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Anti-Human TNF Recombinant Antibody (YHB1411-2) (CAT#: TAB-118CQ)

The human antibody exhibits a high antigen binding affinity of picomole level and a low dissociation constant. It can be effectively used for treating a hTNF-α-related diseases such as rheumatoid arthritis.

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FC

Figure 1 Binding activity of the antagonists for yeast surface-displayed, (a) native and (b) heat-denatured wildtype TNFα, monitored by flow cytometry.

Figure 1 Binding activity of the antagonists for yeast surface-displayed, (a) native and (b) heat-denatured wildtype TNFα, monitored by flow cytometry.

Kim, M. S., Lee, S. H., Song, M. Y., Yoo, T. H., Lee, B. K., & Kim, Y. S. (2007). Comparative analyses of complex formation and binding sites between human tumor necrosis factor-alpha and its three antagonists elucidate their different neutralizing mechanisms. Journal of molecular biology, 374(5), 1374-1388.


Specifications

  • Host Species
  • Human
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • YHB1411-2
  • Applications
  • FC, ELISA
  • Related Disease
  • Rheumatoid arthritis

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
TAB-768 Anti-TNF alpha Recombinant Antibody (Nerelimomab) FuncS, IF, Neut, ELISA, FC, IP, ICC IgG1
TAB-311CT Anti-Human TNFα/RANKL Recombinant Antibody (8G12) Neut, ELISA, FC
TAB-311CT-S(P) Anti-Human TNFα/RANKL Recombinant Antibody scFv Fragment (8G12) Neut, ELISA, FC
TAB-139CQ-S(P) Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-139CQ-S(P)) ELISA, FC, IF Rabbit scFv
TAB-271CQ-S(P) Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-271CQ-S(P)) ELISA, WB Rabbit scFv

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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