Anti-Human TNF Recombinant Antibody scFv Fragment (mAb2071) (CAT#: TAB-145CQ-S(P))
The antibody scFv Fragment binds to tumor necrosis factor α (TNFα) and blocks the ability of TNFα to bind to its receptor.
Specific Inquiry
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Figure 1 Anti-TNFα human MAbs 2071 and 2060 compared with Remicade®.
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Figure 2 Anti-TNFα human MAbs 2071 and 2090 compared with Remicade® and Humira®.
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Figure 3 TNFα receptor blocking assay.
Results of the TNFα receptor blocking assay comparing control TNFα antibodies Remicade® and Humira® and anti-TNFα human MAbs 2071 and 2090, and control IgG.
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Figure 4 HUVEC assay.
Comparison of inhibition of the TNFα-induced cell surface expression of adhesion molecules with human umbilical vein endothelial cells (HUVEC) using control TNFα antibodies Remicade® and Humira® and anti-TNFα human MAbs 2071, 2090 and 271.
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Figure 5 IL8 assay.
Measurement of TNFα-induced expression of IL-8 by human monocytes using control TNFα antibodies Remicade® and Humira® and anti-TNFα human MAbs 22071 and 2090, and control IgG.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- mAb2071
- Applications
- ELISA, BL, FC, Neut, WB, Inhib, FuncS
- Related Disease
- Rheumatoid arthritis
Applications
- Application Notes
- The antibody was validated for ELISA, Blocking, Inhibition and Function assay. For details, refer to Published Data.
Target
- Alternative Names
- TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody
Mouse Antibody
Rat Antibody
Humanized Antibody
Chimeric Antibody
Single-domain Antibody
Fc Glycosylation
Non-hyper Galactosylated
Sialylated IgG Glycan
Hyper-galactosylated
Chicken IgY Antibody
Blocking Antibody
Neutralizing Antibody
Rabbit Monoclonal Antibody
Recombinant Antibody
Fab Fragment Antibody
ADCC Enhanced Antibody
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-010 | Anti-Human TNF Recombinant Antibody (TAB-010) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG1, κ |
| TAB-111CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (B5) | ELISA, WB | Human antibody |
| TAB-113CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-113CQ-F(E)) | ELISA | Human Fab |
| TAB-404CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (BPC1494) | ELISA, WB | Human antibody |
| TAB-405CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (XENP6401) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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