA, WB	Rabbit IgG
MOR-4460	Rabbit Anti-TNF Recombinant Antibody (clone SI554DS)	ELISA	Rabbit IgG
MOR-4461	Rabbit Anti-TNF Recombinant Antibody (clone SI555DS)	Neut	Rabbit IgG
MOR-4751	Rabbit Anti-Tnf Recombinant Antibody (clone TH265DS)	WB	Rabbit IgG
MOR-4752	Rabbit Anti-TNF Recombinant Antibody (clone TH266DS)	ELISA	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0007-YC-F(E)	Human Anti-TNF Recombinant Antibody (clone cA2); Fab Fragment	ELISA, Neut	Human Fab
HPAB-0046-FY-F(E)	Mouse Anti-TNF Recombinant Antibody (clone 1B7); Fab Fragment	Neut	Mouse Fab
HPAB-0321CQ-F(E)	Human Anti-TNF Recombinant Antibody (clone mAb A1); Fab Fragment	ELISA, Neut	Human Fab
HPAB-0322CQ-F(E)	Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0322CQ-F(E))	ELISA, FC, Inhib	Rat Fab
HPAB-M0680-YC-F(E)	Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-M0680-YC-F(E))	ELISA, Neut, Inhib	Humanized Fab

CAT	Product Name	Application	Type
HPAB-M0680-YC-S(P)	Human Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-M0680-YC-S(P))	ELISA, Neut, Inhib	Human scFv
HPAB-M0681-YC-S(P)	Human Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-M0681-YC-S(P))	ELISA, Neut, Inhib	Human scFv
HPAB-0303-WJ-S(P)	Human Anti-TNF Recombinant Antibody scFv Fragment (HPAB-0303-WJ-S(P))	ELISA	Human scFv
HPAB-N0266-YC-S(P)	Human Anti-TNF Recombinant Antibody (clone NOV005YC); scFv Fragment	ELISA, Neut	Human scFv
HPAB-N0267-YC-S(P)	Human Anti-TNF Recombinant Antibody scFv Fragment (HPAB-N0267-YC-S(P))	FuncS	Human scFv

CAT	Product Name	Application	Type
AFC-TAB-768	Afuco™ Anti-TNF ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-768)	FuncS, IF, Neut, ELISA, FC, IP	ADCC enhanced antibody
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AFC-TAB-010	Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced	FC, IP, ELISA, Neut, FuncS	ADCC enhanced antibody

CAT	Product Name	Application	Type
HPAB-AP531-YC	Camel Anti-TNF Recombinant Antibody (HPAB-AP531-YC)	ELISA	Camel VHH
HPAB-AP532-YC	Camel Anti-TNF Recombinant Antibody (HPAB-AP532-YC)	ELISA	Camel VHH
HPAB-AP533-YC	Camel Anti-TNF Recombinant Antibody (HPAB-AP533-YC)	ELISA	Camel VHH
HPAB-AP534-YC	Camel Anti-TNF Recombinant Antibody (HPAB-AP534-YC)	ELISA	Camel VHH
HPAB-AP535-YC	Camel Anti-TNF Recombinant Antibody (HPAB-AP535-YC)	ELISA	Camel VHH

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VS-0424-XY256	AbPlus™ Anti-TNF Magnetic Beads (4H31)	IP, Protein Purification
VS-0724-YC1214	AbPlus™ Anti-TNF Magnetic Beads (VS-0724-YC1214)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0125-FY32	Human Anti-TNF (clone BPC1500) scFv-Fc Chimera	ELISA, Neut	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0225-XY215	CytoStream™ Mouse Anti-TNF Recombinant Antibody (clone MAb11)	FC	Mouse IgG1, kappa
VS-0225-XY216	CytoStream™ Armenian Hamster Anti-TNF Recombinant Antibody (clone TN3-19.12)	ELISA, FC, Neut, IP, WB	Armenian Hamster IgG

CAT	Product Name	Application
VS-0325-XY2313	Anti-TNF Immunohistochemistry Kit	IHC
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VS-0525-XY7352	Anti-Human TNF Immunohistochemistry Kit	IHC
VS-0525-XY7353	Anti-Rat TNF Immunohistochemistry Kit	IHC
VS-0525-XY7355	Anti-Fish TNF Immunohistochemistry Kit	IHC

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