Anti-Human TNF Recombinant Antibody (mAb2090) (CAT#: TAB-146CQ)

The antibody binds to tumor necrosis factor α (TNFα) and blocks the ability of TNFα to bind to its receptor.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 Anti-TNFα human MAbs 2071 and 2060 compared with Remicade®.

Figure 1 Anti-TNFα human MAbs 2071 and 2060 compared with Remicade®.

Figure 2 Anti-TNFα human MAbs 2071 and 2090 compared with Remicade® and Humira®.

Figure 2 Anti-TNFα human MAbs 2071 and 2090 compared with Remicade® and Humira®.

Figure 3 TNFα receptor blocking assay.

Figure 3 TNFα receptor blocking assay.

Results of the TNFα receptor blocking assay comparing control TNFα antibodies Remicade® and Humira® and anti-TNFα human MAbs 2071 and 2090, and control IgG.

Figure 4 HUVEC assay.

Figure 4 HUVEC assay.

Comparison of inhibition of the TNFα-induced cell surface expression of adhesion molecules with human umbilical vein endothelial cells (HUVEC) using control TNFα antibodies Remicade® and Humira® and anti-TNFα human MAbs 2071, 2090 and 271.

Figure 5 IL8 assay.

Figure 5 IL8 assay.

Measurement of TNFα-induced expression of IL-8 by human monocytes using control TNFα antibodies Remicade® and Humira® and anti-TNFα human MAbs 22071 and 2090, and control IgG.


Specifications

  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • mAb2090
  • Applications
  • ELISA, BL, FC, Neut, WB, Inhib, FuncS
  • Related Disease
  • Rheumatoid arthritis

Applications

  • Application Notes
  • The antibody was validated for ELISA, Blocking, Inhibition and Function assay. For details, refer to Published Data.

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Single-domain Antibody

CAT Product Name Application Type
NABL-051 Recombinant Anti-human TNF VHH Single Domain Antibody WB, ELISA, IHC, FC, FuncS Llama VHH
TAB-412CQ Anti-Human TNF Therapeutic Single Domain Antibody (TAR1-5-19) ELISA, Inhib Single domain antibody
TAB-413CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL18) ELISA, WB, Neut Single domain antibody
TAB-414CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL11) ELISA, WB, Neut Single domain antibody
TAB-415CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL18-3L-VL11) ELISA, WB, Neut, FunS Single domain antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-006 Anti-Human TNF Recombinant Antibody (Infliximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-402CQ Human Anti-TNF Recombinant Antibody (TAB-402CQ) ELISA Chimeric (mouse/human) IgG
TAB-148CQ-S(P) Anti-Human TNF Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) ELISA Mouse scFv
TAB-148CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)

Rat Antibody

CAT Product Name Application Type
TAB-623CL Bovine Anti-TNF Recombinant Antibody (TAB-623CL) Neut Bovine IgG

Humanized Antibody

CAT Product Name Application Type
TAB-124CQ Human Anti-TNF Recombinant Antibody (TAB-124CQ) FuncS, Neut Humanized antibody
TAB-125CQ Human Anti-TNF Recombinant Antibody (TAB-125CQ) ELISA, Neut Humanized antibody
TAB-126CQ Human Anti-TNF Recombinant Antibody (TAB-126CQ) ELISA, Neut Humanized antibody
TAB-127CQ Human Anti-TNF Recombinant Antibody (TAB-127CQ) ELISA, Neut Humanized antibody
TAB-128CQ Human Anti-TNF Recombinant Antibody (TAB-128CQ) ELISA, FuncS Humanized antibody

Non-hyper Galactosylated

CAT Product Name Application Type
Gly-083LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-085LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-163LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0609MZ Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY Indirect ELISA, WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2057CQ Rat Anti-Tnf Recombinant Antibody (clone XT3) Block, ELISA, IHC, WB Rat IgG1
NEUT-2070CQ Mouse Anti-TNF Recombinant Antibody (clone 4F4) Block, ELISA, ICC, IF, IHC, WB Mouse IgG1
NEUT-2071CQ Rabbit Anti-TNF Recombinant Antibody (clone 6E10) Block, ELISA, IHC, WB Rabbit IgG1
NEUT-2082CQ Mouse Anti-TNF Recombinant Antibody (clone B-C7) Block Mouse IgG1

Recombinant Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-768 Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-006 Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-010 Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced FC, IP, ELISA, Neut, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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