Anti-Human TNF Recombinant Antibody (BPC1494) (CAT#: TAB-404CQ)

Recombinant human monoclonal antibody to TNF. The antibody has reduced capacity to bind FcγRIIIa (V158 and F158 variants).


Specific Inquiry
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  • Published Data
  • Gene Expression
  • Datasheet
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ELISA

Figure 1 Binding of anti-TNFa antibodies to human TNFa.

Figure 1 Binding of anti-TNFa antibodies to human TNFa.

ELISA

Figure 2 Analysis of binding activity of anti-TNFa antibodies to human TNFa following an accelerated stressor study.

Figure 2 Analysis of binding activity of anti-TNFa antibodies to human TNFa following an accelerated stressor study.

ELISA

Figure 3 Binding of anti-TNFa antibodies to human TNFa following incubation in 25% human serum for 2 weeks.

Figure 3 Binding of anti-TNFa antibodies to human TNFa following incubation in 25% human serum for 2 weeks.

ELISA

Figure 4 Binding of anti-TNFa antibodies to human TNFa following freeze-thaw.

Figure 4 Binding of anti-TNFa antibodies to human TNFa following freeze-thaw.

ELISA

Figure 5 Analysis of anti-TNFa antibodies to FcyRllla receptors.

Figure 5 Analysis of anti-TNFa antibodies to FcyRllla receptors.

Binding to human FcvRllla (valine 158 variant)


Specifications

  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human, Cynomolgous monkey
  • Clone
  • BPC1494
  • Applications
  • ELISA
  • Related Disease
  • Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and Crohn's disease

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Chimeric Antibody

CAT Product Name Application Type
TAB-006 Anti-Human TNF Recombinant Antibody (Infliximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-148CQ Anti-Human TNF Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-148CQ-S(P) Anti-Human TNF Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) ELISA Mouse scFv
TAB-402CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) ELISA Chimeric (mouse/human) Fab

Humanized Antibody

CAT Product Name Application Type
TAB-034-F(E) Anti-Human TNF alpha Recombinant Antibody Fab Fragment (Certolizumab Pegol) ELISA, FC, IP, FuncS, IF, Neut, IHC Fab'
TAB-110CQ Anti-Human TNF Recombinant Antibody (CDP571) ELISA Humanized antibody
TAB-114CQ Human Anti-TNF Recombinant Antibody (TAB-114CQ) ELISA, FC, Inhib Humanized antibody
TAB-115CQ Human Anti-TNF Recombinant Antibody (TAB-115CQ) ELISA, FC, Neut Humanized antibody
TAB-118CQ Anti-Human TNF Recombinant Antibody (YHB1411-2) FC, ELISA Humanized antibody

Rat Antibody

CAT Product Name Application Type
TAB-623CL Bovine Anti-TNF Recombinant Antibody (TAB-623CL) Neut Bovine IgG

Single-domain Antibody

CAT Product Name Application Type
TAB-412CQ Anti-Human TNF Therapeutic Single Domain Antibody (TAR1-5-19) ELISA, Inhib Single domain antibody
TAB-413CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL18) ELISA, WB, Neut Single domain antibody
TAB-414CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL11) ELISA, WB, Neut Single domain antibody
TAB-415CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL18-3L-VL11) ELISA, WB, Neut, FunS Single domain antibody
HPAB-M0402-YC Recombinant Chiloscyllium shark Anti-TNF Single Domain Antibody (3D2) ELISA Chiloscyllium shark vNAR single domain antibody

Non-hyper Galactosylated

CAT Product Name Application Type
Gly-083LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-085LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-163LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0609MZ Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY Indirect ELISA, WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2057CQ Rat Anti-Tnf Recombinant Antibody (clone XT3) Block, ELISA, IHC, WB Rat IgG1
NEUT-2070CQ Mouse Anti-TNF Recombinant Antibody (clone 4F4) Block, ELISA, ICC, IF, IHC, WB Mouse IgG1
NEUT-2071CQ Rabbit Anti-TNF Recombinant Antibody (clone 6E10) Block, ELISA, IHC, WB Rabbit IgG1
NEUT-2082CQ Mouse Anti-TNF Recombinant Antibody (clone B-C7) Block Mouse IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-768 Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-006 Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-010 Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced FC, IP, ELISA, Neut, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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