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    Anti-Human CD40 Recombinant Antibody Fab Fragment (2.220) (CAT#: TAB-187LC-F(E))

    This product is specifically targeting for CD40. It exhibited greater consistency in its ability to elicit mild costimulatory activity. Moreover, the mAb caused a sustained antigen-specific immunosuppression, which was reversible. This is a Fab fragment antibody, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.

    Specific Inquiry
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    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Lymph node
    Figure 1 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg
    Figure 2 Tonsil
    Figure 2 Tonsil
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg
    RNA Expression
    Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
    Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
    Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
    Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40

    Specifications

    • Immunogen
    • hCD40-mG2b
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Clone
    • 2.220
    • Applications
    • SPR, ELISA
    • Related Disease
    • Arthritis, Skin transplantation

    Target

    • Alternative Names
    • CD40; p50; Bp50; CDW40; TNFRSF5

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    TAB-759 Anti-CD40 Recombinant Antibody (Lucatumumab) ELISA, FC, IP, FuncS, IF, Neut, IHC IgG1 - kappa
    TAB-195LC-F(E) Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-195LC-F(E)) ELISA Human Fab
    TAB-196LC-F(E) Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-196LC-F(E)) ELISA Human Fab
    TAB-197LC-F(E) Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-197LC-F(E)) ELISA Human Fab
    TAB-198LC-F(E) Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-198LC-F(E)) ELISA Human Fab

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