Anti-Human TNF Recombinant Antibody (YHB1411-2) (CAT#: TAB-118CQ)
The human antibody exhibits a high antigen binding affinity of picomole level and a low dissociation constant. It can be effectively used for treating a hTNF-α-related diseases such as rheumatoid arthritis.
Specific Inquiry
FC
Figure 1 Binding activity of the antagonists for yeast surface-displayed, (a) native and (b) heat-denatured wildtype TNFα, monitored by flow cytometry.
Kim, M. S., Lee, S. H., Song, M. Y., Yoo, T. H., Lee, B. K., & Kim, Y. S. (2007). Comparative analyses of complex formation and binding sites between human tumor necrosis factor-alpha and its three antagonists elucidate their different neutralizing mechanisms. Journal of molecular biology, 374(5), 1374-1388.
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- YHB1411-2
- Applications
- FC, ELISA
- Related Disease
- Rheumatoid arthritis
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-010 | Anti-Human TNF Recombinant Antibody (TAB-010) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG1, κ |
| TAB-150CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-150CQ-F(E)) | ELISA, Neut | Human Fab |
| TAB-404CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (BPC1494) | ELISA, WB | Human antibody |
| TAB-405CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (XENP6401) | ELISA | Human antibody |
| TAB-406CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (GB232) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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