Anti-Human TNF Recombinant Antibody (m357) (CAT#: TAB-130CQ)
Recombinant monoclonal antibody to TNF. The antibody is capable of binding to the cells bearing the transmembrane TNF-α and triggering ADCC with effector cells and CDC. The antibody has TNF-α neutralization activity.
Specific Inquiry
FC
Figure 1 Binding affinities of different TNF-a anatagonists to soluble TNF-a. Microtiter plates with the anti-human IgG Fcc fragment captured h357 (N), etanercept (.) and adalimumab (g) and the anti-mouse IgG Fcc fragment captured m357 (#) were incubated with various concentrations of soluble TNF-a for 1 hr at 37uC.
Chiu, W. C., Lai, Y. P., & Chou, M. Y. (2011). Humanization and characterization of an anti-human TNF-α murine monoclonal antibody. PLoS One, 6(1), e16373.
Specifications
- Immunogen
- Recombinant human TNF-α
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- m357
- Applications
- ELISA, FC, Neut
- Related Disease
- Autoimmune diseases
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry, Neutralization. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Chimeric Antibody
Humanized Antibody
Mouse Antibody
Rat Antibody
Single-domain Antibody
Human Antibody
Fc Glycosylation
Non-hyper Galactosylated
Sialylated IgG Glycan
Hyper-galactosylated
Chicken IgY Antibody
Blocking Antibody
Neutralizing Antibody
Rabbit Monoclonal Antibody
Recombinant Antibody
scFv Fragment Antibody
Fab Fragment Antibody
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-006 | Anti-Human TNF Recombinant Antibody (Infliximab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-148CQ | Anti-Human TNF Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-148CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-148CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-402CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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