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Anti-Human TNFα/RANKL Recombinant Antibody Fab Fragment (8G12) (CAT#: TAB-311CT-F(E))

Recombinant monoclonal antibody specifically binds to RANKL and human TNF-α. This antibody can effectively alleviate the apoptotic effects induced by TNF-a and against ovarian ablation induced osteoporosis model.

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  • Gene Expression
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Normal Tissue
Figure 1 Tonsil
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF

Specifications

  • Immunogen
  • RANKL-TNF fusion protein
  • Host Species
  • Mouse
  • Derivation
  • Mouse hybridoma cell line
  • Specificity
  • Human
  • Species Reactivity
  • Human RANKL, Human THFα
  • Clone
  • 8G12
  • Applications
  • Used for immunoassay techniques such as: Neutralization; Enzyme-linked Immunosorbent Assay; Flow Cytometry
  • Related Disease
  • Osteoporosis model

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor; AVX-470

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
TAB-006 Anti-Human TNF Recombinant Antibody (Infliximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-148CQ Anti-Human TNF Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-402CQ Human Anti-TNF Recombinant Antibody (TAB-402CQ) ELISA Chimeric (mouse/human) IgG
TAB-148CQ-S(P) Anti-Human TNF Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-148CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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