Anti-Human TNF Recombinant Antibody (YHB1411-2) (CAT#: TAB-118CQ)
The humanized antibody exhibits a high antigen binding affinity of picomole level (Kd=1.7 pM) and a low dissociation constant. It can be effectively used for treating a hTNF-α-related diseases such as rheumatoid arthritis.
Specific Inquiry
FC
Figure 1 Binding activity of the antagonists for yeast surface-displayed, (a) native and (b) heat-denatured wildtype TNFα, monitored by flow cytometry.
Kim, M. S., Lee, S. H., Song, M. Y., Yoo, T. H., Lee, B. K., & Kim, Y. S. (2007). Comparative analyses of complex formation and binding sites between human tumor necrosis factor-alpha and its three antagonists elucidate their different neutralizing mechanisms. Journal of molecular biology, 374(5), 1374-1388.
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- YHB1411-2
- Applications
- FC, ELISA
- Related Disease
- Rheumatoid arthritis
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone YHB1411-2"
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-051 | Recombinant Anti-human TNF VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-412CQ | Anti-Human TNF Therapeutic Single Domain Antibody (TAR1-5-19) | ELISA, Inhib | Single domain antibody |
| TAB-413CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL18) | ELISA, WB, Neut | Single domain antibody |
| TAB-414CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL11) | ELISA, WB, Neut | Single domain antibody |
| TAB-415CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL18-3L-VL11) | ELISA, WB, Neut, FunS | Single domain antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-768 | Anti-TNF alpha Recombinant Antibody (Nerelimomab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 |
| TAB-718 | Anti-TNFα Recombinant Antibody (Afelimomab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | F(ab')2 - G3 - kappa |
| TAB-311CT | Anti-Human TNFα/RANKL Recombinant Antibody (8G12) | Neut, ELISA, FC | |
| TAB-311CT-S(P) | Anti-Human TNFα/RANKL Recombinant Antibody scFv Fragment (8G12) | Neut, ELISA, FC | |
| TAB-271CQ-S(P) | Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-271CQ-S(P)) | ELISA, WB | Rabbit scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-006 | Anti-Human TNF Recombinant Antibody (Infliximab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-148CQ | Anti-Human TNF Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-148CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-402CQ-S(P) | Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) | ELISA | Mouse scFv |
| TAB-402CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-034-F(E) | Anti-Human TNF alpha Recombinant Antibody Fab Fragment (Certolizumab Pegol) | ELISA, FC, IP, FuncS, IF, Neut, IHC | Fab' |
| TAB-110CQ | Anti-Human TNF Recombinant Antibody (CDP571) | ELISA | Humanized antibody |
| TAB-114CQ | Human Anti-TNF Recombinant Antibody (TAB-114CQ) | ELISA, FC, Inhib | Humanized antibody |
| TAB-115CQ | Human Anti-TNF Recombinant Antibody (TAB-115CQ) | ELISA, FC, Neut | Humanized antibody |
| TAB-124CQ | Human Anti-TNF Recombinant Antibody (TAB-124CQ) | FuncS, Neut | Humanized antibody |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-623CL | Bovine Anti-TNF Recombinant Antibody (TAB-623CL) | Neut | Bovine IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-142CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-142CQ-F(E)) | ELISA, Neut | Human Fab |
| TAB-143CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-143CQ-F(E)) | ELISA, Neut | Human Fab |
| TAB-144CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-144CQ-F(E)) | ELISA, Neut | Human Fab |
| TAB-404CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (BPC1494) | ELISA, WB | Human antibody |
| TAB-405CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (XENP6401) | ELISA | Human antibody |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-083LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
| Gly-088LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation) | ELISA, FC | Human antibody |
| Gly-098LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation) | ELISA | Human antibody |
| Gly-099LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
| Gly-100LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
Non-hyper Galactosylated
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-083LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
Sialylated IgG Glycan
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-085LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
| Gly-163LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA | Chimeric antibody (mouse/human) |
Hyper-galactosylated
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-086LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
| Gly-087LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0609MZ | Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2051CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL589) | ELISA, ICC, Neut | Mouse IgG1 |
| NEUT-2052CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL570) | WB, Neut | Mouse IgG2b |
| NEUT-2053CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL571) | WB, Neut | Mouse IgG1 |
| NEUT-2054CQ | Rat Anti-Tnf Recombinant Antibody (clone mAb0856) | Neut | Rat IgG1 |
| NEUT-2055CQ | Rat Anti-Tnf Recombinant Antibody (clone V1q(H8)) | Neut, FC | Rat IgD |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2057CQ | Rat Anti-Tnf Recombinant Antibody (clone XT3) | Block, ELISA, IHC, WB | Rat IgG1 |
| NEUT-2070CQ | Mouse Anti-TNF Recombinant Antibody (clone 4F4) | Block, ELISA, ICC, IF, IHC, WB | Mouse IgG1 |
| NEUT-2071CQ | Rabbit Anti-TNF Recombinant Antibody (clone 6E10) | Block, ELISA, IHC, WB | Rabbit IgG1 |
| NEUT-2082CQ | Mouse Anti-TNF Recombinant Antibody (clone B-C7) | Block | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4461 | Rabbit Anti-TNF Recombinant Antibody (clone SI555DS) | Neut | Rabbit IgG |
| MOR-4462 | Rabbit Anti-TNF Recombinant Antibody (clone SI556DS) | FC | Rabbit IgG |
| MOR-4463 | Rabbit Anti-TNF Recombinant Antibody (clone SI557DS) | FC | Rabbit IgG |
| MOR-4464 | Rabbit Anti-TNF Recombinant Antibody (clone SI558DS) | FC | Rabbit IgG |
| MOR-4465 | Rabbit Anti-TNF Recombinant Antibody (clone SI559DS) | FC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-YC | Human Anti-TNF Recombinant Antibody (clone cA2) | ELISA, Neut | Chimeric (mouse/human) IgG1 |
| HPAB-0046-FY | Mouse Anti-TNF Recombinant Antibody (clone 1B7) | Neut | Mouse IgG |
| HPAB-0321CQ | Human Anti-TNF Recombinant Antibody (clone mAb A1) | ELISA, Neut | Human IgG |
| HPAB-0322CQ | Rat Anti-TNF Recombinant Antibody (HPAB-0322CQ) | WB, ELISA, Cyt, FuncS | Rat IgG |
| HPAB-0323CQ | Rat Anti-TNF Recombinant Antibody (HPAB-0323CQ) | ELISA, FuncS | Rat IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0151-YC-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0151-YC-F(E)) | ELISA, Inhib, FuncS | Human Fab |
| HPAB-0675-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0675-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0676-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0676-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0677-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0677-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0678-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0678-CN-F(E)) | ELISA, Neut | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-768 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-006 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-010 | Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1921-FY-F(E) | Human Anti-TNF Recombinant Antibody (clone 9E7); scFv Fragment | Inhib | Human scFv |
| HPAB-1922-FY-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-1922-FY-F(E)) | ELISA | Human Fab |
| HPAB-1923-FY-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-1923-FY-F(E)) | ELISA | Human Fab |
| HPAB-1924-FY-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-1924-FY-F(E)) | ELISA | Human Fab |
| HPAB-1925-FY-F(E) | Mouse Anti-TNF Recombinant Antibody (clone Mab32); scFv Fragment | ELISA | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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