Anti-Human TNF Recombinant Antibody (m357) (CAT#: TAB-130CQ)

Recombinant monoclonal antibody to TNF. The antibody is capable of binding to the cells bearing the transmembrane TNF-α and triggering ADCC with effector cells and CDC. The antibody has TNF-α neutralization activity.


Specific Inquiry
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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 Binding affinities of different TNF-a anatagonists to soluble TNF-a. Microtiter plates with the anti-human IgG Fcc fragment captured h357 (N), etanercept (.) and adalimumab (g) and the anti-mouse IgG Fcc fragment captured m357 (#) were incubated with various concentrations of soluble TNF-a for 1 hr at 37uC.

Figure 1 Binding affinities of different TNF-a anatagonists to soluble TNF-a. Microtiter plates with the anti-human IgG Fcc fragment captured h357 (N), etanercept (.) and adalimumab (g) and the anti-mouse IgG Fcc fragment captured m357 (#) were incubated with various concentrations of soluble TNF-a for 1 hr at 37uC.

Chiu, W. C., Lai, Y. P., & Chou, M. Y. (2011). Humanization and characterization of an anti-human TNF-α murine monoclonal antibody. PLoS One, 6(1), e16373.


Specifications

  • Immunogen
  • Recombinant human TNF-α
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • m357
  • Applications
  • ELISA, FC, Neut
  • Related Disease
  • Autoimmune diseases

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA, Flow Cytometry, Neutralization. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone m357"

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Rat Antibody

CAT Product Name Application Type
TAB-623CL Bovine Anti-TNF Recombinant Antibody (TAB-623CL) Neut Bovine IgG

Humanized Antibody

CAT Product Name Application Type
TAB-124CQ Human Anti-TNF Recombinant Antibody (TAB-124CQ) FuncS, Neut Humanized antibody
TAB-125CQ Human Anti-TNF Recombinant Antibody (TAB-125CQ) ELISA, Neut Humanized antibody
TAB-126CQ Human Anti-TNF Recombinant Antibody (TAB-126CQ) ELISA, Neut Humanized antibody
TAB-127CQ Human Anti-TNF Recombinant Antibody (TAB-127CQ) ELISA, Neut Humanized antibody
TAB-128CQ Human Anti-TNF Recombinant Antibody (TAB-128CQ) ELISA, FuncS Humanized antibody

Chimeric Antibody

Non-hyper Galactosylated

CAT Product Name Application Type
Gly-083LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-085LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-163LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0609MZ Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY Indirect ELISA, WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2057CQ Rat Anti-Tnf Recombinant Antibody (clone XT3) Block, ELISA, IHC, WB Rat IgG1
NEUT-2070CQ Mouse Anti-TNF Recombinant Antibody (clone 4F4) Block, ELISA, ICC, IF, IHC, WB Mouse IgG1
NEUT-2071CQ Rabbit Anti-TNF Recombinant Antibody (clone 6E10) Block, ELISA, IHC, WB Rabbit IgG1
NEUT-2082CQ Mouse Anti-TNF Recombinant Antibody (clone B-C7) Block Mouse IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-768 Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-006 Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-010 Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced FC, IP, ELISA, Neut, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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